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The map label for this gene is iorA [H]

Identifier: 220903721

GI number: 220903721

Start: 535226

End: 537082

Strand: Direct

Name: iorA [H]

Synonym: Ddes_0443

Alternate gene names: 220903721

Gene position: 535226-537082 (Clockwise)

Preceding gene: 220903720

Following gene: 220903722

Centisome position: 18.63

GC content: 60.42

Gene sequence:

>1857_bases
ATGAGCAACAATCCCCTGTTGCACGGCGCCCAAGGTGAGCGCCATCTGTTGTTGGGCAACGAGGCCATTGTGCGTGGCGC
TCTTGAGGCCGGTGTGCATGTGGTTACCTGTTATCCGGGTACGCCTTCGTCCGAAGTGCCGGACACTTTCCATCGCATCG
GCGGTGAGGGCCGTTACCGGCTGGAATATTCCGTCAACGAGAAGGTTGCCATGGAGGTGGCCGCAGGCGCTGCCCTTGGC
GGGGCCATGAGCCTTGTGACCGTGAAGCATGTGGGGCTTAACGTGGCCGCCGACCCGTTGTTTACGGCGGTGTATACGGG
CCTGCCCGGTGGCCTGGTTGTACTTTCTGCTGATGACCCCGGCTGCCACTCCAGCCAGAACGAGCAGGACAACCGCTATT
ACGCGCGTTTTGCCATGCTGCCCTGTTTTGAACCGGCCTCGGCGCAGGAAGCCAAGGACATGACGCGCGAGGCCTTCAGC
CTGGCGCGTCGCCTTGAACAGCCCGTGCTGCTGCGCACCACAACGCGGATCAGTCATTTGCGTGGTCCTGTGGATTTTGA
TGCCTTGCCCGCGCCGCAGCCCAAAAAGGATTTCCAGCGTGACCCAGCCCGTTTTGTTCCTGTGCCTGCCGTGGCCCGCA
AGCGGCATGTGGTGCTGGACGAGCTGATGGCCCGTGCCCGTCAGGCCGCGGAAGAAAGTTCCTTCAATACGATTGCCGAA
CCTGCCGAAATCACAAAACTGGGCATCATCACTAGCGGTGTTTCGCGCAACTATCTGGCTGATGCGCTGGCCGCCAATGG
ATGGGAGGGTCGCGTACGTGTGCTGGAACTGGGTATGACCTGGCCCCTGCCCGAAGAAAAAATCTGCACTTTCCTTGCCG
GATGCGAGCGGGTGCTGGTGCTGGAAGAGGGGGAGGACCTGCTGGAACAGGACATTCGTGTTCTGGTGCAGCGGCGTGGT
CTTTCCGTGAGCATTGAAGGCAAAGACGACATTCTCACCCATCAGGGCGAGTATTCCACCACACTTGTCACGCGCCGTCT
GGCCCGTTGGTTTGATGAAACCTGTCCCGTGCGGGAGCCGCGCAGCATGGAGCCAGATCTGCCGGGCCGTCCGCCCAACC
TGTGCCCCGGCTGTTCGCACCGCGCCGTGTATTATACGGTACGGCAGATCTTTGGGGACGAGGCCTATTATTCCAGCGAT
ATCGGCTGCTACACTCTGGGGCTTCTGCCCCCCCTGCGCACGGCTGACTTTCTGGTGTGCATGGGTTCATCCATCTCGGC
AGGCAGCGGTTTTGCCCGGGCCTCGGAAAAACCCGTCATTGCCTTTATCGGCGACTCCACTTTTTTCCATTCCGGTATGA
CCGGGCTTGCCAACGCTGTTTTCAACCAGCATGACGTACTTATGGTCATTCTGGACAACGGCACCACGGCCATGACCGGG
CATCAGCCCAATCCCGGCATGCAGCAGGATGTGCTCGGCAGCATGAGCAGCCATATGGATATTGAAACCATTGTGCGCGG
CATGGGCGTGACCGAAGTGGCCAAGGTGCGTGCCTTCAATATCAAGGCACTTACAGCGGCCCTGAATGACATGAAAGACA
AGCCAGGCGTGCGAGTGCTTATCACCGAAGAGCCATGTGTGCTTTATGCCCGCCGCCAGCTCAAGAAGGTTGCCCCCCAG
GTGGCCGTAGTGGCGCAACAGGGGGCGGAAGCCATGCGCTGCCTTGAAGAGCTTGCCTGCCCTGCGTTTTATCGCCACGG
CGACAATCTGGAGGTGGATGCGACCCTCTGCACGGGCTGCATGGTGTGTTTGCAGGTGGCCCCCGGGGCTTTCAAGGCGC
GCAAGCGCCAGGGATAG

