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The map label for this gene is mcp4 [H]

Identifier: 220903372

GI number: 220903372

Start: 112349

End: 114148

Strand: Reverse

Name: mcp4 [H]

Synonym: Ddes_0086

Alternate gene names: 220903372

Gene position: 114148-112349 (Counterclockwise)

Preceding gene: 220903373

Following gene: 220903368

Centisome position: 3.97

GC content: 60.22

Gene sequence:

>1800_bases
ATGCTCAGAAATATCAGTATCGCCCAAAGGATCACCTGCTTTGTCACCCTGATGATCGCCATGGTCATCGCCATGGCAGT
CCTGTCCTTTTTTATGACCAGCAACGTCATTGATGAAGGAACCTCGGTTGCCAGAAACCAGTTGCTGGATTCACAGCGCG
CCCGCATCAAGGACGTTACCCAGGCATCGGCCCTCGGCCTGGCTGCCATGACCAGAGGGCTGCCCCCACAGGAGCAGCTG
GGCGTTATTGCCGACTACATAGAAAAATCCCGCTTTGAGGACGATGCTTCGGGCTATTTTTATGTCTATGAAGGCACCGT
CAACGTAGCCCACCCCACACAAAAACAGCTTGTCGGCAAGGATCTGTCCGGCACCGCCGACAAACAGGGCGTACACTACG
TGGTGGAGCTGCACAAAGCTGCGGCAAAGGGCGGTGGATTTGTGGACTTTGTCTTTCCCAAACCCGGCGCCGGTGACGTT
TTCAAACTTGGCTATGCGGAAAAAATAGAAGGCACGCCCTACTGGATCGGCACGGGGGTGTACATTGACAATGTAGACAG
GGAAGAAAACAGGCTGCACAGCACCATGGGCAGCCTGCTTACCCGAACCCTCGGCACGTATGGCGGCGGTTTTCTTGCGG
CGCTGCTGCTCATTGTCGTGCCGCTTTCCTATCGCCTGGCCACCTCCATCACCCGCCCCCTGGCCGGAATCACCGGACAG
GCTCGCGCCGTGGCCGCAGGCAATCTTGATGTAACCATCACGCCTGACGGCAAAGACGAAGTGGCCCTGCTGGAACGGGC
CTTGCGCGACATGGTGGACAAACTGAAAAAGCTCATCAATGAAACGGCAGAAAAAAGCCGCCAGGCCGACGAGGCCGCCA
ATGAGGCCAGAGTCGCCCAAAGCCGGGCCGAACTGGCCGGGCAGGACGCGCAGGCCAAAGCTGCCGCCATGCTTGTGGCT
GCCGACAGGCTTGAGCAGGTGGCCCATGCGGTCAGCACCGCCTCGACCCAGCTTTCCACCCAGATCGAGCAGTCCGACAG
GGGCGCGATGGATTCGGCCCAGCGCCTCACCGAGGCCGCGGCAGCCATCAACCAGATGAACGCCACGGTGCAGAGTGTGG
CCCAAAACGCAACCCAGGCCTCCGCAAGCTCCCACGACACGCGCGAAAAGGCCGTAGCCGGGGCGCACATTGTCGAGCAG
GCCGTACGCAGCATCAGCCAGGTGCACGAAGTTTCGCAGCGCCTGACGGAAAATATGGGGCAGCTCAATGATCAGGCCCA
GGCCATCAGCAAGATCATGAACGTCATCTCCGACATCGCGGACCAGACCAACCTGCTGGCCCTTAATGCCGCCATTGAGG
CGGCCCGCGCAGGAGACGCAGGGCGCGGCTTTGCCGTGGTGGCCGACGAGGTGCGCAAACTGGCCGAAAAAACCATGGCC
TCCACCCACGATGTGGGCGCAGCCATCACCTCCATCCAGGCGAGCACGGCCAAAAGCATGACCGCGATGGAAACTGCCAC
AGAACAGGTGAGCCAGGCCACGGAATTCGCCCATCAGTCCGGTCAGGCTCTGGAAGAAATCGTCAGTACGGTGGAAGCCA
CGGCCGACCAGGTCAACGCCATTGCGGCGGCCAGCGAGCAGCAGTCCGTTGCCAGCGAAGAGATCAACCGCTCCATCAGC
ACAGTAAACGATGTGGTGCAGCAAACCGCTGAAGCCATGCACGAGGCGGCCCTTGCCGTCAGTGACCTGGCCCGGCAGGC
ACAGAACCTGAGCAGCCTCATCGGTGACATGAAAAAATAA

