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The map label for this gene is smvA [H]

Identifier: 220903478

GI number: 220903478

Start: 245911

End: 247482

Strand: Reverse

Name: smvA [H]

Synonym: Ddes_0194

Alternate gene names: 220903478

Gene position: 247482-245911 (Counterclockwise)

Preceding gene: 220903479

Following gene: 220903477

Centisome position: 8.61

GC content: 63.17

Gene sequence:

>1572_bases
ATGAACAAGGACAATCTCAATACAGGCAACGGGCAGCCCACGGATACTTCCGGCAAGCCCGGCCCGTCCAGAGCTGCCCG
CCGGCGCATACTGCTGGCCGTTATGGTGGCATGGCTGCCCATAGCCACGGACATGACCATCCTTCACATCGCCGTCCCCT
CCCTGACCCTCGCCCTGAAGGCCACGGGAACGGAGATACTCTGGATCATAGACATTTACCCCCTGATCGTGGCCAGCCTG
CTGGTTCCTATGGGTACACGGAGCGACAGCGTCGGGCCACGCAAGCTCCTGCTGGCCGGGCTGGTCATCTTTATGGCCGC
ATCGCTGGCAGCGGCTTTCGCGCCCACGGCCAGAGCACTCATCGCAGCCAGAGCCTGTCTGGCCCTGGGTGCGTCAATGA
TCGTACCCAGCGTGCTCGCCATCATACGGATCACCTTTGACGACTGGAAGGAACGGGCAATGGCCCTGGGCATCTGGGGC
ACTGTAAGTACCGTGAGCGCGGCCATGGGGCCTCTGGTGGGCGGCCTGCTGCTTGAACATTTCTGGTGGGGTTCAGTCTT
TCTTATCAATGTGCCGCTTATCCTGATCATTCTGCCCCTGGCCGCCGCGATCCTGCCCAGGCCCCGTCCCGGCCCCCGAA
AGCCGTGGCCCATCGGGCAGGCCCTGACACTGGCTGCGGGCCTTATGTCCACGGTATACGCGGTCAAAACGATCTTCAGG
CAGGACAGTTCCCTTCTGCTTTGCGGTATTGCGCTGCTGTGCGGCATTGGTCTGATGGCGCTCTTCATCCGAAAACAGAT
GACAGCGCGCACCCCCATGCTGGATCTCGACCTGTTCAGGCTGCCCGCCATTCGCGTGGGCCTGGTGGCCGCTCTTGTGG
TTTCTGGCGCTCTTGCAGGCGTGGAACTGACCATTGCCCAGGAATTGCAGTTCGTTCTCGGCCGCACGCCGCTACAGGCG
GGCATATTCATGCTGCCCATCATGGCCGCCTCTGCCGTGGGCGGGCCTCTGGCAGGCAGGCTGGTCGTCATGGCTGGCCT
GCGAAACGTGTTCACGGTATCCCTGCTAGCGGCCGGAGGCAGCCTTGCCGGGCTGGGCCTTGCCAGCTTTCATGATGCGG
GCTGGCTTGTGGCAGCCTATATGGTAGTGCTGGGCCTGTCGCTCAGCATCGGCCTGACTGCATCCTCCATAGCCATCATG
GGCAGCGTGCCGCCGGAAAAAGGTGGCGCGGCCGGGTCCATCGAAGCTCTGGGCTACGATCTGGGCGCGGGATTGGGCAT
CACAGCCTTTGGCGTATTACTGGCGGCCAATTACAGCGCTGCCTTGCGGCTGCCCGAAAACCTGCGCCAGCATCTGCCGC
GCAGCGCCCTGGACTCCATCAGCGACACAATGGTGGCAGCGGAGCTTACCGGCGGTGAAAAGGGACAGGCCATTGTCGAG
GCAGGGCAGGCGGCTTTTACCGCCGCGCACAGTACGGTGCTGCTGTCAGCGGCACTGCTGGTCTGCCTGCTGGCTCTGTG
GGTTTTCAGCAGTCTGCGGCGCTATCGCGGTGAAGAGCAACGCCGGGGCTGA

Upstream 100 bases:

>100_bases
AAAGAATAGATGGGCAGCAAAACATGAAAGAATACCGCTGAAATTGCGACAGCGGACAACATTCGGCAACATTGGCGCAA
CAAAGATTTTCAATTATTTT

Downstream 100 bases:

>100_bases
TACCAGCCCCGCGTATTGCGGGGCTGGATTTTGTCCGGCGTTTCGCCACATGTCACGCTTCTGACGCGCCCGATACATAA
CAGGCTGTTCTTTTTGGCAA

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MNKDNLNTGNGQPTDTSGKPGPSRAARRRILLAVMVAWLPIATDMTILHIAVPSLTLALKATGTEILWIIDIYPLIVASL
LVPMGTRSDSVGPRKLLLAGLVIFMAASLAAAFAPTARALIAARACLALGASMIVPSVLAIIRITFDDWKERAMALGIWG
TVSTVSAAMGPLVGGLLLEHFWWGSVFLINVPLILIILPLAAAILPRPRPGPRKPWPIGQALTLAAGLMSTVYAVKTIFR
QDSSLLLCGIALLCGIGLMALFIRKQMTARTPMLDLDLFRLPAIRVGLVAALVVSGALAGVELTIAQELQFVLGRTPLQA
GIFMLPIMAASAVGGPLAGRLVVMAGLRNVFTVSLLAAGGSLAGLGLASFHDAGWLVAAYMVVLGLSLSIGLTASSIAIM
GSVPPEKGGAAGSIEALGYDLGAGLGITAFGVLLAANYSAALRLPENLRQHLPRSALDSISDTMVAAELTGGEKGQAIVE
AGQAAFTAAHSTVLLSAALLVCLLALWVFSSLRRYRGEEQRRG

