Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 21910737

GI number: 21910737

Start: 1227589

End: 1229322

Strand: Reverse

Name: yesM [H]

Synonym: SpyM3_1201

Alternate gene names: 21910737

Gene position: 1229322-1227589 (Counterclockwise)

Preceding gene: 21910738

Following gene: 21910736

Centisome position: 64.68

GC content: 43.37

Gene sequence:

>1734_bases
ATGAAGCGTTATCCCCTACTGGTCCAGTTGATTTCGTATGTTTTTGTGATCGTAATTGCCCTCATTACCACGCTTGGTTT
GCTTTATTACCAGACGAGTTCTCGTAATATCAGGCAACTAATTGAACGTGATACCCGGCAGAGCATTCGGCAAAGTTCCC
AATTTATTGACGCTTACATCAAGCCTCTTAAAGAAACAACTTCGGTGCTGGCGAAAAATTCGGAAATTCAAGACTTTGCT
AGTCAAATTCATCAAGAAAATGACAAGCAGGTTCTTCAGCTCATGAAGATGGTTCTTGCGACCAATTCCGATTTACAAGC
AGCTGTTCTGGTGACTAAGGATGGTCGAACGGTGTCTACCAATTCTCAGTTGACCATGAAAACCTCCAGTGACATGATGG
CAGAACCCTGGTATAAAGCAGCCATAGACTGTCAAGCCATGCCAGTCTTAACCCCAGCTCGGCAATTATCCCTTTCTTCT
AAAAAAGAATGGGTAGTTTCTGTGACCCAAGAGGTAGTGGATGCTGCTGGTCATAATTTAGGCGTGCTAAGACTTGATAT
TGCATACCCGACCATTAAAGCGTCCTTAGATCAGCTTCAGCTAGGCCGCCAAGGCTTTGCCTTTATTGTGAATGATAAAC
ATGAATTTGTTTACCATCCCAAAAAGAGTGTTTACAGTTCTTCTAAGGAGATGGCTGCGATGAAGCCTTATTTAGCGATT
CAGAATGGTTACACTAAGGACAAGACATCTTTTGTGTACCAAAAACTCATTCCTAACAGTCAATGGACTTTAGTGGGAGT
GGCGTCACTGGATCAGTTGCACCGGGTGCAGCGCCAAATTCTTTGGTCCTTTCTTGGGACAGGGCTTCTAGCCTGTCTGA
TTTGTGGCTTTGCAACTGTCTTAGCCTTACGCAGATGGATTCGTCCCATTCAACAATTGCAGCAAGTTATTCTTGCTATT
CAAAAAGGAGATCGTCAGTTACGTGCCCAAGAAACGGGTTCTCCAGAATTGACAGACCTTGCCCAACAGTTTAATGCGCT
CTTAGATCAAATTGATAGCTTGATGGTTGCCGTTGCGGATAAGGAAAAGGCGATTGGGCAGTATAGGTTACAAGCCTTGG
CTAGTCAGATTAACCCGCATTTTCTCTATAACACCTTGGACACTATTATTTGGATGGCAGAATTTAATGACAGCAAGCGC
GTGGTAGAAGTGACCAAGTCTCTAGCTAAGTATTTTCGTTTGGCCCTTAATCAGGGGAACGAATACATTCGTTTGGCAGA
TGAACTGGATCACGTTAGCCAATACCTCTTTATTCAAAAACAGCGCTATGGAGACAAGCTAAGTTATGAAGTGCAAGGCT
TAGATGTCTACGCAGACTTTGTTATTCCTAAGCTTATCTTACAGCCCTTAGTAGAAAATGCTATCTACCATGGCATCAAA
GAAGTCGATCGCAAGGGCATGATCAAGGTTACGGTATCTGATACAGCTCAGCATCTGATGTTGACTGTTTGGGATAATGG
TAAAGGCATTGAAGACTCTTCACTGACCAATAGTCAGAGCTTGTTGGCTAGGGGAGGTGTGGGCCTTAAAAATGTTGACC
AGCGGTTAAAACTTCACTATGGTGAAGGCTACCACATGACCATTCATAGCCAGTCAGACCAGTTCACTGAAATACAATTA
AGCCTTCCTAAAATGCATGAATTAATGGCAGACGACACACAGGAAAACGAGTAA

Upstream 100 bases:

>100_bases
TTGCAGAGCAGGTCGGTTTTGAGGACATGAATTATTTTTCTCAGCGCTTTAAGCAACTGGTAGGCGTTACCCCAAGTCAG
TATAAAAAAGGAGGCCAGGC

Downstream 100 bases:

>100_bases
GGTTAAAGGAAGTGCATGTCAGCCATTTCCCTAAGTTAGGGTATTGGAGATAAGAACCTTAGAAAGGATATCATGAATTT
AGCAACTGACTATTTTAGCC

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFA
SQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDCQAMPVLTPARQLSLSS
KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAI
QNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQILWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAI
QKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKR
VVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK
EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQL
SLPKMHELMADDTQENE

Sequences:

>Translated_577_residues
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFA
SQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDCQAMPVLTPARQLSLSS
KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAI
QNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQILWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAI
QKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKR
VVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK
EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQL
SLPKMHELMADDTQENE
>Mature_577_residues
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFA
SQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDCQAMPVLTPARQLSLSS
KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAI
QNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQILWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAI
QKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKR
VVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK
EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQL
SLPKMHELMADDTQENE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=205, Percent_Identity=33.1707317073171, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788723, Length=235, Percent_Identity=33.1914893617021, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65414; Mature: 65414

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLKETTSVLAKNSEIQDFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVST
HHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEC
NSQLTMKTSSDMMAEPWYKAAIDCQAMPVLTPARQLSLSSKKEWVVSVTQEVVDAAGHNL
CCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCC
GVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAI
EEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCEEECCHHHHHCCCHHHHHHCCHHEE
QNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQILWSFLGTGLLACLICGFATV
CCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
EYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK
CEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHY
HHCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHEEE
GEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
CCCEEEEEECCCCCCEEEEECCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLKETTSVLAKNSEIQDFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVST
HHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEC
NSQLTMKTSSDMMAEPWYKAAIDCQAMPVLTPARQLSLSSKKEWVVSVTQEVVDAAGHNL
CCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCC
GVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAI
EEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCCEEECCHHHHHCCCHHHHHHCCHHEE
QNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQILWSFLGTGLLACLICGFATV
CCCCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
EYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIK
CEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHY
HHCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHEEE
GEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
CCCEEEEEECCCCCCEEEEECCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]