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The map label for this gene is scrR [H]

Identifier: 21911107

GI number: 21911107

Start: 1573136

End: 1573981

Strand: Direct

Name: scrR [H]

Synonym: SpyM3_1571

Alternate gene names: 21911107

Gene position: 1573136-1573981 (Clockwise)

Preceding gene: 21911106

Following gene: 21911114

Centisome position: 82.77

GC content: 37.59

Gene sequence:

>846_bases
ATGCGTGAATTGGGCTACAAGCCTAACAATCTCGCTAGAAGTTTGCAAGGTAAATCAACCCAACTCATTGGGCTTATCTT
CCCCAACATTAGCAATATCTTTTACGCTGAATTAATTGAACATCTGGAAATTGAATTGTTTAAACAGGGCTACAAAACTA
TTATTTGCAATAGTGAACATAATCCCGTCAAAGAACGTGAATACTTAGAAATGCTTGCGGCCAATCAAGTGGACGGCATT
ATTTCTTCCAGCCATAATTTGGGAATTGAAGATTATGAGCGTGTCGAAGCTCCTATTGTAGCTTTTGACCGTAATCTGGC
GCCAAATATCCCGGTTATTTCTTCAGATAATTTTGAAGGTGGTAAATTAGCCGCACAAACTTTGCAAAAACACGGTTGTC
AAAACATTGTCATGATTACAGGTAATGACAATTCTGATTCGCCCACAGGGTTGCGCCAGCTAGGGTTTAACTACCAGCTC
AAACGAAGTGCAGAAATCATCAAATTACCAAATAACCTATCTCCTGTTAGACGCGAAATGGAAATTAAATCCATTTTGGC
AACCCGAAAACCTGATGGCCTTTTCGTTTCTGATGATTTAACTGCTATCCTCATTATGAAAGTAGCCAAACAACTTCACA
TTACTATTCCAGAGGATATGAAAGTCATAGGTTATGATGGAACGACATTTATCCAGCAATATGTTCCTCAATTAGCGACC
ATTCGTCAACCTATTGATGAGATTGCTAAATTGAGTGTCGAAATACTCATTAAAAAAATTAAAAAAGAAAAAACCAGTAA
AGACTATATTTTACCGATTACGCTACTTCCAGGAGCAAGTATTTAA

Upstream 100 bases:

>100_bases
CGTGGCAGCCTTGGCGGGTGTCAGTCCAACAACTGTTTCGCGAGTAATCAACAAAAAAGGCTACCTTTCCCAAAAAACAG
TGAATAAGGTGAATAAGGCC

Downstream 100 bases:

>100_bases
ACAAAGCATAACCAATCACTAATTACTCTAAAAGACAAACAAGCATACTCTTTCTAGATGCGAGAGTATGCTTGTTTGTC
TTTTAATATTCGTACATAAA

Product: putative sucrose operon repressor

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGI
ISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEGGKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQL
KRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLAT
IRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI

Sequences:

>Translated_281_residues
MRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGI
ISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEGGKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQL
KRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLAT
IRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI
>Mature_281_residues
MRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGI
ISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEGGKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQL
KRSAEIIKLPNNLSPVRREMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLAT
IRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=277, Percent_Identity=30.6859205776173, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787948, Length=273, Percent_Identity=27.4725274725275, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI48994940, Length=296, Percent_Identity=25.3378378378378, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790369, Length=272, Percent_Identity=24.2647058823529, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789068, Length=259, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788474, Length=266, Percent_Identity=23.3082706766917, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790715, Length=278, Percent_Identity=21.9424460431655, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786540, Length=293, Percent_Identity=24.2320819112628, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786268, Length=280, Percent_Identity=26.0714285714286, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789202, Length=259, Percent_Identity=25.4826254826255, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 31499; Mature: 31499

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50932 HTH_LACI_2 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEH
CCCCCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
NPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEEECCCCCCCCCEEECCCCCC
GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREM
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCEEECCCCEEEECCCCCHHHHHHH
EIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLAT
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHH
IRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MRELGYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEH
CCCCCCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
NPVKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCEEEECCCCCCCCCEEECCCCCC
GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRREM
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHCCCEEECCCCEEEECCCCCHHHHHHH
EIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLAT
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHH
IRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9673256; 12397186 [H]