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The map label for this gene is arnB [H]

Identifier: 220903683

GI number: 220903683

Start: 491975

End: 493225

Strand: Reverse

Name: arnB [H]

Synonym: Ddes_0405

Alternate gene names: 220903683

Gene position: 493225-491975 (Counterclockwise)

Preceding gene: 220903684

Following gene: 220903682

Centisome position: 17.16

GC content: 55.96

Gene sequence:

>1251_bases
ATGGACGATGCCCGGCTTGCCGTTTTGCAAAAACGCGTTGCCGCAGGCGAGGAAGAAGGTTGCGGCAGCGCCTATGCGCA
GGCCTTTTGCGCAGCGCTCGGCGGCGGGTACGCATTGCCAACGGCCTCTGCGCGAATGGCGCTGCATGCGCTGCTGCGGC
ATTATGGTCTTCGTGACGGCGATGAGGTCTTAGTCACAGGCTTTACCTGTTCCGTGGTGCTCAACGCCATACTGCGCTGC
GGCGCGGCACCCCGTTTTGTGGATATAGACAGGCATACCTTGGGCACAAGCCCGGAATCAGTGGAAGCTGCCATTACCCC
ACGAACTAAGGCGCTTATTGCTCAGCATACCTTTGGCGTTCCCTGCGCCATTGATTCGTTGCGCGCTTTGGCAACCCACT
ATCATATCAAACTTATTGAGGATGTGGCGATTGCGTTTGGAAGCAAATACCAGGGCAAGCCGCTTGGCGCATGGGGCGAT
GCCGCCTATTTTTCCACAGACCACTCCAAACCCTTAAATTCCCTTATTGGCGGAATGCTCTACACTACAGACGAAAATCT
GTACGAAAGAATTTTTTCAGAGTATCAGGGCTGGCCGCACCTGCCGCGCGAAAAACAGCAGGCACTGTTGGAACAGGTGC
GTGTGGAGCGCGATAATTTCACTCCGGCCCGCTACCGTTGGCACAACTTTGCCGCGTTGTTTGCCGGGTGCGATGCCCCT
TCCCCTTTCCTTGATGCGGACTACACCCCCTGGGCTGTGCAGGGCGACTACCCCTATCCGGCAAAGATGCCGACAGTTCT
GACAACCCTTGGGCTTGAGGCCCTGCGGCAGTGGCCTGTTGTTGCGGATGAACGGTGCCATTGGTTCAAAAAAATTTCCG
AAGTGTTTTACAGAAATAATTGCGGGGGTATGATTCCTGCGGGCTTTCAGAACATTGGCAAAGAGGTTGTGCCGCTTCGC
TTTGCTTTCTGCCTGCCTGCCGTCTGCGGGCCGCTACGTGAAAACAAAGGCTTGTGGCGGGCCGTCAACGCGTTTTTTCC
GGCAAACTGGATATGGTTTCAGGATCCTGTGGTTTGCCGGGCTACAGATATAACCGCCTATGGCTATACGCCGGGAACCT
GCCCCGTGGCCGAGGAGGTTGGCCGCGGCATTGTGACGATTCCACTGGATGTGCCCTCCCCTTATGCAGACAGATTTATG
CAAAATGTGGAGAATCTTTGTCGTGAGCTTCAGCGGCTGCCTCGGGCTTAA

Upstream 100 bases:

>100_bases
GTGGCGCGCCAGGATGCATCAGGTGACGTTCTGGGTGAAGACGTATGGTCTTCCGTGGTCGCGTGCTCCTTTTTTCCCGT
TTATCAGGCCGCATCATGAC

Downstream 100 bases:

>100_bases
TCAGCCCGACTGAAAACTTGTGCCGGGTGGTCATGCAAAGCATGGGAAAAGATTATACCGCACTTCATGATTATGGCTTG
ATCGGGGCAGCATAACAAGG

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDDARLAVLQKRVAAGEEEGCGSAYAQAFCAALGGGYALPTASARMALHALLRHYGLRDGDEVLVTGFTCSVVLNAILRC
GAAPRFVDIDRHTLGTSPESVEAAITPRTKALIAQHTFGVPCAIDSLRALATHYHIKLIEDVAIAFGSKYQGKPLGAWGD
AAYFSTDHSKPLNSLIGGMLYTTDENLYERIFSEYQGWPHLPREKQQALLEQVRVERDNFTPARYRWHNFAALFAGCDAP
SPFLDADYTPWAVQGDYPYPAKMPTVLTTLGLEALRQWPVVADERCHWFKKISEVFYRNNCGGMIPAGFQNIGKEVVPLR
FAFCLPAVCGPLRENKGLWRAVNAFFPANWIWFQDPVVCRATDITAYGYTPGTCPVAEEVGRGIVTIPLDVPSPYADRFM
QNVENLCRELQRLPRA