Upstream 100 bases:

>100_bases
CACATACCAAACGGCCACGGCCAATGCCCCCAAACACCCCAAACCAGCCCAGTATCGCCGCCCGGCGGGCGCAGCCGCCC
GCCCAAGGCCGGAGAATCTC

Downstream 100 bases:

>100_bases
CCGCGCCCGACGCAAAAATCCCGCCAGCTGCAATCCGCAGCCGGCGGGATTTTTTCATTTCTGTGTCAGTGCGTGTTGCC
CGTACCCGATCCGCGCATGC

Product: Cache sensor-containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MLRNISIAQRITCFVTLMIAMVIAMAVLSFFMTSNVIDEGTSVARNQLLDSQRARIKDVTQASALGLAAMTRGLPPQEQL
GVIADYIEKSRFEDDASGYFYVYEGTVNVAHPTQKQLVGKDLSGTADKQGVHYVVELHKAAAKGGGFVDFVFPKPGAGDV
FKLGYAEKIEGTPYWIGTGVYIDNVDREENRLHSTMGSLLTRTLGTYGGGFLAALLLIVVPLSYRLATSITRPLAGITGQ
ARAVAAGNLDVTITPDGKDEVALLERALRDMVDKLKKLINETAEKSRQADEAANEARVAQSRAELAGQDAQAKAAAMLVA
ADRLEQVAHAVSTASTQLSTQIEQSDRGAMDSAQRLTEAAAAINQMNATVQSVAQNATQASASSHDTREKAVAGAHIVEQ
AVRSISQVHEVSQRLTENMGQLNDQAQAISKIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMA
STHDVGAAITSIQASTAKSMTAMETATEQVSQATEFAHQSGQALEEIVSTVEATADQVNAIAAASEQQSVASEEINRSIS
TVNDVVQQTAEAMHEAALAVSDLARQAQNLSSLIGDMKK

Sequences:

>Translated_599_residues
MLRNISIAQRITCFVTLMIAMVIAMAVLSFFMTSNVIDEGTSVARNQLLDSQRARIKDVTQASALGLAAMTRGLPPQEQL
GVIADYIEKSRFEDDASGYFYVYEGTVNVAHPTQKQLVGKDLSGTADKQGVHYVVELHKAAAKGGGFVDFVFPKPGAGDV
FKLGYAEKIEGTPYWIGTGVYIDNVDREENRLHSTMGSLLTRTLGTYGGGFLAALLLIVVPLSYRLATSITRPLAGITGQ
ARAVAAGNLDVTITPDGKDEVALLERALRDMVDKLKKLINETAEKSRQADEAANEARVAQSRAELAGQDAQAKAAAMLVA
ADRLEQVAHAVSTASTQLSTQIEQSDRGAMDSAQRLTEAAAAINQMNATVQSVAQNATQASASSHDTREKAVAGAHIVEQ
AVRSISQVHEVSQRLTENMGQLNDQAQAISKIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMA
STHDVGAAITSIQASTAKSMTAMETATEQVSQATEFAHQSGQALEEIVSTVEATADQVNAIAAASEQQSVASEEINRSIS
TVNDVVQQTAEAMHEAALAVSDLARQAQNLSSLIGDMKK
>Mature_599_residues
MLRNISIAQRITCFVTLMIAMVIAMAVLSFFMTSNVIDEGTSVARNQLLDSQRARIKDVTQASALGLAAMTRGLPPQEQL
GVIADYIEKSRFEDDASGYFYVYEGTVNVAHPTQKQLVGKDLSGTADKQGVHYVVELHKAAAKGGGFVDFVFPKPGAGDV
FKLGYAEKIEGTPYWIGTGVYIDNVDREENRLHSTMGSLLTRTLGTYGGGFLAALLLIVVPLSYRLATSITRPLAGITGQ
ARAVAAGNLDVTITPDGKDEVALLERALRDMVDKLKKLINETAEKSRQADEAANEARVAQSRAELAGQDAQAKAAAMLVA
ADRLEQVAHAVSTASTQLSTQIEQSDRGAMDSAQRLTEAAAAINQMNATVQSVAQNATQASASSHDTREKAVAGAHIVEQ
AVRSISQVHEVSQRLTENMGQLNDQAQAISKIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMA
STHDVGAAITSIQASTAKSMTAMETATEQVSQATEFAHQSGQALEEIVSTVEATADQVNAIAAASEQQSVASEEINRSIS
TVNDVVQQTAEAMHEAALAVSDLARQAQNLSSLIGDMKK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=347, Percent_Identity=30.2593659942363, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788194, Length=387, Percent_Identity=29.4573643410853, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI2367378, Length=359, Percent_Identity=27.8551532033426, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787690, Length=392, Percent_Identity=27.8061224489796, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1789453, Length=423, Percent_Identity=25.2955082742317, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63531; Mature: 63531

