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The map label for this gene is accA [H]

Identifier: 220903736

GI number: 220903736

Start: 552700

End: 554958

Strand: Reverse

Name: accA [H]

Synonym: Ddes_0458

Alternate gene names: 220903736

Gene position: 554958-552700 (Counterclockwise)

Preceding gene: 220903737

Following gene: 220903735

Centisome position: 19.31

GC content: 60.29

Gene sequence:

>2259_bases
ATGCGAGTTATGGACAATAATATAGAGAAACGAATCCAGAGTCTGCGCGACAGGCTCAGTTATATGGTGGACATTTTTGC
CGGCAAGCACAAAGACAATGCGCAACTGCTGGAAGAAAAGCTCACCTCTTTCGCGGCACGCGCCCGTGCGGGGGAAATTG
AAGACCCCTATGCGGAGCTGGCCACGGTTGAAGACCTGTTCTGCTATGTGGAGCGCCGCCTTGAAGGCAACATTACTCCC
ATGGACAAGGTGCGCATCGTGCGCCACCCGCAGCGCATCTGTCTGCGGGACATCCTGGAAAACGTCTACGACAACTTCAC
CGAAGTCGGGGGACAGGACGAGCACAGCCTGGACCCCAGCATGCTCATAGCCCGCGCCGTCATTACCCGGCGCAGGGGCA
AGAAGACCTATACCCAGTCCGTCATGGTTATCGGGCAGGAAAAAGGCCACGGGGCGGAGTTCCGCAACGGCGGCTCGGTC
AAGCCCTGGGGCAACGCCAAGGCGCAGCAGTATATGCGCGTTGCGGAAACCGAGGGCATTCCCGTACATGCCTATATCTT
CACGCCCGGCTCGTATCCCATTGAGGACTACCCCGGCGCGGCCCAGCAGATCGCGCGCAATATCTACAGCATGGCCGGTC
TGCGCGTACCCGTTATCGCCGTCATTTCCGAAGGCGGTTCCGGCGGGGCCGAGGCCATAGGCCTGGCGGATAAAAGGCTG
ATGCTTTCGCATGGCTACTATTCGGTCATTTCACCCGAAGGGGCCGCAGCCATTGAAGGCCGCCTCAAGTCCGGGCAGCG
TGCTGCCCCCGAACTGATCGAGCACTGCGCCCAGAACCTCAAGATCACCGCGCAGGACAACATCAAGTTCGGCTATATCG
ATCGCATCGTGCAGGAGCCGCCACTGGGCGCGCGCCCCTGGCACTTCGACTTTTTCCGCACCTTGCGGCAAGAAGTCATA
CGCGCCACAGACGAAGTGGTGGTTTCCACCCGCGTGATGCCCATCCTCAAGGGCTTCACGCTTTCACGCCTACGCAGGCC
CGATGCCAACCTGGATGAAATGCATACCCGCTGGGGGCTTTCTTCCAAGGCCAAAGACCGCCTGCGCGAACGCCGCCAGC
AGAAGTTTCTGCGGCTTTCCCGTCAGGCGGCGCGTGACCGCAGGCCCTTCATCACCAAGATGGCGGGCGCAGCCTGGGAC
TGGATATCCAAGCCCTGGGTCAGCTTCAAATACGACTTCTATCGCAAGCATCAACGCCGCATCCGTACCTTTATGGAAGA
AATGGGCAACGAGTGGGATGTGTTCAAGGGCCGCCTGCTGGCTCCCTGGCACAAGCTTACCCATAAACTGCCCGGCAAGC
AGGACAACAAGGCCAGGGAACTCATGGCCCTTTCCACCTGGGCAGACGATTCGCGCCGCCTCAAGTGGAACTACATATCC
CCGCGCTACAAGGCCGACCGTACGGTTACCTGCCCCAACAGCGCCTCTTACGGCTGCCTGGACCTCTGGGGACCGGACCT
TTTCGCCGAATTCGCGGGCGTGTGCAGCCATTGCGGCTACCACTTCCCCATGGAGCCGGAATGGTATGTAAAAAACGTCT
TTGACGCCGGTTCGGTCTTTGAGTTCAACAGCGAAATCGAAGCGGGCAATCCGCTGGACTTCCCCGACTTCAACGACCGC
GTCGCCGCTGCCCAGAAAAAAACCGGGGCCAAAAGCGGCTGCATGACCTTCGAGGCCCGTATCGACAATACCAAGATGGT
GGTAGCCATGCTTATGGGTACCTTCCGCGGCGGCTCCGTGGGCGCGGCCGAAGGCTACAAGTTTGTGGAAGCCGCCCAGC
GCGCCGAGAAAAAACGCTATCCCTTCCTGGCATACGTACACGGCACGGCGGGCATACGCATTCAGGAAGGCACACACGGT
GTCATCCAGATGCCGCGCTGCACAGTGGCTGTGCGCCGCTATATCGAATCCGGCGGCCTGTACATGGTGCTGTACGACAC
CAACTCCTTTGCCGGGCCGGTCGCCAGCTTTCTTGGCTGCTCGCCCTACCAGTTCGCCGTGCGTTCATCCAACATCGGCT
TTGCCGGGCCGGGCGTTATCAAGGAAACCACGGGGATGGACATCCCGCCCAAGTACCACCGCTCGTACCGCGCCCTGTCA
CGCGGGCACATCCAGGGCATATGGGACAGAAGGCAGGTGCGCGCGAACCTCAAGCAGGCGCTGCTCACCATCGGCGGCAG
AAACCTTTATTACCGGTAG