Upstream 100 bases:

>100_bases
TCCGCACTGCGGGTTGTTGTGCAATAAAAGGGTGCGCCACCGGGCGCACCTTGCATTATCAGTGCGGCCCGCGAGCCATG
CGCCGGGGCCGGGAGGAAGC

Downstream 100 bases:

>100_bases
GTGAAAGACAATGACTATGCAGAACAAGCAGAAGCGCATGCGCGTTTACTTTACCGGCGTGGGCGGCCAGGGAACCCTTA
CGGCCACGACCTTGCTGGCC

Product: indolepyruvate ferredoxin oxidoreductase subunit alpha

Products: NA

Alternate protein names: IOR; Indolepyruvate ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 618; Mature: 617

Protein sequence:

>618_residues
MSNNPLLHGAQGERHLLLGNEAIVRGALEAGVHVVTCYPGTPSSEVPDTFHRIGGEGRYRLEYSVNEKVAMEVAAGAALG
GAMSLVTVKHVGLNVAADPLFTAVYTGLPGGLVVLSADDPGCHSSQNEQDNRYYARFAMLPCFEPASAQEAKDMTREAFS
LARRLEQPVLLRTTTRISHLRGPVDFDALPAPQPKKDFQRDPARFVPVPAVARKRHVVLDELMARARQAAEESSFNTIAE
PAEITKLGIITSGVSRNYLADALAANGWEGRVRVLELGMTWPLPEEKICTFLAGCERVLVLEEGEDLLEQDIRVLVQRRG
LSVSIEGKDDILTHQGEYSTTLVTRRLARWFDETCPVREPRSMEPDLPGRPPNLCPGCSHRAVYYTVRQIFGDEAYYSSD
IGCYTLGLLPPLRTADFLVCMGSSISAGSGFARASEKPVIAFIGDSTFFHSGMTGLANAVFNQHDVLMVILDNGTTAMTG
HQPNPGMQQDVLGSMSSHMDIETIVRGMGVTEVAKVRAFNIKALTAALNDMKDKPGVRVLITEEPCVLYARRQLKKVAPQ
VAVVAQQGAEAMRCLEELACPAFYRHGDNLEVDATLCTGCMVCLQVAPGAFKARKRQG

Sequences:

>Translated_618_residues
MSNNPLLHGAQGERHLLLGNEAIVRGALEAGVHVVTCYPGTPSSEVPDTFHRIGGEGRYRLEYSVNEKVAMEVAAGAALG
GAMSLVTVKHVGLNVAADPLFTAVYTGLPGGLVVLSADDPGCHSSQNEQDNRYYARFAMLPCFEPASAQEAKDMTREAFS
LARRLEQPVLLRTTTRISHLRGPVDFDALPAPQPKKDFQRDPARFVPVPAVARKRHVVLDELMARARQAAEESSFNTIAE
PAEITKLGIITSGVSRNYLADALAANGWEGRVRVLELGMTWPLPEEKICTFLAGCERVLVLEEGEDLLEQDIRVLVQRRG
LSVSIEGKDDILTHQGEYSTTLVTRRLARWFDETCPVREPRSMEPDLPGRPPNLCPGCSHRAVYYTVRQIFGDEAYYSSD
IGCYTLGLLPPLRTADFLVCMGSSISAGSGFARASEKPVIAFIGDSTFFHSGMTGLANAVFNQHDVLMVILDNGTTAMTG
HQPNPGMQQDVLGSMSSHMDIETIVRGMGVTEVAKVRAFNIKALTAALNDMKDKPGVRVLITEEPCVLYARRQLKKVAPQ
VAVVAQQGAEAMRCLEELACPAFYRHGDNLEVDATLCTGCMVCLQVAPGAFKARKRQG
>Mature_617_residues
SNNPLLHGAQGERHLLLGNEAIVRGALEAGVHVVTCYPGTPSSEVPDTFHRIGGEGRYRLEYSVNEKVAMEVAAGAALGG
AMSLVTVKHVGLNVAADPLFTAVYTGLPGGLVVLSADDPGCHSSQNEQDNRYYARFAMLPCFEPASAQEAKDMTREAFSL
ARRLEQPVLLRTTTRISHLRGPVDFDALPAPQPKKDFQRDPARFVPVPAVARKRHVVLDELMARARQAAEESSFNTIAEP
AEITKLGIITSGVSRNYLADALAANGWEGRVRVLELGMTWPLPEEKICTFLAGCERVLVLEEGEDLLEQDIRVLVQRRGL
SVSIEGKDDILTHQGEYSTTLVTRRLARWFDETCPVREPRSMEPDLPGRPPNLCPGCSHRAVYYTVRQIFGDEAYYSSDI
GCYTLGLLPPLRTADFLVCMGSSISAGSGFARASEKPVIAFIGDSTFFHSGMTGLANAVFNQHDVLMVILDNGTTAMTGH
QPNPGMQQDVLGSMSSHMDIETIVRGMGVTEVAKVRAFNIKALTAALNDMKDKPGVRVLITEEPCVLYARRQLKKVAPQV
AVVAQQGAEAMRCLEELACPAFYRHGDNLEVDATLCTGCMVCLQVAPGAFKARKRQG