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNISIAQRITCFVTLMIAMVIAMAVLSFFMTSNVIDEGTSVARNQLLDSQRARIKDVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASALGLAAMTRGLPPQEQLGVIADYIEKSRFEDDASGYFYVYEGTVNVAHPTQKQLVGK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECEEECCCCHHHHHHCC
DLSGTADKQGVHYVVELHKAAAKGGGFVDFVFPKPGAGDVFKLGYAEKIEGTPYWIGTGV
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCHHHCCCCCEEEECCE
YIDNVDREENRLHSTMGSLLTRTLGTYGGGFLAALLLIVVPLSYRLATSITRPLAGITGQ
EEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ARAVAAGNLDVTITPDGKDEVALLERALRDMVDKLKKLINETAEKSRQADEAANEARVAQ
CCEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAELAGQDAQAKAAAMLVAADRLEQVAHAVSTASTQLSTQIEQSDRGAMDSAQRLTEAA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AAINQMNATVQSVAQNATQASASSHDTREKAVAGAHIVEQAVRSISQVHEVSQRLTENMG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNDQAQAISKIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMA
HCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
STHDVGAAITSIQASTAKSMTAMETATEQVSQATEFAHQSGQALEEIVSTVEATADQVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IAAASEQQSVASEEINRSISTVNDVVQQTAEAMHEAALAVSDLARQAQNLSSLIGDMKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRNISIAQRITCFVTLMIAMVIAMAVLSFFMTSNVIDEGTSVARNQLLDSQRARIKDVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QASALGLAAMTRGLPPQEQLGVIADYIEKSRFEDDASGYFYVYEGTVNVAHPTQKQLVGK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECEEECCCCHHHHHHCC
DLSGTADKQGVHYVVELHKAAAKGGGFVDFVFPKPGAGDVFKLGYAEKIEGTPYWIGTGV
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCHHHCCCCCEEEECCE
YIDNVDREENRLHSTMGSLLTRTLGTYGGGFLAALLLIVVPLSYRLATSITRPLAGITGQ
EEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ARAVAAGNLDVTITPDGKDEVALLERALRDMVDKLKKLINETAEKSRQADEAANEARVAQ
CCEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAELAGQDAQAKAAAMLVAADRLEQVAHAVSTASTQLSTQIEQSDRGAMDSAQRLTEAA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AAINQMNATVQSVAQNATQASASSHDTREKAVAGAHIVEQAVRSISQVHEVSQRLTENMG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNDQAQAISKIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMA
HCCHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
STHDVGAAITSIQASTAKSMTAMETATEQVSQATEFAHQSGQALEEIVSTVEATADQVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IAAASEQQSVASEEINRSISTVNDVVQQTAEAMHEAALAVSDLARQAQNLSSLIGDMKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]