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The map label for this gene is dcrA [H]

Identifier: 220903581

GI number: 220903581

Start: 363705

End: 365462

Strand: Direct

Name: dcrA [H]

Synonym: Ddes_0300

Alternate gene names: 220903581

Gene position: 363705-365462 (Clockwise)

Preceding gene: 220903580

Following gene: 220903582

Centisome position: 12.66

GC content: 59.1

Gene sequence:

>1758_bases
ATGTTCTGGAAAAATCTTTCCATCGGAAAGAAGTTGTGTTTTGGCTTCGGCATCAGCCTGGCAGGCATGATCTGTTTTGC
CGTGGTGGCCTGGTATGCGTCCAACCTGGTCATGACCATGGCTGACAGCGCGTTGCAAAAACAGAGCAATGCCCTGGTTT
TTGCCATGCGCGAGGCCGATCATCTGCACTGGAAAGAACGGGTCAGCAGTTTTGTCGCCATGCCGTCTGCGGACGGCAAG
CTTGACGTGCAGAAAGACGGCCACAAATGCCTTTTCGGCCAGTGGTTTTATAATGGTGGCCGTGAAGAGGTGGAAGCCAT
TCTGCCCGGCACGTCGAGCTATTTTAAAAGCATGGAGGCCGACCACCTGGACCTGCACCGCAGCGCTTCGGATATTGAGC
GGCTTGTGCAGGCCGGTGACCTGCAGGGGGCCAGAGCGCATTTTAATGCCGTTACGCTGGCCAAGTCATCGGCGGTGGTG
GAAACCCTCGCGCAGCTGCGTAAAATGATGTTGCATGCCGCCGAAGCTGACAGGGAAAGCTACAAGCAGATCATGGCCCG
TGAGGAATATGTGGTTGTTGCCCTGCTGCTGGTCGTGCTGGCGGGCATGCTTGTTTCCGGCGTAGCCATTACGCGGTCTA
TCCGCAATCCGTTACGCGGGCTTGTGGACAAATCGGCCGAAGTGGTGGCGGGAAATCTGGATGTGGACCTGCGTTTGCGG
CGTCAGGATGAAATCGGCGCGCTGTCGCGTGCCTTGGGCGCCTTGCTGGATAACCTCAAGCTCAAACTGGCCGAAAACGA
GAAAAAGTCTGAAGAAGCGCAGGCCAGCGCTGAGCATACCCGCAATGCTCTTAAAGATGCAGAGGAAAAAGAAGCGCGCA
TTGCCAGCCTGCTGGGCGATATGAACGCCATCGCCACGCAGGCCGACGTTATTGCCGCCGACCTTGCCGACCACTCCGCC
ACCCTGGCCCAGCGCGTGGAAACTGTCTACCGGGGCAGCGAAGACCAGCATGATCTCATGCGCAGCAGCCTTGATGACCT
GGAGCAGCTTGCCTCCGCCGCCGGCGAAATTGCCGTCAGCGCGGAGCATTCGGCCCACGGGGCGCGCAGTTCCAGGGAGC
ATGCCGGCAGCGGTGTGGATGTGGTGACCCGCTGCGCCCAGGCCATCAGCCGGGTCAACGATCTTGCGGCCAAGCAGAAC
GGGCAGGTTGCCGAACTGGGCGAAATGGCCCAGGGCATTACCGGCATTATGAGTGTTATTACCGATATTGCTGACCAGAC
CAACCTGCTGGCCCTGAACGCCGCCATTGAAGCAGCCCGGGCAGGTGAGGCCGGACGCGGTTTTTCCGTGGTTGCCGATG
AGGTGAGAAAACTGGCAGAAAAAACGGTCACCGCTACTCAGGCCGTAGGTGCAAAAATCACCGGCATTCAGGAATCCATT
CATGCCAGTGTGGCCTTTATGGGGCAGACCAGCGAGGCTGTGCATGAATCCAATGATCTTGCGCAGCAGTCCGGAGCGGC
GCTTTCGCAGATTCTGGATCTGGCTGCCGCCAACGTGGACAGCGCCGCCGGCATGGCCGTGGCCGCACAGCAGCAAAGCG
ATACCGTGGTGCATGTGGCGCAGGGCATGAAAAATGTGCAGGACATTGCTGAGTCCAGCCGTGCAGCCATGAGTGAAGCC
GACCGCCAGGTGCGGGCTGTGGCCAAGATGGCCGGCGAACTGCGGGAACTTATCGACAGGCTTAAAAGCAGGGCCTGA

Upstream 100 bases:

>100_bases
ATTTTCCGGCGGCACGGTTTTGCCGCCAAAATTTCGGCAATGTGTTAAAAACAGGTTATATTCCTGTAGTTATAGATAGC
TAATATTTCCAGGAGGAATC

Downstream 100 bases:

>100_bases
TTTTACAGACGGCGTGCTTTTGTAAGCGCCCTGCCAGACGGAAAATGTTTTTCCGTCTGGCAGGGCGTTTTTGCCATATG
CGGCTCCGCAAGCACGCGAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MFWKNLSIGKKLCFGFGISLAGMICFAVVAWYASNLVMTMADSALQKQSNALVFAMREADHLHWKERVSSFVAMPSADGK
LDVQKDGHKCLFGQWFYNGGREEVEAILPGTSSYFKSMEADHLDLHRSASDIERLVQAGDLQGARAHFNAVTLAKSSAVV
ETLAQLRKMMLHAAEADRESYKQIMAREEYVVVALLLVVLAGMLVSGVAITRSIRNPLRGLVDKSAEVVAGNLDVDLRLR
RQDEIGALSRALGALLDNLKLKLAENEKKSEEAQASAEHTRNALKDAEEKEARIASLLGDMNAIATQADVIAADLADHSA
TLAQRVETVYRGSEDQHDLMRSSLDDLEQLASAAGEIAVSAEHSAHGARSSREHAGSGVDVVTRCAQAISRVNDLAAKQN
GQVAELGEMAQGITGIMSVITDIADQTNLLALNAAIEAARAGEAGRGFSVVADEVRKLAEKTVTATQAVGAKITGIQESI
HASVAFMGQTSEAVHESNDLAQQSGAALSQILDLAAANVDSAAGMAVAAQQQSDTVVHVAQGMKNVQDIAESSRAAMSEA
DRQVRAVAKMAGELRELIDRLKSRA

Sequences:

>Translated_585_residues
MFWKNLSIGKKLCFGFGISLAGMICFAVVAWYASNLVMTMADSALQKQSNALVFAMREADHLHWKERVSSFVAMPSADGK
LDVQKDGHKCLFGQWFYNGGREEVEAILPGTSSYFKSMEADHLDLHRSASDIERLVQAGDLQGARAHFNAVTLAKSSAVV
ETLAQLRKMMLHAAEADRESYKQIMAREEYVVVALLLVVLAGMLVSGVAITRSIRNPLRGLVDKSAEVVAGNLDVDLRLR
RQDEIGALSRALGALLDNLKLKLAENEKKSEEAQASAEHTRNALKDAEEKEARIASLLGDMNAIATQADVIAADLADHSA
TLAQRVETVYRGSEDQHDLMRSSLDDLEQLASAAGEIAVSAEHSAHGARSSREHAGSGVDVVTRCAQAISRVNDLAAKQN
GQVAELGEMAQGITGIMSVITDIADQTNLLALNAAIEAARAGEAGRGFSVVADEVRKLAEKTVTATQAVGAKITGIQESI
HASVAFMGQTSEAVHESNDLAQQSGAALSQILDLAAANVDSAAGMAVAAQQQSDTVVHVAQGMKNVQDIAESSRAAMSEA
DRQVRAVAKMAGELRELIDRLKSRA
>Mature_585_residues
MFWKNLSIGKKLCFGFGISLAGMICFAVVAWYASNLVMTMADSALQKQSNALVFAMREADHLHWKERVSSFVAMPSADGK
LDVQKDGHKCLFGQWFYNGGREEVEAILPGTSSYFKSMEADHLDLHRSASDIERLVQAGDLQGARAHFNAVTLAKSSAVV
ETLAQLRKMMLHAAEADRESYKQIMAREEYVVVALLLVVLAGMLVSGVAITRSIRNPLRGLVDKSAEVVAGNLDVDLRLR
RQDEIGALSRALGALLDNLKLKLAENEKKSEEAQASAEHTRNALKDAEEKEARIASLLGDMNAIATQADVIAADLADHSA
TLAQRVETVYRGSEDQHDLMRSSLDDLEQLASAAGEIAVSAEHSAHGARSSREHAGSGVDVVTRCAQAISRVNDLAAKQN
GQVAELGEMAQGITGIMSVITDIADQTNLLALNAAIEAARAGEAGRGFSVVADEVRKLAEKTVTATQAVGAKITGIQESI
HASVAFMGQTSEAVHESNDLAQQSGAALSQILDLAAANVDSAAGMAVAAQQQSDTVVHVAQGMKNVQDIAESSRAAMSEA
DRQVRAVAKMAGELRELIDRLKSRA