Sequences:

>Translated_416_residues
MDDARLAVLQKRVAAGEEEGCGSAYAQAFCAALGGGYALPTASARMALHALLRHYGLRDGDEVLVTGFTCSVVLNAILRC
GAAPRFVDIDRHTLGTSPESVEAAITPRTKALIAQHTFGVPCAIDSLRALATHYHIKLIEDVAIAFGSKYQGKPLGAWGD
AAYFSTDHSKPLNSLIGGMLYTTDENLYERIFSEYQGWPHLPREKQQALLEQVRVERDNFTPARYRWHNFAALFAGCDAP
SPFLDADYTPWAVQGDYPYPAKMPTVLTTLGLEALRQWPVVADERCHWFKKISEVFYRNNCGGMIPAGFQNIGKEVVPLR
FAFCLPAVCGPLRENKGLWRAVNAFFPANWIWFQDPVVCRATDITAYGYTPGTCPVAEEVGRGIVTIPLDVPSPYADRFM
QNVENLCRELQRLPRA
>Mature_416_residues
MDDARLAVLQKRVAAGEEEGCGSAYAQAFCAALGGGYALPTASARMALHALLRHYGLRDGDEVLVTGFTCSVVLNAILRC
GAAPRFVDIDRHTLGTSPESVEAAITPRTKALIAQHTFGVPCAIDSLRALATHYHIKLIEDVAIAFGSKYQGKPLGAWGD
AAYFSTDHSKPLNSLIGGMLYTTDENLYERIFSEYQGWPHLPREKQQALLEQVRVERDNFTPARYRWHNFAALFAGCDAP
SPFLDADYTPWAVQGDYPYPAKMPTVLTTLGLEALRQWPVVADERCHWFKKISEVFYRNNCGGMIPAGFQNIGKEVVPLR
FAFCLPAVCGPLRENKGLWRAVNAFFPANWIWFQDPVVCRATDITAYGYTPGTCPVAEEVGRGIVTIPLDVPSPYADRFM
QNVENLCRELQRLPRA

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=168, Percent_Identity=41.6666666666667, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI2367285, Length=206, Percent_Identity=28.6407766990291, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: =2.6.1.87 [H]

Molecular weight: Translated: 46067; Mature: 46067

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDARLAVLQKRVAAGEEEGCGSAYAQAFCAALGGGYALPTASARMALHALLRHYGLRDG
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
DEVLVTGFTCSVVLNAILRCGAAPRFVDIDRHTLGTSPESVEAAITPRTKALIAQHTFGV
CEEEEECHHHHHHHHHHHHCCCCCCEEECCCHHCCCCCCCCEEEECCHHHHHHHHHCCCC
PCAIDSLRALATHYHIKLIEDVAIAFGSKYQGKPLGAWGDAAYFSTDHSKPLNSLIGGML
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHHCCEE
YTTDENLYERIFSEYQGWPHLPREKQQALLEQVRVERDNFTPARYRWHNFAALFAGCDAP
EECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
SPFLDADYTPWAVQGDYPYPAKMPTVLTTLGLEALRQWPVVADERCHWFKKISEVFYRNN
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
CGGMIPAGFQNIGKEVVPLRFAFCLPAVCGPLRENKGLWRAVNAFFPANWIWFQDPVVCR
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCEEEE
ATDITAYGYTPGTCPVAEEVGRGIVTIPLDVPSPYADRFMQNVENLCRELQRLPRA
EEEEEEECCCCCCCCHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDDARLAVLQKRVAAGEEEGCGSAYAQAFCAALGGGYALPTASARMALHALLRHYGLRDG
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
DEVLVTGFTCSVVLNAILRCGAAPRFVDIDRHTLGTSPESVEAAITPRTKALIAQHTFGV
CEEEEECHHHHHHHHHHHHCCCCCCEEECCCHHCCCCCCCCEEEECCHHHHHHHHHCCCC
PCAIDSLRALATHYHIKLIEDVAIAFGSKYQGKPLGAWGDAAYFSTDHSKPLNSLIGGML
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHHCCEE
YTTDENLYERIFSEYQGWPHLPREKQQALLEQVRVERDNFTPARYRWHNFAALFAGCDAP
EECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCC
SPFLDADYTPWAVQGDYPYPAKMPTVLTTLGLEALRQWPVVADERCHWFKKISEVFYRNN
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
CGGMIPAGFQNIGKEVVPLRFAFCLPAVCGPLRENKGLWRAVNAFFPANWIWFQDPVVCR
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCEEEE
ATDITAYGYTPGTCPVAEEVGRGIVTIPLDVPSPYADRFMQNVENLCRELQRLPRA
EEEEEEECCCCCCCCHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA