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The map label for this gene is fdhC [H]

Identifier: 21910623

GI number: 21910623

Start: 1130948

End: 1131727

Strand: Reverse

Name: fdhC [H]

Synonym: SpyM3_1087

Alternate gene names: 21910623

Gene position: 1131727-1130948 (Counterclockwise)

Preceding gene: 21910624

Following gene: 21910622

Centisome position: 59.55

GC content: 38.08

Gene sequence:

>780_bases
ATGAAAACACCAGAACAGATTTTAGAAGCAACTATTCATATTGGGGAACATAAGGTTACCAAAACTTTTTTGGCTAAATC
TATCTTAGGCTTTATTGGTGGAGCGATGATTAGCCTTGGTTATTTACTATACGTGAGAATTGCCGCCAGTGGTTTAGAAG
CTTTTGGTGCTTTTTCCAGTATCGTAGGAGCTTGTGCTTTTCCGATTGGTCTAATTATTATTTTAATGGCGGGTGGAGAA
TTAATTACAGGGAACATGATGGCTGTTTCTGCAGCTTTGTTGGCCAAAAAAATTAAGTTTAGCGAGCTTGCCAAGAATTG
GCTTATCATTACCTTGTTTAATGTGATTGGAGCTGTTTTTGTAGCTTTTGTGTTTGGTCATTTTCTAGGCTTAACATCAG
CTGGTATTTTTAAAGAAGAAGTGATTGAGGTGGCCCATGCTAAAATAGCAGCGAGCCCTTTGCAGGCACTAGTATCAGGA
ATTGGTTGTAACTGGTTTGTTGGTTTGGCCTTGTGGCTATGCTATGGGGCAAATGATGCTGCTGGTAAATTCCTTGGTAC
TTGGTTTCCTGTCATGACCTTTGTAGCCCTTGGTTTTCAGCATAGTGTAGCAAATGCTTTTGTCATTCCTGCTGCTATTT
TTGAAGGAGGAGCAACATGGTTGGATTTTGTCACTAATTTTATTTTTGTCTATAGTGGTAATATTATCGGTGGAGCCATT
TTTGTTAGTTTTTTATATTTTAAAGTTTACTATCATCCGCAAAAGAGTAAAACTCAATGA

Upstream 100 bases:

>100_bases
GATAATGACGAGCCCTTTCTTGTTGAAAGGGCTTGCATTTTTTAGGAAAATTGATATACTAAAGTGTGTGTTTGTGAATA
CAGTAACAAAAGGAGATATC

Downstream 100 bases:

>100_bases
GAAAATATTTTTTTAGACTGAGGGCGTCCTATTCTCAGTCTTCTTTTTATAATTTATGGTAAAATAAGAAGCGAAGTTTA
AAAAATTTAGCTAAATAATG

Product: putative formate dehydrogenase

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLYVRIAASGLEAFGAFSSIVGACAFPIGLIIILMAGGE
LITGNMMAVSAALLAKKIKFSELAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGATWLDFVTNFIFVYSGNIIGGAI
FVSFLYFKVYYHPQKSKTQ

Sequences:

>Translated_259_residues
MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLYVRIAASGLEAFGAFSSIVGACAFPIGLIIILMAGGE
LITGNMMAVSAALLAKKIKFSELAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGATWLDFVTNFIFVYSGNIIGGAI
FVSFLYFKVYYHPQKSKTQ
>Mature_259_residues
MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLYVRIAASGLEAFGAFSSIVGACAFPIGLIIILMAGGE
LITGNMMAVSAALLAKKIKFSELAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGATWLDFVTNFIFVYSGNIIGGAI
FVSFLYFKVYYHPQKSKTQ

Specific function: Involved In The Bidirectional Transport Of Formate. [C]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=276, Percent_Identity=30.0724637681159, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788837, Length=268, Percent_Identity=27.6119402985075, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082249, Length=203, Percent_Identity=29.5566502463054, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321779, Length=240, Percent_Identity=29.5833333333333, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 27725; Mature: 27725

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00213 LIPOCALIN ; PS01005 FORMATE_NITRITE_TP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]