Specific function: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates [H]

COG id: COG4231

COG function: function code C; Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017721
- InterPro:   IPR002880
- InterPro:   IPR011766
- InterPro:   IPR009014 [H]

Pfam domain/function: PF01855 POR_N; PF02775 TPP_enzyme_C [H]

EC number: =1.2.7.8 [H]

Molecular weight: Translated: 67266; Mature: 67135

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNPLLHGAQGERHLLLGNEAIVRGALEAGVHVVTCYPGTPSSEVPDTFHRIGGEGRYR
CCCCCCEECCCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCEEE
LEYSVNEKVAMEVAAGAALGGAMSLVTVKHVGLNVAADPLFTAVYTGLPGGLVVLSADDP
EEEECCCHHHHHHHHHHHHCCHHHHEEHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCC
GCHSSQNEQDNRYYARFAMLPCFEPASAQEAKDMTREAFSLARRLEQPVLLRTTTRISHL
CCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
RGPVDFDALPAPQPKKDFQRDPARFVPVPAVARKRHVVLDELMARARQAAEESSFNTIAE
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAEITKLGIITSGVSRNYLADALAANGWEGRVRVLELGMTWPLPEEKICTFLAGCERVLV
CHHHHEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEE
LEEGEDLLEQDIRVLVQRRGLSVSIEGKDDILTHQGEYSTTLVTRRLARWFDETCPVREP
EECCHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCC
RSMEPDLPGRPPNLCPGCSHRAVYYTVRQIFGDEAYYSSDIGCYTLGLLPPLRTADFLVC
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCEEEE
MGSSISAGSGFARASEKPVIAFIGDSTFFHSGMTGLANAVFNQHDVLMVILDNGTTAMTG
ECCCCCCCCCCCCCCCCCEEEEECCCHHHHCCHHHHHHHHCCCCCEEEEEECCCCEEECC
HQPNPGMQQDVLGSMSSHMDIETIVRGMGVTEVAKVRAFNIKALTAALNDMKDKPGVRVL
CCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
ITEEPCVLYARRQLKKVAPQVAVVAQQGAEAMRCLEELACPAFYRHGDNLEVDATLCTGC
EECCCHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHH
MVCLQVAPGAFKARKRQG
HHHHHHCCCHHHHHCCCC
>Mature Secondary Structure 
SNNPLLHGAQGERHLLLGNEAIVRGALEAGVHVVTCYPGTPSSEVPDTFHRIGGEGRYR
CCCCCEECCCCCEEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCEEE
LEYSVNEKVAMEVAAGAALGGAMSLVTVKHVGLNVAADPLFTAVYTGLPGGLVVLSADDP
EEEECCCHHHHHHHHHHHHCCHHHHEEHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCC
GCHSSQNEQDNRYYARFAMLPCFEPASAQEAKDMTREAFSLARRLEQPVLLRTTTRISHL
CCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
RGPVDFDALPAPQPKKDFQRDPARFVPVPAVARKRHVVLDELMARARQAAEESSFNTIAE
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAEITKLGIITSGVSRNYLADALAANGWEGRVRVLELGMTWPLPEEKICTFLAGCERVLV
CHHHHEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEE
LEEGEDLLEQDIRVLVQRRGLSVSIEGKDDILTHQGEYSTTLVTRRLARWFDETCPVREP
EECCHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCC
RSMEPDLPGRPPNLCPGCSHRAVYYTVRQIFGDEAYYSSDIGCYTLGLLPPLRTADFLVC
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCEEEEECCCCCCCCCEEEE
MGSSISAGSGFARASEKPVIAFIGDSTFFHSGMTGLANAVFNQHDVLMVILDNGTTAMTG
ECCCCCCCCCCCCCCCCCEEEEECCCHHHHCCHHHHHHHHCCCCCEEEEEECCCCEEECC
HQPNPGMQQDVLGSMSSHMDIETIVRGMGVTEVAKVRAFNIKALTAALNDMKDKPGVRVL
CCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
ITEEPCVLYARRQLKKVAPQVAVVAQQGAEAMRCLEELACPAFYRHGDNLEVDATLCTGC
EECCCHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCCEEHHHHHHHH
MVCLQVAPGAFKARKRQG
HHHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]