Upstream 100 bases:

>100_bases
GACCGTTCTGGCCGTCAAGGACCGCATGCTCGGCAACAATCCGCTGGCCGCCCTGCACTCATCCTACTCCAATTACCTCA
AAAAACCCGTTTAGCGGCGC

Downstream 100 bases:

>100_bases
GCAAAAAAGCATGCCGGGGACGGATGACAAGGCGTTGCCGCCAGATCAGCGCTTTCGTTCCCGGCCGTAAAAACTGCGCT
GCAGGCAGGGGATGCACCCC

Product: acetyl-CoA carboxylase

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 752; Mature: 752

Protein sequence:

>752_residues
MRVMDNNIEKRIQSLRDRLSYMVDIFAGKHKDNAQLLEEKLTSFAARARAGEIEDPYAELATVEDLFCYVERRLEGNITP
MDKVRIVRHPQRICLRDILENVYDNFTEVGGQDEHSLDPSMLIARAVITRRRGKKTYTQSVMVIGQEKGHGAEFRNGGSV
KPWGNAKAQQYMRVAETEGIPVHAYIFTPGSYPIEDYPGAAQQIARNIYSMAGLRVPVIAVISEGGSGGAEAIGLADKRL
MLSHGYYSVISPEGAAAIEGRLKSGQRAAPELIEHCAQNLKITAQDNIKFGYIDRIVQEPPLGARPWHFDFFRTLRQEVI
RATDEVVVSTRVMPILKGFTLSRLRRPDANLDEMHTRWGLSSKAKDRLRERRQQKFLRLSRQAARDRRPFITKMAGAAWD
WISKPWVSFKYDFYRKHQRRIRTFMEEMGNEWDVFKGRLLAPWHKLTHKLPGKQDNKARELMALSTWADDSRRLKWNYIS
PRYKADRTVTCPNSASYGCLDLWGPDLFAEFAGVCSHCGYHFPMEPEWYVKNVFDAGSVFEFNSEIEAGNPLDFPDFNDR
VAAAQKKTGAKSGCMTFEARIDNTKMVVAMLMGTFRGGSVGAAEGYKFVEAAQRAEKKRYPFLAYVHGTAGIRIQEGTHG
VIQMPRCTVAVRRYIESGGLYMVLYDTNSFAGPVASFLGCSPYQFAVRSSNIGFAGPGVIKETTGMDIPPKYHRSYRALS
RGHIQGIWDRRQVRANLKQALLTIGGRNLYYR

Sequences:

