BacMap

Definition	Streptococcus pyogenes MGAS315 chromosome, complete genome.
Accession	NC_004070
Length	1,900,521

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The map label for this gene is yqjQ [H]

Identifier: 21910174

GI number: 21910174

Start: 699109

End: 699873

Strand: Direct

Name: yqjQ [H]

Synonym: SpyM3_0638

Alternate gene names: 21910174

Gene position: 699109-699873 (Clockwise)

Preceding gene: 21910173

Following gene: 21910175

Centisome position: 36.79

GC content: 42.09

Gene sequence:

>765_bases
ATGGCACAAAGAATCATTGTTATCACGGGAGCTTCTGGAGGACTGGCTCAGGCAATTGTTAAGCAGTTACCCAAGGAAGA
CAGCTTGATTTTATTAGGACGTAACAAAGAACGCCTAGAACACTGTTATCAGCATATTGACAACAAAGAATGCCTTGAGT
TGGATATTACCAATCCAGTAGCCATTGAGAAAATGGTCGCCCAGATTTACCAGCGCTATGGCCGTATTGATGTCTTGATT
AATAATGCTGGCTACGGAGCTTTCAAAGGCTTTGAAGAGTTTTCTGCCCAAGAAATAGCTGATATGTTTCAGGTTAACAC
CCTAGCGAGCATTCACTTTGCTTGCTTGATTGGTCAGAAAATGGCAGAGCAGGGGCAAGGCCATCTCATTAATATTGTGT
CCATGGCAGGCTTGATTGCGTCAGCCAAATCGAGCATTTATTCAGCCACCAAGTTTGCCCTTATCGGATTTTCCAATGCC
CTTCGCTTAGAATTAGCGGATAAAGGGGTTTACGTGACCACCGTGAATCCAGGTCCCATTGCCACCAAGTTTTTTGACCA
AGCTGACCCGTCTGGACATTATTTGGAAAGTGTTGGTAAATTTACCCTCCAACCAAATCAAGTGGCTAAGCGCTTGATTT
CCATTATCGGGAAAAATAAACGAGAATTGAATATGCCCTTTAGTTTAGCGGTGACCCATCAATTTTACACCCTTTTCCCT
AAATTATCTGATTATCTTGCAAGAAAGGTATTTAATTATAAATGA

Upstream 100 bases:

>100_bases
CTCGCTTTTTAGGGCGTGATTGTCGCCAGATGGAAAAAGATGCCGCCACTATATTTGAAAATGTTAAAATGGTACAAGAT
TTAGAGGAAGTGATTATTTA

Downstream 100 bases:

>100_bases
TTAAATCCAAATATAGCTGGAAAATAAAAGACAAGAAGCCAGATGATGGCTTCTTTAAGCTAGCAAAGACAAAAGGTCTA
ACCCAGACCGCCGCTCAGTT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLI
NNAGYGAFKGFEEFSAQEIADMFQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLISIIGKNKRELNMPFSLAVTHQFYTLFP
KLSDYLARKVFNYK

Sequences:

>Translated_254_residues
MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLI
NNAGYGAFKGFEEFSAQEIADMFQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLISIIGKNKRELNMPFSLAVTHQFYTLFP
KLSDYLARKVFNYK
>Mature_253_residues
AQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLIN
NAGYGAFKGFEEFSAQEIADMFQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNAL
RLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLISIIGKNKRELNMPFSLAVTHQFYTLFPK
LSDYLARKVFNYK

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=209, Percent_Identity=29.6650717703349, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4503817, Length=221, Percent_Identity=26.6968325791855, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7657478, Length=270, Percent_Identity=26.2962962962963, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20149619, Length=257, Percent_Identity=25.6809338521401, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=27.5, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=28.1512605042017, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI59889578, Length=134, Percent_Identity=32.089552238806, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI142976729, Length=246, Percent_Identity=27.2357723577236, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157739938, Length=259, Percent_Identity=23.1660231660232, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI226371731, Length=227, Percent_Identity=27.3127753303965, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI40807363, Length=238, Percent_Identity=27.3109243697479, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI210032110, Length=257, Percent_Identity=24.124513618677, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI31542939, Length=236, Percent_Identity=25.8474576271186, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705855, Length=196, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40254992, Length=181, Percent_Identity=24.3093922651934, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7705925, Length=194, Percent_Identity=24.7422680412371, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=31.5217391304348, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=29.0322580645161, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786701, Length=238, Percent_Identity=26.0504201680672, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=186, Percent_Identity=30.6451612903226, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788459, Length=161, Percent_Identity=33.5403726708075, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790717, Length=189, Percent_Identity=28.042328042328, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787526, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367365, Length=218, Percent_Identity=25.6880733944954, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.3505154639175, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=194, Percent_Identity=29.3814432989691, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=188, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=218, Percent_Identity=25.6880733944954, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=212, Percent_Identity=29.7169811320755, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=213, Percent_Identity=27.2300469483568, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=245, Percent_Identity=24.0816326530612, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=198, Percent_Identity=26.7676767676768, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=227, Percent_Identity=28.6343612334802, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=228, Percent_Identity=25.4385964912281, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557668, Length=248, Percent_Identity=27.0161290322581, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=191, Percent_Identity=28.2722513089005, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559552, Length=192, Percent_Identity=28.125, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=210, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=256, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=255, Percent_Identity=22.7450980392157, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=219, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=196, Percent_Identity=25.5102040816327, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=192, Percent_Identity=26.0416666666667, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=30.2564102564103, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323458, Length=238, Percent_Identity=28.1512605042017, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=242, Percent_Identity=24.3801652892562, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=28.8659793814433, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI28571526, Length=205, Percent_Identity=30.7317073170732, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=30.4812834224599, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358495, Length=233, Percent_Identity=26.1802575107296, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221510726, Length=192, Percent_Identity=33.8541666666667, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=30.3030303030303, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=28.7234042553192, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24580925, Length=201, Percent_Identity=27.8606965174129, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571387, Length=225, Percent_Identity=28, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=189, Percent_Identity=29.1005291005291, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355631, Length=269, Percent_Identity=23.7918215613383, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24581726, Length=197, Percent_Identity=25.8883248730964, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364892, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=186, Percent_Identity=27.4193548387097, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356301, Length=223, Percent_Identity=26.9058295964126, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649181, Length=264, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=190, Percent_Identity=25.2631578947368, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28180; Mature: 28049

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKECLELDITNPV
CCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCH
AIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADMFQVNTLASIHFACLIGQK
HHHHHHHHHHHHCCCEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNALRLELADKGVYVTTVNPGPI
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECCCEEEEEECCCCC
ATKFFDQADPSGHYLESVGKFTLQPNQVAKRLISIIGKNKRELNMPFSLAVTHQFYTLFP
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHH
KLSDYLARKVFNYK
HHHHHHHHHHHCCC
>Mature Secondary Structure 
AQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQHIDNKECLELDITNPV
CCEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCH
AIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADMFQVNTLASIHFACLIGQK
HHHHHHHHHHHHCCCEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNALRLELADKGVYVTTVNPGPI
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEECCCEEEEEECCCCC
ATKFFDQADPSGHYLESVGKFTLQPNQVAKRLISIIGKNKRELNMPFSLAVTHQFYTLFP
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHH
KLSDYLARKVFNYK
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]