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The map label for this gene is dcrA [H]

Identifier: 220903405

GI number: 220903405

Start: 153006

End: 154763

Strand: Direct

Name: dcrA [H]

Synonym: Ddes_0119

Alternate gene names: 220903405

Gene position: 153006-154763 (Clockwise)

Preceding gene: 220903404

Following gene: 220903406

Centisome position: 5.32

GC content: 57.57

Gene sequence:

>1758_bases
ATGAATTCATTTTCTTTGCGCGGAAAGTTCATCTTGACGATAACCATAGGTGCTGTGGCTCTTGCTGCCATGTTCTCCTT
TTCTCTTGACGCTGTTTCTACGCTTGACCGCTCGTTCTTGCAGATGCGGAATGTGGATGTGGTGGGCAAGATCACCAGCC
TTGAAATAGGAAAGGACATAAACTATGTGAGCCGCCTTACCCGTGATGCCATGCTGGGCGGCAACATTGAAAAGGATATC
AAGCAGCAGAGCGACATCGCCAAGCGTAACGAAGAGCGCTTCCAGCAGCTTGCCGCCATGCCTTTCAGCGGTGAGGAAAA
AAAGATTATTGACGAGGCCCGTACGGCCGCCATCAACTTTATCGCCAATGGCCGCGACGTTCTTTTGCCGCTGCAGTCCG
TTCCTGTGGACGAACGTTACAAGGGGTACAAAGAATACGCCAAGATGGTGACCCCCTATGCCATGGCCTATCGCGATCAG
GGCGGTCTGTTTGACAAGGCCATGAACGCCCGTTTTGACGCCGCCATGCAGCAGATGCAGGAACAGCTTGATCACAGTCG
CACGACCATGTGGATAATACTGGCTGTTTCCATGCTGGCTATTTATGGTGTGGGTTTTGCCTCTACCAGCCGTGACCTCA
ACGTCATGCGCGAGTGTATCGCCTTTGCCGGCGAACTGGGGTCCGAGACGCTTACGCGCCGGCTTGATACCAGCAAAAGG
TCTTCCATCACGCCGCTGGCCAAGGCGCTGAATGCCACCGCGGACAATCTGGACAGCTTCAGGGCCGAAACGCTCAAGGC
CACAGCTGAAGCCCAGAAAGAGCGCGATGAGGCCCAGGGTTTCATGCTACAGGCTCAGGCAGCCAAGGAAGAAGCCGAAA
AGGCCAAGGTTGAAGGTATGCTGTACGCCGCAAGCCAGCTTGAGGCTGTGGTGCAGACGCTCAATACCACCACTGATAAT
CTTTCCAGCCTTATCCACAACGCCAATAACGGAACCACCCGTCAGGCTGACCGTATGCGCGAGACGGCCTCGGCTATGGA
GCAGATGAACGCCTCCATGCTTGAGGTGGCCCAAAGCTCCTCCCACGCGGCAAACACCGCTGACCAGACCAGAAGCAAGG
CTCAGGACGGATCGACTTCGGTTACGGAACTGCTCGACAATATCCGCGAGGTACAGCAGCAGGCCGGAGAAATGAAAGAC
GGTATGGCCGGGCTTGGGGTTCAGGCCGAGGCTATCGGCAAGGTGCTCAACGTCATTGCCGACATTGCCGACCAGACCAA
CCTGCTGGCCCTTAACGCCGCCATTGAAGCTGCGCGCGCGGGCGATGCCGGACGCGGCTTTGCCGTGGTGGCCGACGAGG
TGCGCAAGCTGGCCGAAAAAACCATGACGGCCACCAGAGAAGTGGGTGAAGCCATCGGCGGCATACAGTCGGGCACCACG
CACACCATTGACGTGGTTACCCGCACGGTTTCCCGCATTCAGGGCGCCAGCCAGCTGGCTGACCGTTCCGGTACGGCCCT
GGCGGAGATAGTGTCCATGGTCGACCTGACCACAGATCAGGTGCGCGCCATTGCCGCCGCTTCGGAAGAGCAGTCTGCGG
CCAGTTCTGAAATCAACCGCAGCCTGGATGAAGTGGACAGGATATCGGGCGAGAATGCCTCGTTCATGCATCAGTCCGCA
GATTCCATCATGGAGCTGTCCCGGCAGGCCGGCGTGCTTCAGGACCTTATCAGCCAGATGAAGCAGGGCGGCGCGTAA

