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The map label for this gene is crp [C]

Identifier: 220903662

GI number: 220903662

Start: 467452

End: 468129

Strand: Reverse

Name: crp [C]

Synonym: Ddes_0383

Alternate gene names: 220903662

Gene position: 468129-467452 (Counterclockwise)

Preceding gene: 220903663

Following gene: 220903661

Centisome position: 16.29

GC content: 56.78

Gene sequence:

>678_bases
ATGAAATTCAGCAACATCAATCTTCTGGATGAACTTTCACGGCCGGAATTCGCCCCGTTGCTGGCCGCTTTTCATGAGCG
GCTCTGCCCCCGGCAGTCCATTATCTTCACTCCCCGCTATGACGATCATCTCTCTGATCAGGAGCCGCAGAAACAGGAAA
GTTTTGTTTTTATCGTCAAGTCCGGCCTTGTCCGCGTTTACCTGTCGTGCGAAGAACGCGAGTTCACCATCGGCTTTCTG
AAACCCGGCGATCTTTTTGTCAGCCATTCCAACGCACTGGTGCAGGCCGTGGATGATTCTGCCATCCTTTTGCTGGATAC
GCCCACCTTTAACAGGGGCATGATATCCATGCCGGAATTCACCATGCCCATTGTGCGCGTTCTGGGCGGCATGCTGAAAA
GCTGCTTCAGTATTATTGACGGTCTTGCCCTGCGCGATGTCACCGTGCGGCTGGCGCGCCTGCTCACAGACCTGCCCCGT
GAAGAGGACGGGCAAACGCCCGGCAGCCTTATCCGCCTGCCCCTTTCGGGTGAAAAGCTGGCCCAGAGCCTCGGCACATC
ACGCCAGACCATCTCCACCCTGCTCACAGACTTTACCCGGCTCGGCATTCTGCACAAGGAACAACGCGGCCTGTATCGCA
TACTGGACGAAGAGCGCCTGCGTGAGCTGCTGCGCTGA

Upstream 100 bases:

>100_bases
CATATGCGGTCCCTTTCCGGGGAGCCCGCAGTTGACAGACCGTGCGCAACCCCTATGCTTTTCATGTGGGTGCAGACAAA
CGCTTTGAAAAGAGGGCAAC

Downstream 100 bases:

>100_bases
CCGTGTTTTTTCACGGCCTGGTTTTTTGTCAGCCAGCCGACAGACAAAATGCCCGTTCCATGCCAGATTGTTGTAAATGA
CATGCGCCCGGGCGCACACC

Product: putative Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Carbon Monoxide Dehydrogenase CooA Protein

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKFSNINLLDELSRPEFAPLLAAFHERLCPRQSIIFTPRYDDHLSDQEPQKQESFVFIVKSGLVRVYLSCEEREFTIGFL
KPGDLFVSHSNALVQAVDDSAILLLDTPTFNRGMISMPEFTMPIVRVLGGMLKSCFSIIDGLALRDVTVRLARLLTDLPR
EEDGQTPGSLIRLPLSGEKLAQSLGTSRQTISTLLTDFTRLGILHKEQRGLYRILDEERLRELLR

Sequences:

>Translated_225_residues
MKFSNINLLDELSRPEFAPLLAAFHERLCPRQSIIFTPRYDDHLSDQEPQKQESFVFIVKSGLVRVYLSCEEREFTIGFL
KPGDLFVSHSNALVQAVDDSAILLLDTPTFNRGMISMPEFTMPIVRVLGGMLKSCFSIIDGLALRDVTVRLARLLTDLPR
EEDGQTPGSLIRLPLSGEKLAQSLGTSRQTISTLLTDFTRLGILHKEQRGLYRILDEERLRELLR
>Mature_225_residues
MKFSNINLLDELSRPEFAPLLAAFHERLCPRQSIIFTPRYDDHLSDQEPQKQESFVFIVKSGLVRVYLSCEEREFTIGFL
KPGDLFVSHSNALVQAVDDSAILLLDTPTFNRGMISMPEFTMPIVRVLGGMLKSCFSIIDGLALRDVTVRLARLLTDLPR
EEDGQTPGSLIRLPLSGEKLAQSLGTSRQTISTLLTDFTRLGILHKEQRGLYRILDEERLRELLR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25533; Mature: 25533

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSNINLLDELSRPEFAPLLAAFHERLCPRQSIIFTPRYDDHLSDQEPQKQESFVFIVK
CCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHEEEEEE
SGLVRVYLSCEEREFTIGFLKPGDLFVSHSNALVQAVDDSAILLLDTPTFNRGMISMPEF
CCEEEEEEEECCCEEEEEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCHH
TMPIVRVLGGMLKSCFSIIDGLALRDVTVRLARLLTDLPREEDGQTPGSLIRLPLSGEKL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHH
AQSLGTSRQTISTLLTDFTRLGILHKEQRGLYRILDEERLRELLR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKFSNINLLDELSRPEFAPLLAAFHERLCPRQSIIFTPRYDDHLSDQEPQKQESFVFIVK
CCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHEEEEEE
SGLVRVYLSCEEREFTIGFLKPGDLFVSHSNALVQAVDDSAILLLDTPTFNRGMISMPEF
CCEEEEEEEECCCEEEEEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCCHH
TMPIVRVLGGMLKSCFSIIDGLALRDVTVRLARLLTDLPREEDGQTPGSLIRLPLSGEKL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHH
AQSLGTSRQTISTLLTDFTRLGILHKEQRGLYRILDEERLRELLR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA