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The map label for this gene is hutU [H]

Identifier: 21911309

GI number: 21911309

Start: 1795569

End: 1797599

Strand: Direct

Name: hutU [H]

Synonym: SpyM3_1773

Alternate gene names: 21911309

Gene position: 1795569-1797599 (Clockwise)

Preceding gene: 21911307

Following gene: 21911310

Centisome position: 94.48

GC content: 44.81

Gene sequence:

>2031_bases
ATGTCATTTTACAGTGAAACTGACATAGCTGCCGCTATGACTGTTAAGTTAGACGATGTTTTACCGGAAAAGACTGTCTT
CAAAGAAGGTATCCGAAGAGCACCGGACAGAGGTTTTCGATTGACCCAGTCTCAAACCGAAATTGCCTTAAAAAATGCCC
TACGCTATGTACCTACAAAGTTCCACGAAGAAGTCATTCCAGAATTTTTGGAAGAACTCAAAACAAGGGGACGCATCTAT
GGTTACAGATGGCGTCCAAAAGACCGCATTTACGGCAAACCCATTGACGAGTACAAGGGAAATTGTACAGCTGCCAAGGC
CATGCAGGTCATGATTGACAATAACTTGAGTTTTGAGATTGCCTTGTACCCTTACGAACTAGTCACTTATGGAGAAACTG
GTTCTGTTTGTGCTAACTGGATGCAATACCAATTTATCAAAAAATACCTAGAAGTCATGACTGATGAACAAACCTTGGTG
GTTGAGTCTGGTCATCCAGTTGGTCTTTTCAAATCCAAACCTGAAGCGCCTCGCGTTATCATTACAAATGGCCTTTTGGT
GGGTGAATACGACAACATGAAAGACTGGGAAATCGCTGAAGAGATGGGTGTCACCAACTATGGTCAAATGACCGCAGGTG
GTTGGATGTATATTGGCCCACAAGGAATCGTTCATGGAACGTTTAATACCCTCTTAAATGCTGGTCGTCTCAAACTTGGA
GTGGCTGATGATGGTGATTTGACCGGTAAACTCTTTATCTCATCTGGTTTAGGAGGCATGAGCGGGGCACAAGGTAAGGC
TGCTGAAATTGCTAAAGCCGTTGCCATTATTGCTGAAGTTGACCAATCTCGGATTGAAACCCGTCATTCGCAAGGCTGGG
TTAGCCAAATTGCTGAGAGCCCTGAAGAAGCTCTGCAATTAGCCCAAAAAGCCATAGATGCTAAGGAGTCCACTTCGATT
GCTTACCATGGTAATATCGTTGACCTTTTAGAATACGTCAATGACAAGCAGATTCATGTTGATCTTTTGTCTGACCAAAC
CTCTTGTCACAACGTTTATGACGGTGGCTACTGTCCAGTCGGCATCACTTTTGACGAAAGAACCCGGCTCTTGGCAGAAG
ATAAAGATACCTTCCACCAAATGGTTGATGATACCTTGGCACGGCATTTTGAAGCTATTAAGACGTTAACTGAAAATGGC
ACCTATTTCTTTGACTACGGCAATGCCTTTATGAAGTCTGTTTACGACTCTGGTATTACAGAAATTTCTAAGAATGGTCG
TAACGACAAAGACGGCTTTATCTGGCCATCCTATGTGGAAGATATCATGGGACCTATGCTTTTTGACTATGGCTATGGAC
CTTTCCGTTGGGTCTGCTTGAGTGGTAAACACGAAGACTTGGTGGCTACTGACAAAGCTGCCATGGAAGCTATCGATCCT
GACCGCCGCTATCAAGACCGTGATAACTACAACTGGATTCGTGATGCTGAGAAAAATCAACTCGTAGTTGGTACCCAAGC
CCGGATCCTTTACCAAGACTGTATCGGTCGTGTGACTGTCGCCCTTAAATTTAATGAATTGGTCCGCAAAGGCAAGATTG
GACCTGTCATGATTGGTCGTGACCACCATGACGTGTCTGGTACCGACTCACCATTTCGTGAAACCTCAAACATTAAAGAC
GGTTCCAATGTGACCTGTGATATGGCGGTGCAATGTTACGCTGGTAACGCTGCGCGTGGTATGAGTTTAGTGGCTCTTCA
CAACGGTGGCGGAACTGGTATTGGTAAAGCCATCAATGGTGGTTTCGGACTTGTTTTAGATGGCAGCGAACGCATTGATG
AGATTATTAAATCTGCTATTGCTTGGGATACTATGGGCGGTGTAGCTCGCCGTAACTGGGCCCGCAATGAGCACGCTATT
GAAACCGCTATTGAATACAACCGTCTCCATGCAGGTACTGATCACATCACTATCCCATACTTGGCTGATGATGACCTTGT
GACTTCAGCGGTAGATCAATTATTTCACTAA

Upstream 100 bases:

>100_bases
TTTAGACTTTTTTCGCATTTCAAAGCGTGGTTGACTTTTTATAGACTAGACTAAGTTAGACTAATCTCGACAATAAAAAG
GAGTTGAGGAGGAGTTTTCT

Downstream 100 bases:

>100_bases
TAACTGCTAGCTAAAAATGTAAGCGTTATCTAAAGTAGGTAACCTATTCCCCTAATGAGTAACTCAATGACATAAAAGGA
GATTAACATGGCGAAAATTG

Product: urocanate hydratase

Products: NA

Alternate protein names: Urocanase; Imidazolonepropionate hydrolase [H]

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQSQTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIY
GYRWRPKDRIYGKPIDEYKGNCTAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYQFIKKYLEVMTDEQTLV
VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLG
VADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAIIAEVDQSRIETRHSQGWVSQIAESPEEALQLAQKAIDAKESTSI
AYHGNIVDLLEYVNDKQIHVDLLSDQTSCHNVYDGGYCPVGITFDERTRLLAEDKDTFHQMVDDTLARHFEAIKTLTENG
TYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDYGYGPFRWVCLSGKHEDLVATDKAAMEAIDP
DRRYQDRDNYNWIRDAEKNQLVVGTQARILYQDCIGRVTVALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKD
GSNVTCDMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDTMGGVARRNWARNEHAI
ETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH

Sequences:

>Translated_676_residues
MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQSQTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIY
GYRWRPKDRIYGKPIDEYKGNCTAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYQFIKKYLEVMTDEQTLV
VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLG
VADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAIIAEVDQSRIETRHSQGWVSQIAESPEEALQLAQKAIDAKESTSI
AYHGNIVDLLEYVNDKQIHVDLLSDQTSCHNVYDGGYCPVGITFDERTRLLAEDKDTFHQMVDDTLARHFEAIKTLTENG
TYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDYGYGPFRWVCLSGKHEDLVATDKAAMEAIDP
DRRYQDRDNYNWIRDAEKNQLVVGTQARILYQDCIGRVTVALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKD
GSNVTCDMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDTMGGVARRNWARNEHAI
ETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH
>Mature_675_residues
SFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQSQTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYG
YRWRPKDRIYGKPIDEYKGNCTAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYQFIKKYLEVMTDEQTLVV
ESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLGV
ADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAIIAEVDQSRIETRHSQGWVSQIAESPEEALQLAQKAIDAKESTSIA
YHGNIVDLLEYVNDKQIHVDLLSDQTSCHNVYDGGYCPVGITFDERTRLLAEDKDTFHQMVDDTLARHFEAIKTLTENGT
YFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDYGYGPFRWVCLSGKHEDLVATDKAAMEAIDPD
RRYQDRDNYNWIRDAEKNQLVVGTQARILYQDCIGRVTVALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDG
SNVTCDMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDTMGGVARRNWARNEHAIE
TAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH