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=294, Percent_Identity=28.9115646258503, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787690, Length=276, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788194, Length=393, Percent_Identity=26.7175572519084, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788195, Length=127, Percent_Identity=41.7322834645669, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789453, Length=152, Percent_Identity=30.9210526315789, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 62479; Mature: 62479

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWKNLSIGKKLCFGFGISLAGMICFAVVAWYASNLVMTMADSALQKQSNALVFAMREAD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
HLHWKERVSSFVAMPSADGKLDVQKDGHKCLFGQWFYNGGREEVEAILPGTSSYFKSMEA
HHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEHHHHHCCCHHHHHHHCCCCHHHHHCCCC
DHLDLHRSASDIERLVQAGDLQGARAHFNAVTLAKSSAVVETLAQLRKMMLHAAEADRES
CHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YKQIMAREEYVVVALLLVVLAGMLVSGVAITRSIRNPLRGLVDKSAEVVAGNLDVDLRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEC
RQDEIGALSRALGALLDNLKLKLAENEKKSEEAQASAEHTRNALKDAEEKEARIASLLGD
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNAIATQADVIAADLADHSATLAQRVETVYRGSEDQHDLMRSSLDDLEQLASAAGEIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE
AEHSAHGARSSREHAGSGVDVVTRCAQAISRVNDLAAKQNGQVAELGEMAQGITGIMSVI
CCHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TDIADQTNLLALNAAIEAARAGEAGRGFSVVADEVRKLAEKTVTATQAVGAKITGIQESI
HHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HASVAFMGQTSEAVHESNDLAQQSGAALSQILDLAAANVDSAAGMAVAAQQQSDTVVHVA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHH
QGMKNVQDIAESSRAAMSEADRQVRAVAKMAGELRELIDRLKSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFWKNLSIGKKLCFGFGISLAGMICFAVVAWYASNLVMTMADSALQKQSNALVFAMREAD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHH
HLHWKERVSSFVAMPSADGKLDVQKDGHKCLFGQWFYNGGREEVEAILPGTSSYFKSMEA
HHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEHHHHHCCCHHHHHHHCCCCHHHHHCCCC
DHLDLHRSASDIERLVQAGDLQGARAHFNAVTLAKSSAVVETLAQLRKMMLHAAEADRES
CHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
YKQIMAREEYVVVALLLVVLAGMLVSGVAITRSIRNPLRGLVDKSAEVVAGNLDVDLRLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEC
RQDEIGALSRALGALLDNLKLKLAENEKKSEEAQASAEHTRNALKDAEEKEARIASLLGD
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNAIATQADVIAADLADHSATLAQRVETVYRGSEDQHDLMRSSLDDLEQLASAAGEIAVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEE
AEHSAHGARSSREHAGSGVDVVTRCAQAISRVNDLAAKQNGQVAELGEMAQGITGIMSVI
CCHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TDIADQTNLLALNAAIEAARAGEAGRGFSVVADEVRKLAEKTVTATQAVGAKITGIQESI
HHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HASVAFMGQTSEAVHESNDLAQQSGAALSQILDLAAANVDSAAGMAVAAQQQSDTVVHVA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHHHH
QGMKNVQDIAESSRAAMSEADRQVRAVAKMAGELRELIDRLKSRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]