>Translated_752_residues
MRVMDNNIEKRIQSLRDRLSYMVDIFAGKHKDNAQLLEEKLTSFAARARAGEIEDPYAELATVEDLFCYVERRLEGNITP
MDKVRIVRHPQRICLRDILENVYDNFTEVGGQDEHSLDPSMLIARAVITRRRGKKTYTQSVMVIGQEKGHGAEFRNGGSV
KPWGNAKAQQYMRVAETEGIPVHAYIFTPGSYPIEDYPGAAQQIARNIYSMAGLRVPVIAVISEGGSGGAEAIGLADKRL
MLSHGYYSVISPEGAAAIEGRLKSGQRAAPELIEHCAQNLKITAQDNIKFGYIDRIVQEPPLGARPWHFDFFRTLRQEVI
RATDEVVVSTRVMPILKGFTLSRLRRPDANLDEMHTRWGLSSKAKDRLRERRQQKFLRLSRQAARDRRPFITKMAGAAWD
WISKPWVSFKYDFYRKHQRRIRTFMEEMGNEWDVFKGRLLAPWHKLTHKLPGKQDNKARELMALSTWADDSRRLKWNYIS
PRYKADRTVTCPNSASYGCLDLWGPDLFAEFAGVCSHCGYHFPMEPEWYVKNVFDAGSVFEFNSEIEAGNPLDFPDFNDR
VAAAQKKTGAKSGCMTFEARIDNTKMVVAMLMGTFRGGSVGAAEGYKFVEAAQRAEKKRYPFLAYVHGTAGIRIQEGTHG
VIQMPRCTVAVRRYIESGGLYMVLYDTNSFAGPVASFLGCSPYQFAVRSSNIGFAGPGVIKETTGMDIPPKYHRSYRALS
RGHIQGIWDRRQVRANLKQALLTIGGRNLYYR
>Mature_752_residues
MRVMDNNIEKRIQSLRDRLSYMVDIFAGKHKDNAQLLEEKLTSFAARARAGEIEDPYAELATVEDLFCYVERRLEGNITP
MDKVRIVRHPQRICLRDILENVYDNFTEVGGQDEHSLDPSMLIARAVITRRRGKKTYTQSVMVIGQEKGHGAEFRNGGSV
KPWGNAKAQQYMRVAETEGIPVHAYIFTPGSYPIEDYPGAAQQIARNIYSMAGLRVPVIAVISEGGSGGAEAIGLADKRL
MLSHGYYSVISPEGAAAIEGRLKSGQRAAPELIEHCAQNLKITAQDNIKFGYIDRIVQEPPLGARPWHFDFFRTLRQEVI
RATDEVVVSTRVMPILKGFTLSRLRRPDANLDEMHTRWGLSSKAKDRLRERRQQKFLRLSRQAARDRRPFITKMAGAAWD
WISKPWVSFKYDFYRKHQRRIRTFMEEMGNEWDVFKGRLLAPWHKLTHKLPGKQDNKARELMALSTWADDSRRLKWNYIS
PRYKADRTVTCPNSASYGCLDLWGPDLFAEFAGVCSHCGYHFPMEPEWYVKNVFDAGSVFEFNSEIEAGNPLDFPDFNDR
VAAAQKKTGAKSGCMTFEARIDNTKMVVAMLMGTFRGGSVGAAEGYKFVEAAQRAEKKRYPFLAYVHGTAGIRIQEGTHG
VIQMPRCTVAVRRYIESGGLYMVLYDTNSFAGPVASFLGCSPYQFAVRSSNIGFAGPGVIKETTGMDIPPKYHRSYRALS
RGHIQGIWDRRQVRANLKQALLTIGGRNLYYR

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=231, Percent_Identity=31.1688311688312, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1786382, Length=276, Percent_Identity=34.7826086956522, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 85285; Mature: 85285