Specific function: Unknown

COG id: COG2987

COG function: function code E; Urocanate hydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urocanase family [H]

Homologues:

Organism=Homo sapiens, GI21389467, Length=668, Percent_Identity=45.8083832335329, Blast_Score=582, Evalue=1e-166,
Organism=Homo sapiens, GI260306182, Length=728, Percent_Identity=41.6208791208791, Blast_Score=527, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI71997891, Length=649, Percent_Identity=46.6872110939908, Blast_Score=591, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000193 [H]

Pfam domain/function: PF01175 Urocanase [H]

EC number: =4.2.1.49 [H]

Molecular weight: Translated: 75320; Mature: 75189

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00024 HEMOPEXIN ; PS01233 UROCANASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQSQTEIALKNALRYVPTK
CCCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCHH
FHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPIDEYKGNCTAAKAMQVMIDNNLSFEI
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHCCCCCHHHHEEEEECCCCEEEE
ALYPYELVTYGETGSVCANWMQYQFIKKYLEVMTDEQTLVVESGHPVGLFKSKPEAPRVI
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCEEE
ITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLG
EECCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHCCCCEEEE
VADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAIIAEVDQSRIETRHSQGWVSQIAES
ECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVNDKQIHVDLLSDQTSCHNVYDGGYCPV
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEE
GITFDERTRLLAEDKDTFHQMVDDTLARHFEAIKTLTENGTYFFDYGNAFMKSVYDSGIT
EEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHH
EISKNGRNDKDGFIWPSYVEDIMGPMLFDYGYGPFRWVCLSGKHEDLVATDKAAMEAIDP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCHHHHHHCCC
DRRYQDRDNYNWIRDAEKNQLVVGTQARILYQDCIGRVTVALKFNELVRKGKIGPVMIGR
CCCCCCCCCCCHHCCCCCCEEEEECHHHHHHHHHHHHEEEEEEHHHHHHCCCCCCEEECC
DHHDVSGTDSPFRETSNIKDGSNVTCDMAVQCYAGNAARGMSLVALHNGGGTGIGKAING
CCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCHHCCC
GFGLVLDGSERIDEIIKSAIAWDTMGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPY
CEEEEECCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHEECCCCCEEEEE
LADDDLVTSAVDQLFH
ECCCHHHHHHHHHHCC
>Mature Secondary Structure 
SFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQSQTEIALKNALRYVPTK
CCCCCCCCEEEEEEEHHHCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHCCHH
FHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPIDEYKGNCTAAKAMQVMIDNNLSFEI
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHCCCCCHHHHEEEEECCCCEEEE
ALYPYELVTYGETGSVCANWMQYQFIKKYLEVMTDEQTLVVESGHPVGLFKSKPEAPRVI
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCEEE
ITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYIGPQGIVHGTFNTLLNAGRLKLG
EECCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHHHHCCCCEEEE
VADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAIIAEVDQSRIETRHSQGWVSQIAES
ECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVNDKQIHVDLLSDQTSCHNVYDGGYCPV
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEE
GITFDERTRLLAEDKDTFHQMVDDTLARHFEAIKTLTENGTYFFDYGNAFMKSVYDSGIT
EEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHH
EISKNGRNDKDGFIWPSYVEDIMGPMLFDYGYGPFRWVCLSGKHEDLVATDKAAMEAIDP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCHHHHHHCCC
DRRYQDRDNYNWIRDAEKNQLVVGTQARILYQDCIGRVTVALKFNELVRKGKIGPVMIGR
CCCCCCCCCCCHHCCCCCCEEEEECHHHHHHHHHHHHEEEEEEHHHHHHCCCCCCEEECC
DHHDVSGTDSPFRETSNIKDGSNVTCDMAVQCYAGNAARGMSLVALHNGGGTGIGKAING
CCCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCHHCCC
GFGLVLDGSERIDEIIKSAIAWDTMGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPY
CEEEEECCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHEECCCCCEEEEE
LADDDLVTSAVDQLFH
ECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA