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The map label for this gene is yacO [H]

Identifier: 220903658

GI number: 220903658

Start: 455969

End: 456775

Strand: Reverse

Name: yacO [H]

Synonym: Ddes_0379

Alternate gene names: 220903658

Gene position: 456775-455969 (Counterclockwise)

Preceding gene: 220903660

Following gene: 220903649

Centisome position: 15.9

GC content: 66.29

Gene sequence:

>807_bases
ATGCATATACAATCTGAAGAAGCCCCGCTTCTGCCGGGACTCAAGCCCGTGCTGGAGCTGCTGTCCAGCGACCCGCAGCG
TGTTGACTGCGTATTCTGCAAGAAAGGGCTTCGCAGCCCCGAAGCCCGCGAGGTGCAAGACCTCTGCCGGAAAAATGATA
TCCGCTTCACGCTGGTGGAACAGGCCGCGCTTGACCGGCTGTGCCGCCCCGGCGGTCCCAGGCGCGGCGATGCGCGGGAA
GCCGGGCGTGACGCCGTGGCCCATCAGGGAGTGGTGGCCCGGCTGGCGGCGACCAGCTTTTGTGAGCTGGAGCATATCTT
TGCAGCCGTGGAACAGGCCCCTCTGCCCATAATCCTGGCCCTTGACCAGGTACAGGACCCCGGCAACGTGGGTACGCTCT
GCCGCACCCTGTACGCCCTGGGGGGCGCGGGCATTATCCTGCCGCGCCACAACAGCGCCTACCTTGGCCCTGCCGCCCGG
CGCTCCGCTGCTGGTGCGCTGGAGCATCTGCCCGTAGCGCGCGTGACCAATCTGGGGCATGCGCTGGACAGCGCCGAAGA
AGCGGGCCTGACGATTTACGGTGCCGGAGGCCAGAACGGGCCTGCCAGTGTGGACGCTTTTGCCGAGCCTGTGCGCCTGC
CTGCCGTTCTGGTACTGGGCAATGAAGAAAAAGGCCTGCGCCCGGGCATTGTCAAACGGTGCGCGCACATGCTGCGCATA
CCGCTGGCGCGGTCTTTCGATTCGCTCAACGTGGCCCAGGCCGGGGCCATCCTGCTGGGCCTGACCGCCGCGCGGCTCAA
ACCCTAA

Upstream 100 bases:

>100_bases
GGAAGGTGCGTACACAGCCGCATGGCCGTGAACGCCCGTTGTATCTATATTTTTAGCCCGGCAGCCAGTGGCCGCCGTTT
GCCCCCGCGCGGAGGCGCGC

Downstream 100 bases:

>100_bases
AACCCGCCCGACCTGACGGCCGCCGGCAGCGCCCGCCAGCCCTGATGCGCCTGCGGCCCTCACCGCGCCGCGCAGGGGGA
CTGCACCCACTGTAGCGGTC

Product: TrmH family RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MHIQSEEAPLLPGLKPVLELLSSDPQRVDCVFCKKGLRSPEAREVQDLCRKNDIRFTLVEQAALDRLCRPGGPRRGDARE
AGRDAVAHQGVVARLAATSFCELEHIFAAVEQAPLPIILALDQVQDPGNVGTLCRTLYALGGAGIILPRHNSAYLGPAAR
RSAAGALEHLPVARVTNLGHALDSAEEAGLTIYGAGGQNGPASVDAFAEPVRLPAVLVLGNEEKGLRPGIVKRCAHMLRI
PLARSFDSLNVAQAGAILLGLTAARLKP

Sequences:

>Translated_268_residues
MHIQSEEAPLLPGLKPVLELLSSDPQRVDCVFCKKGLRSPEAREVQDLCRKNDIRFTLVEQAALDRLCRPGGPRRGDARE
AGRDAVAHQGVVARLAATSFCELEHIFAAVEQAPLPIILALDQVQDPGNVGTLCRTLYALGGAGIILPRHNSAYLGPAAR
RSAAGALEHLPVARVTNLGHALDSAEEAGLTIYGAGGQNGPASVDAFAEPVRLPAVLVLGNEEKGLRPGIVKRCAHMLRI
PLARSFDSLNVAQAGAILLGLTAARLKP
>Mature_268_residues
MHIQSEEAPLLPGLKPVLELLSSDPQRVDCVFCKKGLRSPEAREVQDLCRKNDIRFTLVEQAALDRLCRPGGPRRGDARE
AGRDAVAHQGVVARLAATSFCELEHIFAAVEQAPLPIILALDQVQDPGNVGTLCRTLYALGGAGIILPRHNSAYLGPAAR
RSAAGALEHLPVARVTNLGHALDSAEEAGLTIYGAGGQNGPASVDAFAEPVRLPAVLVLGNEEKGLRPGIVKRCAHMLRI
PLARSFDSLNVAQAGAILLGLTAARLKP

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=160, Percent_Identity=32.5, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790623, Length=255, Percent_Identity=28.6274509803922, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555908, Length=264, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324775, Length=166, Percent_Identity=31.3253012048193, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28376; Mature: 28376

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIQSEEAPLLPGLKPVLELLSSDPQRVDCVFCKKGLRSPEAREVQDLCRKNDIRFTLVE
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHH
QAALDRLCRPGGPRRGDAREAGRDAVAHQGVVARLAATSFCELEHIFAAVEQAPLPIILA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LDQVQDPGNVGTLCRTLYALGGAGIILPRHNSAYLGPAARRSAAGALEHLPVARVTNLGH
ECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
ALDSAEEAGLTIYGAGGQNGPASVDAFAEPVRLPAVLVLGNEEKGLRPGIVKRCAHMLRI
HHCCHHHCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
PLARSFDSLNVAQAGAILLGLTAARLKP
HHHHCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHIQSEEAPLLPGLKPVLELLSSDPQRVDCVFCKKGLRSPEAREVQDLCRKNDIRFTLVE
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHH
QAALDRLCRPGGPRRGDAREAGRDAVAHQGVVARLAATSFCELEHIFAAVEQAPLPIILA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LDQVQDPGNVGTLCRTLYALGGAGIILPRHNSAYLGPAARRSAAGALEHLPVARVTNLGH
ECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
ALDSAEEAGLTIYGAGGQNGPASVDAFAEPVRLPAVLVLGNEEKGLRPGIVKRCAHMLRI
HHCCHHHCCEEEEECCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
PLARSFDSLNVAQAGAILLGLTAARLKP
HHHHCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]