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVMDNNIEKRIQSLRDRLSYMVDIFAGKHKDNAQLLEEKLTSFAARARAGEIEDPYAEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ATVEDLFCYVERRLEGNITPMDKVRIVRHPQRICLRDILENVYDNFTEVGGQDEHSLDPS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
MLIARAVITRRRGKKTYTQSVMVIGQEKGHGAEFRNGGSVKPWGNAKAQQYMRVAETEGI
HHHHHHHHHHHCCCHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
PVHAYIFTPGSYPIEDYPGAAQQIARNIYSMAGLRVPVIAVISEGGSGGAEAIGLADKRL
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHCCCHHHH
MLSHGYYSVISPEGAAAIEGRLKSGQRAAPELIEHCAQNLKITAQDNIKFGYIDRIVQEP
HHCCCCEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCEEHHHHHHHCCC
PLGARPWHFDFFRTLRQEVIRATDEVVVSTRVMPILKGFTLSRLRRPDANLDEMHTRWGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SSKAKDRLRERRQQKFLRLSRQAARDRRPFITKMAGAAWDWISKPWVSFKYDFYRKHQRR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCHHEEHHHHHHHHHH
IRTFMEEMGNEWDVFKGRLLAPWHKLTHKLPGKQDNKARELMALSTWADDSRRLKWNYIS
HHHHHHHHCCCCCHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECC
PRYKADRTVTCPNSASYGCLDLWGPDLFAEFAGVCSHCGYHFPMEPEWYVKNVFDAGSVF
CCCCCCCEEECCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEE
EFNSEIEAGNPLDFPDFNDRVAAAQKKTGAKSGCMTFEARIDNTKMVVAMLMGTFRGGSV
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCC
GAAEGYKFVEAAQRAEKKRYPFLAYVHGTAGIRIQEGTHGVIQMPRCTVAVRRYIESGGL
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCEEECCHHHHHHHHHHHCCCE
YMVLYDTNSFAGPVASFLGCSPYQFAVRSSNIGFAGPGVIKETTGMDIPPKYHRSYRALS
EEEEECCCCCCHHHHHHHCCCCHHEEEECCCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
RGHIQGIWDRRQVRANLKQALLTIGGRNLYYR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRVMDNNIEKRIQSLRDRLSYMVDIFAGKHKDNAQLLEEKLTSFAARARAGEIEDPYAEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ATVEDLFCYVERRLEGNITPMDKVRIVRHPQRICLRDILENVYDNFTEVGGQDEHSLDPS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
MLIARAVITRRRGKKTYTQSVMVIGQEKGHGAEFRNGGSVKPWGNAKAQQYMRVAETEGI
HHHHHHHHHHHCCCHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
PVHAYIFTPGSYPIEDYPGAAQQIARNIYSMAGLRVPVIAVISEGGSGGAEAIGLADKRL
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHCCCHHHH
MLSHGYYSVISPEGAAAIEGRLKSGQRAAPELIEHCAQNLKITAQDNIKFGYIDRIVQEP
HHCCCCEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCEEHHHHHHHCCC
PLGARPWHFDFFRTLRQEVIRATDEVVVSTRVMPILKGFTLSRLRRPDANLDEMHTRWGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SSKAKDRLRERRQQKFLRLSRQAARDRRPFITKMAGAAWDWISKPWVSFKYDFYRKHQRR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCHHEEHHHHHHHHHH
IRTFMEEMGNEWDVFKGRLLAPWHKLTHKLPGKQDNKARELMALSTWADDSRRLKWNYIS
HHHHHHHHCCCCCHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECC
PRYKADRTVTCPNSASYGCLDLWGPDLFAEFAGVCSHCGYHFPMEPEWYVKNVFDAGSVF
CCCCCCCEEECCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEE
EFNSEIEAGNPLDFPDFNDRVAAAQKKTGAKSGCMTFEARIDNTKMVVAMLMGTFRGGSV
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCC
GAAEGYKFVEAAQRAEKKRYPFLAYVHGTAGIRIQEGTHGVIQMPRCTVAVRRYIESGGL
CHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCEEECCHHHHHHHHHHHCCCE
YMVLYDTNSFAGPVASFLGCSPYQFAVRSSNIGFAGPGVIKETTGMDIPPKYHRSYRALS
EEEEECCCCCCHHHHHHHCCCCHHEEEECCCCCCCCCCCEECCCCCCCCHHHHHHHHHHH
RGHIQGIWDRRQVRANLKQALLTIGGRNLYYR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA