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The map label for this gene is speK [H]

Identifier: 21910741

GI number: 21910741

Start: 1231883

End: 1232662

Strand: Reverse

Name: speK [H]

Synonym: SpyM3_1205

Alternate gene names: 21910741

Gene position: 1232662-1231883 (Counterclockwise)

Preceding gene: 21910742

Following gene: 21910740

Centisome position: 64.86

GC content: 28.85

Gene sequence:

>780_bases
ATGAAAAAAAATACCTTGACTTTGTTATTCCTTGTGTGTGTATCGCTTGCTCTATACACTACTGAGAGTGTCTTTTCAGA
TACGTACAATACAAATGATGTTAGAAATCCAAGGAACATATATGCTCCTAGATATGATAAAGACGAAATTTTGGATAATA
GAAGATTAAAAGAAATATATAATAAAGAAATTATTGAAAAAAATAATATATCGATAAATGCCAAACAAGGAACGCAATTG
ATTTTTAATACGGATGAAAATACTACAGTTTGGAATGATAACACTTTTAAGAAAGTCATATCTAGTAATCTTTCTCCTTC
ACAGGAAAGAATGTTTAATGTTGGTGATCATGTGAATATTTTTGCTATAGTAAAGTCATATCATGTTGTATGCAAGGAAC
AATTCAATTATAGTGATGGGGGAATAATAAAAACAAGTGATGTAAAACCAGAAGAAAAAGCAATTTATATTAATATTTTT
GGTGAAAAAGAATTACGAACATTAACAGCTAAAGATAAGATTACCTTTAAAAATAATATTGTAACTCTTCAGGAGATTGA
TGTTAGACTTAGGAAAAGTTTGATGGGGGACAGCAAAATAAAATTGTATGAGTACGATTCTTTGTATAAAAAAGGGTTTT
GGGATATTCATTATAAAGACGGTGGCATTAGACACACCAATTTATTTACTTACCCCGACTATACAGATAATGAAACGATT
GATATGAGTAAAGTTAGTCACTTTGATGTTCACTTAAACGAAGATTTTTCTAAAGATTAG

Upstream 100 bases:

>100_bases
GTTTTTTTTGTGTTTTTTTAAAATTATAGTTGAATTATTATTTAAATATAGTATACTTGCTAAACAAATTGATTAAACTT
AAAAAATGTTAGGAGAAAAA

Downstream 100 bases:

>100_bases
TGGTTGAATGCTATTTTAATTTAATTTTTAGTCTATTTAAATAGATTTTGATGAATTAGACGGTTTTAGTAGACTTCTAG
GCATCACTATCGGTCAACCG

Product: streptococcal pyrogenic exotoxin SpeK - phage associated

Products: NA

Alternate protein names: SPE C [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQL
IFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIF
GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
DMSKVSHFDVHLNEDFSKD

Sequences:

>Translated_259_residues
MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQL
IFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIF
GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
DMSKVSHFDVHLNEDFSKD
>Mature_259_residues
MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQL
IFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIF
GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
DMSKVSHFDVHLNEDFSKD

Specific function: Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylococcal/streptococcal toxin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008992
- InterPro:   IPR006126
- InterPro:   IPR006173
- InterPro:   IPR016091
- InterPro:   IPR013307
- InterPro:   IPR006123
- InterPro:   IPR006177 [H]

Pfam domain/function: PF02876 Stap_Strp_tox_C; PF01123 Stap_Strp_toxin [H]

EC number: NA

Molecular weight: Translated: 30280; Mature: 30280

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPRYDKDEILDNRRLKEIY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
NKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNI
HHHHEECCCCEEEECCCCEEEEECCCCCEEECCCHHHHHHHCCCCCCHHHHCCCCCCEEE
FAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIFGEKELRTLTAKDKITFKNNI
EEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEECCCHHEEEECCCCEEECCCE
VTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
EEHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCEEEEECCCCEEECEEEECCCCCCCCEE
DMSKVSHFDVHLNEDFSKD
ECCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPRYDKDEILDNRRLKEIY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
NKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNI
HHHHEECCCCEEEECCCCEEEEECCCCCEEECCCHHHHHHHCCCCCCHHHHCCCCCCEEE
FAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIFGEKELRTLTAKDKITFKNNI
EEEEHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEECCCHHEEEECCCCEEECCCE
VTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
EEHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCEEEEECCCCEEECEEEECCCCCCCCEE
DMSKVSHFDVHLNEDFSKD
ECCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]