| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 chromosome, complete genome. |
|---|---|
| Accession | NC_011883 |
| Length | 2,873,437 |
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The map label for this gene is braF [H]
Identifier: 220903753
GI number: 220903753
Start: 583416
End: 584186
Strand: Direct
Name: braF [H]
Synonym: Ddes_0475
Alternate gene names: 220903753
Gene position: 583416-584186 (Clockwise)
Preceding gene: 220903752
Following gene: 220903754
Centisome position: 20.3
GC content: 58.24
Gene sequence:
>771_bases ATGAGCCTTTTGCGCCTGCAGGAAATGACCAAGGTTTTTGGCGGTCTTGTGGCTGTCAACGATCTCACCTTCAGTGTTGA CGCGGGCAGCGTTGTGGGCCTTATCGGTCCCAACGGGGCGGGCAAGACCACGGTATTCAACTGCATTACCGGCAACTATA CGCCTGAAAAGGGCCGTATCTTCTTTGACGGCGAGCCTATTGCCGGACTCAAGCCCCATCGTGTTGTGGAACTTGGCATT GCTCGCACCTTTCAGAGCATACGGCTTTTCGGCAAACTTTCCGTTCTGGAAAATGTGCTTGCCGGGCGGCACTGCCGCAT GAAGTCGGGCATGATGTCGTGCATGCTGCATCTGCCCTGGCAGCGCAGTGAAGAGCGGGCCGCCGTGGCGCGCTGCATGG AAGAACTGCGTTTTGTAGGCCTGGCCGATAACCATGCCGAAGCCGCCGGGGGACTTTCTTACGGCAACCAGCGGCTGCTT GAAATCGCCCGTGCGCTGGCATCAGACCCACGGCTGCTCATTCTGGACGAGCCTGCCGGTGGTATGAATGATCAGGAAAC AGTGGCTCTTGTAGACACCATCGCGGCCATTCGCGACAGGGGGATTACGGTGCTGCTGATTGAGCATGACATGCGGCTGG TCATGAAAATATGTGAAAAACTGGTGGTGCTGGAGCACGGCACCATGATAGCCCAGGGCGAGCCGGAGGCCGTGCGCCGG AATCCGGCCGTGGTGGAAGCCTACCTGGGCGTAGAAGACGAGAAGTGGTAA
Upstream 100 bases:
>100_bases CGCGCCGCCGCCGTTACCACGTGGATGCCCTTTCCGGAGAAAACGTCCCGCAGGATGCCCCGGGTGAGGGGGATAGCGGG ACTGCCAGCGGGAGGCCCGC
Downstream 100 bases:
>100_bases GCCATGTGCCTGTTGCAACTTTCTGACATACGGGTGAGCTACGGCAGCGTCGAGGTGCTGCACGGCATCAACCTGCGGGT GGAAGAGGGCGAGATAGTCA
Product: ABC transporter-like protein
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 256; Mature: 255
Protein sequence:
>256_residues MSLLRLQEMTKVFGGLVAVNDLTFSVDAGSVVGLIGPNGAGKTTVFNCITGNYTPEKGRIFFDGEPIAGLKPHRVVELGI ARTFQSIRLFGKLSVLENVLAGRHCRMKSGMMSCMLHLPWQRSEERAAVARCMEELRFVGLADNHAEAAGGLSYGNQRLL EIARALASDPRLLILDEPAGGMNDQETVALVDTIAAIRDRGITVLLIEHDMRLVMKICEKLVVLEHGTMIAQGEPEAVRR NPAVVEAYLGVEDEKW
Sequences:
>Translated_256_residues MSLLRLQEMTKVFGGLVAVNDLTFSVDAGSVVGLIGPNGAGKTTVFNCITGNYTPEKGRIFFDGEPIAGLKPHRVVELGI ARTFQSIRLFGKLSVLENVLAGRHCRMKSGMMSCMLHLPWQRSEERAAVARCMEELRFVGLADNHAEAAGGLSYGNQRLL EIARALASDPRLLILDEPAGGMNDQETVALVDTIAAIRDRGITVLLIEHDMRLVMKICEKLVVLEHGTMIAQGEPEAVRR NPAVVEAYLGVEDEKW >Mature_255_residues SLLRLQEMTKVFGGLVAVNDLTFSVDAGSVVGLIGPNGAGKTTVFNCITGNYTPEKGRIFFDGEPIAGLKPHRVVELGIA RTFQSIRLFGKLSVLENVLAGRHCRMKSGMMSCMLHLPWQRSEERAAVARCMEELRFVGLADNHAEAAGGLSYGNQRLLE IARALASDPRLLILDEPAGGMNDQETVALVDTIAAIRDRGITVLLIEHDMRLVMKICEKLVVLEHGTMIAQGEPEAVRRN PAVVEAYLGVEDEKW
Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI45446740, Length=232, Percent_Identity=28.8793103448276, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI47078218, Length=232, Percent_Identity=28.8793103448276, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI105990541, Length=234, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI150417984, Length=241, Percent_Identity=29.045643153527, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI27881501, Length=231, Percent_Identity=28.1385281385281, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI30795238, Length=231, Percent_Identity=28.1385281385281, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI116734710, Length=240, Percent_Identity=28.75, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI31657092, Length=256, Percent_Identity=25.78125, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI9955968, Length=218, Percent_Identity=28.8990825688073, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI9955966, Length=218, Percent_Identity=28.8990825688073, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI45243524, Length=218, Percent_Identity=28.8990825688073, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI73747915, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI21536376, Length=229, Percent_Identity=25.764192139738, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI9665248, Length=235, Percent_Identity=26.8085106382979, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4557481, Length=222, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI171184400, Length=225, Percent_Identity=29.3333333333333, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI153792144, Length=216, Percent_Identity=24.537037037037, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI148612844, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI255708477, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI73747917, Length=164, Percent_Identity=30.4878048780488, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789864, Length=249, Percent_Identity=44.1767068273092, Blast_Score=223, Evalue=9e-60, Organism=Escherichia coli, GI1789593, Length=250, Percent_Identity=32.8, Blast_Score=131, Evalue=3e-32, Organism=Escherichia coli, GI87082268, Length=248, Percent_Identity=30.241935483871, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1790190, Length=255, Percent_Identity=29.0196078431373, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI48995001, Length=228, Percent_Identity=28.5087719298246, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1789991, Length=230, Percent_Identity=33.4782608695652, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1786398, Length=247, Percent_Identity=29.9595141700405, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI1790525, Length=224, Percent_Identity=29.4642857142857, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI87081709, Length=244, Percent_Identity=29.0983606557377, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1788450, Length=255, Percent_Identity=32.156862745098, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1787370, Length=241, Percent_Identity=29.8755186721992, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=26.9709543568465, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1788472, Length=235, Percent_Identity=30.2127659574468, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87081791, Length=246, Percent_Identity=26.4227642276423, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1790739, Length=253, Percent_Identity=29.2490118577075, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1789672, Length=243, Percent_Identity=24.6913580246914, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1788897, Length=223, Percent_Identity=27.8026905829596, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1788210, Length=247, Percent_Identity=25.9109311740891, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1788761, Length=247, Percent_Identity=27.1255060728745, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1787792, Length=263, Percent_Identity=26.615969581749, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1786803, Length=236, Percent_Identity=27.5423728813559, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1788225, Length=249, Percent_Identity=27.3092369477912, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1786345, Length=230, Percent_Identity=28.695652173913, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1790544, Length=254, Percent_Identity=25.9842519685039, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1787712, Length=256, Percent_Identity=26.171875, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI87081782, Length=242, Percent_Identity=26.8595041322314, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787089, Length=236, Percent_Identity=24.5762711864407, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789032, Length=231, Percent_Identity=25.5411255411255, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1786319, Length=229, Percent_Identity=27.0742358078603, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789586, Length=244, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1786253, Length=253, Percent_Identity=28.4584980237154, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789873, Length=230, Percent_Identity=28.695652173913, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI87081834, Length=209, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1786872, Length=241, Percent_Identity=23.2365145228216, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1786563, Length=229, Percent_Identity=30.5676855895196, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI48994943, Length=241, Percent_Identity=31.5352697095436, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789891, Length=217, Percent_Identity=28.110599078341, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1786654, Length=219, Percent_Identity=27.8538812785388, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1788506, Length=223, Percent_Identity=27.8026905829596, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787164, Length=227, Percent_Identity=28.1938325991189, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI87082267, Length=254, Percent_Identity=27.1653543307087, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1787759, Length=254, Percent_Identity=25.9842519685039, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1786698, Length=214, Percent_Identity=26.1682242990654, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787112, Length=216, Percent_Identity=26.3888888888889, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1788644, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787500, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI48994883, Length=255, Percent_Identity=26.2745098039216, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787105, Length=228, Percent_Identity=24.1228070175439, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787143, Length=223, Percent_Identity=26.9058295964126, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI2367384, Length=221, Percent_Identity=28.9592760180996, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI145693107, Length=232, Percent_Identity=28.448275862069, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=25.9615384615385, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1789962, Length=230, Percent_Identity=21.7391304347826, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1787041, Length=240, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1788053, Length=204, Percent_Identity=27.9411764705882, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17565938, Length=223, Percent_Identity=32.7354260089686, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17543740, Length=220, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17510237, Length=239, Percent_Identity=28.0334728033473, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI71992290, Length=223, Percent_Identity=29.5964125560538, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71983523, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI71983516, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI71983510, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17533971, Length=215, Percent_Identity=29.3023255813954, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI115533608, Length=215, Percent_Identity=28.3720930232558, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17565586, Length=221, Percent_Identity=28.9592760180996, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17511077, Length=207, Percent_Identity=29.951690821256, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17541710, Length=212, Percent_Identity=28.7735849056604, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI115533592, Length=224, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115534520, Length=240, Percent_Identity=26.25, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI24643674, Length=237, Percent_Identity=27.4261603375527, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24641565, Length=226, Percent_Identity=28.3185840707965, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI221512771, Length=236, Percent_Identity=25.8474576271186, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI28571209, Length=230, Percent_Identity=24.3478260869565, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI221500365, Length=235, Percent_Identity=23.8297872340426, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007184, Length=235, Percent_Identity=23.8297872340426, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28573571, Length=231, Percent_Identity=25.5411255411255, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI28573573, Length=231, Percent_Identity=25.5411255411255, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007328, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28574150, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24650853, Length=222, Percent_Identity=26.1261261261261, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24650855, Length=222, Percent_Identity=26.1261261261261, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI281362751, Length=222, Percent_Identity=26.5765765765766, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24666092, Length=238, Percent_Identity=24.7899159663866, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24659289, Length=224, Percent_Identity=26.7857142857143, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 27982; Mature: 27851
Theoretical pI: Translated: 6.25; Mature: 6.25
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 6.2 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLLRLQEMTKVFGGLVAVNDLTFSVDAGSVVGLIGPNGAGKTTVFNCITGNYTPEKGRI CCHHHHHHHHHHHCCEEEEECEEEEECCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEE FFDGEPIAGLKPHRVVELGIARTFQSIRLFGKLSVLENVLAGRHCRMKSGMMSCMLHLPW EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC QRSEERAAVARCMEELRFVGLADNHAEAAGGLSYGNQRLLEIARALASDPRLLILDEPAG CCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCC GMNDQETVALVDTIAAIRDRGITVLLIEHDMRLVMKICEKLVVLEHGTMIAQGEPEAVRR CCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHC NPAVVEAYLGVEDEKW CCCEEEEEECCCCCCC >Mature Secondary Structure SLLRLQEMTKVFGGLVAVNDLTFSVDAGSVVGLIGPNGAGKTTVFNCITGNYTPEKGRI CHHHHHHHHHHHCCEEEEECEEEEECCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEE FFDGEPIAGLKPHRVVELGIARTFQSIRLFGKLSVLENVLAGRHCRMKSGMMSCMLHLPW EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC QRSEERAAVARCMEELRFVGLADNHAEAAGGLSYGNQRLLEIARALASDPRLLILDEPAG CCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCC GMNDQETVALVDTIAAIRDRGITVLLIEHDMRLVMKICEKLVVLEHGTMIAQGEPEAVRR CCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHC NPAVVEAYLGVEDEKW CCCEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2120183; 10984043 [H]