Sequences:

>Translated_523_residues
MNKDNLNTGNGQPTDTSGKPGPSRAARRRILLAVMVAWLPIATDMTILHIAVPSLTLALKATGTEILWIIDIYPLIVASL
LVPMGTRSDSVGPRKLLLAGLVIFMAASLAAAFAPTARALIAARACLALGASMIVPSVLAIIRITFDDWKERAMALGIWG
TVSTVSAAMGPLVGGLLLEHFWWGSVFLINVPLILIILPLAAAILPRPRPGPRKPWPIGQALTLAAGLMSTVYAVKTIFR
QDSSLLLCGIALLCGIGLMALFIRKQMTARTPMLDLDLFRLPAIRVGLVAALVVSGALAGVELTIAQELQFVLGRTPLQA
GIFMLPIMAASAVGGPLAGRLVVMAGLRNVFTVSLLAAGGSLAGLGLASFHDAGWLVAAYMVVLGLSLSIGLTASSIAIM
GSVPPEKGGAAGSIEALGYDLGAGLGITAFGVLLAANYSAALRLPENLRQHLPRSALDSISDTMVAAELTGGEKGQAIVE
AGQAAFTAAHSTVLLSAALLVCLLALWVFSSLRRYRGEEQRRG
>Mature_523_residues
MNKDNLNTGNGQPTDTSGKPGPSRAARRRILLAVMVAWLPIATDMTILHIAVPSLTLALKATGTEILWIIDIYPLIVASL
LVPMGTRSDSVGPRKLLLAGLVIFMAASLAAAFAPTARALIAARACLALGASMIVPSVLAIIRITFDDWKERAMALGIWG
TVSTVSAAMGPLVGGLLLEHFWWGSVFLINVPLILIILPLAAAILPRPRPGPRKPWPIGQALTLAAGLMSTVYAVKTIFR
QDSSLLLCGIALLCGIGLMALFIRKQMTARTPMLDLDLFRLPAIRVGLVAALVVSGALAGVELTIAQELQFVLGRTPLQA
GIFMLPIMAASAVGGPLAGRLVVMAGLRNVFTVSLLAAGGSLAGLGLASFHDAGWLVAAYMVVLGLSLSIGLTASSIAIM
GSVPPEKGGAAGSIEALGYDLGAGLGITAFGVLLAANYSAALRLPENLRQHLPRSALDSISDTMVAAELTGGEKGQAIVE
AGQAAFTAAHSTVLLSAALLVCLLALWVFSSLRRYRGEEQRRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=423, Percent_Identity=28.8416075650118, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788710, Length=318, Percent_Identity=26.4150943396226, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790195, Length=393, Percent_Identity=23.4096692111959, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789042, Length=482, Percent_Identity=21.9917012448133, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788392, Length=404, Percent_Identity=25.990099009901, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 54414; Mature: 54414

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDNLNTGNGQPTDTSGKPGPSRAARRRILLAVMVAWLPIATDMTILHIAVPSLTLALK
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHEEEEE
ATGTEILWIIDIYPLIVASLLVPMGTRSDSVGPRKLLLAGLVIFMAASLAAAFAPTARAL
ECCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAARACLALGASMIVPSVLAIIRITFDDWKERAMALGIWGTVSTVSAAMGPLVGGLLLEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHH
FWWGSVFLINVPLILIILPLAAAILPRPRPGPRKPWPIGQALTLAAGLMSTVYAVKTIFR
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QDSSLLLCGIALLCGIGLMALFIRKQMTARTPMLDLDLFRLPAIRVGLVAALVVSGALAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
VELTIAQELQFVLGRTPLQAGIFMLPIMAASAVGGPLAGRLVVMAGLRNVFTVSLLAAGG
EEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SLAGLGLASFHDAGWLVAAYMVVLGLSLSIGLTASSIAIMGSVPPEKGGAAGSIEALGYD
CHHHCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCHHHHHHH
LGAGLGITAFGVLLAANYSAALRLPENLRQHLPRSALDSISDTMVAAELTGGEKGQAIVE
HCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHCCHHHHHHHHHHHEEEECCCCCCCHHHHH
AGQAAFTAAHSTVLLSAALLVCLLALWVFSSLRRYRGEEQRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MNKDNLNTGNGQPTDTSGKPGPSRAARRRILLAVMVAWLPIATDMTILHIAVPSLTLALK
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHEEEEE
ATGTEILWIIDIYPLIVASLLVPMGTRSDSVGPRKLLLAGLVIFMAASLAAAFAPTARAL
ECCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAARACLALGASMIVPSVLAIIRITFDDWKERAMALGIWGTVSTVSAAMGPLVGGLLLEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHH
FWWGSVFLINVPLILIILPLAAAILPRPRPGPRKPWPIGQALTLAAGLMSTVYAVKTIFR
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QDSSLLLCGIALLCGIGLMALFIRKQMTARTPMLDLDLFRLPAIRVGLVAALVVSGALAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
VELTIAQELQFVLGRTPLQAGIFMLPIMAASAVGGPLAGRLVVMAGLRNVFTVSLLAAGG
EEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SLAGLGLASFHDAGWLVAAYMVVLGLSLSIGLTASSIAIMGSVPPEKGGAAGSIEALGYD
CHHHCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCHHHHHHH
LGAGLGITAFGVLLAANYSAALRLPENLRQHLPRSALDSISDTMVAAELTGGEKGQAIVE
HCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHCCHHHHHHHHHHHEEEECCCCCCCHHHHH
AGQAAFTAAHSTVLLSAALLVCLLALWVFSSLRRYRGEEQRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7926834; 11677609 [H]