Upstream 100 bases:

>100_bases
CATGTCGCCATATGACATTCTTTGGCCACTGCAGTAATGCAGAGAATATATATTTGTATACAGGAAAGAACTGTTCAACT
CTCAGCCAAGCAGTGTTACT

Downstream 100 bases:

>100_bases
CAGCTTTCGCCACAGCATATTCGTTGACATCCCCCGTCTTTTTACGGCAGCCGCGCAGGCCGCCTGAAAAGATGGGGGAT
TGCCGTTGGCTGTTCCAGGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MNSFSLRGKFILTITIGAVALAAMFSFSLDAVSTLDRSFLQMRNVDVVGKITSLEIGKDINYVSRLTRDAMLGGNIEKDI
KQQSDIAKRNEERFQQLAAMPFSGEEKKIIDEARTAAINFIANGRDVLLPLQSVPVDERYKGYKEYAKMVTPYAMAYRDQ
GGLFDKAMNARFDAAMQQMQEQLDHSRTTMWIILAVSMLAIYGVGFASTSRDLNVMRECIAFAGELGSETLTRRLDTSKR
SSITPLAKALNATADNLDSFRAETLKATAEAQKERDEAQGFMLQAQAAKEEAEKAKVEGMLYAASQLEAVVQTLNTTTDN
LSSLIHNANNGTTRQADRMRETASAMEQMNASMLEVAQSSSHAANTADQTRSKAQDGSTSVTELLDNIREVQQQAGEMKD
GMAGLGVQAEAIGKVLNVIADIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATREVGEAIGGIQSGTT
HTIDVVTRTVSRIQGASQLADRSGTALAEIVSMVDLTTDQVRAIAAASEEQSAASSEINRSLDEVDRISGENASFMHQSA
DSIMELSRQAGVLQDLISQMKQGGA

Sequences:

>Translated_585_residues
MNSFSLRGKFILTITIGAVALAAMFSFSLDAVSTLDRSFLQMRNVDVVGKITSLEIGKDINYVSRLTRDAMLGGNIEKDI
KQQSDIAKRNEERFQQLAAMPFSGEEKKIIDEARTAAINFIANGRDVLLPLQSVPVDERYKGYKEYAKMVTPYAMAYRDQ
GGLFDKAMNARFDAAMQQMQEQLDHSRTTMWIILAVSMLAIYGVGFASTSRDLNVMRECIAFAGELGSETLTRRLDTSKR
SSITPLAKALNATADNLDSFRAETLKATAEAQKERDEAQGFMLQAQAAKEEAEKAKVEGMLYAASQLEAVVQTLNTTTDN
LSSLIHNANNGTTRQADRMRETASAMEQMNASMLEVAQSSSHAANTADQTRSKAQDGSTSVTELLDNIREVQQQAGEMKD
GMAGLGVQAEAIGKVLNVIADIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATREVGEAIGGIQSGTT
HTIDVVTRTVSRIQGASQLADRSGTALAEIVSMVDLTTDQVRAIAAASEEQSAASSEINRSLDEVDRISGENASFMHQSA
DSIMELSRQAGVLQDLISQMKQGGA
>Mature_585_residues
MNSFSLRGKFILTITIGAVALAAMFSFSLDAVSTLDRSFLQMRNVDVVGKITSLEIGKDINYVSRLTRDAMLGGNIEKDI
KQQSDIAKRNEERFQQLAAMPFSGEEKKIIDEARTAAINFIANGRDVLLPLQSVPVDERYKGYKEYAKMVTPYAMAYRDQ
GGLFDKAMNARFDAAMQQMQEQLDHSRTTMWIILAVSMLAIYGVGFASTSRDLNVMRECIAFAGELGSETLTRRLDTSKR
SSITPLAKALNATADNLDSFRAETLKATAEAQKERDEAQGFMLQAQAAKEEAEKAKVEGMLYAASQLEAVVQTLNTTTDN
LSSLIHNANNGTTRQADRMRETASAMEQMNASMLEVAQSSSHAANTADQTRSKAQDGSTSVTELLDNIREVQQQAGEMKD
GMAGLGVQAEAIGKVLNVIADIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATREVGEAIGGIQSGTT
HTIDVVTRTVSRIQGASQLADRSGTALAEIVSMVDLTTDQVRAIAAASEEQSAASSEINRSLDEVDRISGENASFMHQSA
DSIMELSRQAGVLQDLISQMKQGGA

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=246, Percent_Identity=33.739837398374, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788194, Length=239, Percent_Identity=32.6359832635983, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI2367378, Length=221, Percent_Identity=35.7466063348416, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788195, Length=225, Percent_Identity=34.2222222222222, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789453, Length=270, Percent_Identity=30, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 63164; Mature: 63164

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00589 PTS_HPR_SER ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFSLRGKFILTITIGAVALAAMFSFSLDAVSTLDRSFLQMRNVDVVGKITSLEIGKDI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCCCH
NYVSRLTRDAMLGGNIEKDIKQQSDIAKRNEERFQQLAAMPFSGEEKKIIDEARTAAINF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IANGRDVLLPLQSVPVDERYKGYKEYAKMVTPYAMAYRDQGGLFDKAMNARFDAAMQQMQ
HCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
EQLDHSRTTMWIILAVSMLAIYGVGFASTSRDLNVMRECIAFAGELGSETLTRRLDTSKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
SSITPLAKALNATADNLDSFRAETLKATAEAQKERDEAQGFMLQAQAAKEEAEKAKVEGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYAASQLEAVVQTLNTTTDNLSSLIHNANNGTTRQADRMRETASAMEQMNASMLEVAQSS
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SHAANTADQTRSKAQDGSTSVTELLDNIREVQQQAGEMKDGMAGLGVQAEAIGKVLNVIA
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
DIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATREVGEAIGGIQSGTT
HHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HTIDVVTRTVSRIQGASQLADRSGTALAEIVSMVDLTTDQVRAIAAASEEQSAASSEINR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SLDEVDRISGENASFMHQSADSIMELSRQAGVLQDLISQMKQGGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSFSLRGKFILTITIGAVALAAMFSFSLDAVSTLDRSFLQMRNVDVVGKITSLEIGKDI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCCCH
NYVSRLTRDAMLGGNIEKDIKQQSDIAKRNEERFQQLAAMPFSGEEKKIIDEARTAAINF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IANGRDVLLPLQSVPVDERYKGYKEYAKMVTPYAMAYRDQGGLFDKAMNARFDAAMQQMQ
HCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
EQLDHSRTTMWIILAVSMLAIYGVGFASTSRDLNVMRECIAFAGELGSETLTRRLDTSKR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
SSITPLAKALNATADNLDSFRAETLKATAEAQKERDEAQGFMLQAQAAKEEAEKAKVEGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYAASQLEAVVQTLNTTTDNLSSLIHNANNGTTRQADRMRETASAMEQMNASMLEVAQSS
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SHAANTADQTRSKAQDGSTSVTELLDNIREVQQQAGEMKDGMAGLGVQAEAIGKVLNVIA
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
DIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATREVGEAIGGIQSGTT
HHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HTIDVVTRTVSRIQGASQLADRSGTALAEIVSMVDLTTDQVRAIAAASEEQSAASSEINR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SLDEVDRISGENASFMHQSADSIMELSRQAGVLQDLISQMKQGGA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1548224 [H]