Click here to switch to the map view.

The map label for this gene is fruK [H]

Identifier: 21910115

GI number: 21910115

Start: 636776

End: 637564

Strand: Direct

Name: fruK [H]

Synonym: SpyM3_0579

Alternate gene names: 21910115

Gene position: 636776-637564 (Clockwise)

Preceding gene: 21910114

Following gene: 21910116

Centisome position: 33.51

GC content: 40.81

Gene sequence:

>789_bases
GTGAGTCGCATCTTGCAACGTTTAGACATTGCTAGCACGGCGACAGGGTTCTTGGGTGGTTTTACAGGACGTTTTATCGA
AGAAAGTTTGAGTGCAGAAGGCGTTAAAACTGATTTTGTAAAAGGTGATCAAGATACTCGAATCAATGTTAAAATCAAGT
CACAAGAAGAGACCGAATTAAATGGTCAAGGACCTATCATTAGTCGGGAACAACTAGAGGAGTTGAAAACTAAGCTTTCC
CAGCTAACAGCAGAGGATACAGTTGTCTTTGCAGGTTCAGCGCCAGCTAATCTTGGCAATGCTGTTTATAAGGAATTACT
TCCTTTAGTTAGGCAAAGCGGTGCTCAGGTGGTTTGTGATTTTGAAGGACAGACTTTAATAGATGCGCTTGCATATAATC
CTCTGTTGGTTAAACCTAATAATCATGAACTAGAAGCTATTTTTGGTACGATTCTGACTAGTCTTGATGATGTTGAAACC
TATGCCCGTCGTCTTTTAGAGATGGGTGCTCAAAATGTCATCATTTCAATGGCTGGTGATGGTGCTTTGCTGGTTACTAA
AGAAGCGACTTATTTTGCTAAACCGATTAAGGGAGAAGTTAAAAATTCTGTCGGTGCTGGTGATTCGATGGTTGCTGGCT
TTACAGGCGAATTTATGAAGAGTCAAAATCCAATAGAAGCCTTAAAATGGGGCGTGGCTTGTGGTACAGCGACGGCTTTC
TCTGATGACTTGGCGACAATTGCATTTATTAAGGAAACATATCATAAAGTTGAGGTAGAAAAACGATGA

Upstream 100 bases:

>100_bases
CCCTTCTATTGACTTTATTGTCAGAATTGACCAAATAAATCTTGGGTCAGTGAATCGCATGGCGAGTGATGATAAGTTTG
CTGGAGGTAAAGGCATTAAT

Downstream 100 bases:

>100_bases
AAATTCAAGATTTATTGAGAAAAGATATTATGATTCTCGATTTACAGGCTATTTCTAAAGAAGTTGCCATTGACGAGATG
ATTACTAAATTAGTTGAAAA

Product: putative fructose-1-phosphate kinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELNGQGPIISREQLEELKTKLS
QLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCDFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVET
YARRLLEMGAQNVIISMAGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAF
SDDLATIAFIKETYHKVEVEKR

Sequences:

>Translated_262_residues
MSRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELNGQGPIISREQLEELKTKLS
QLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCDFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVET
YARRLLEMGAQNVIISMAGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAF
SDDLATIAFIKETYHKVEVEKR
>Mature_261_residues
SRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELNGQGPIISREQLEELKTKLSQ
LTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCDFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETY
ARRLLEMGAQNVIISMAGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAFS
DDLATIAFIKETYHKVEVEKR

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=217, Percent_Identity=33.6405529953917, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788017, Length=246, Percent_Identity=28.8617886178862, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 28329; Mature: 28197

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCCCCC
NGQGPIISREQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCD
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEE
FEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISMAGD
CCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAF
CEEEEEECCHHHHCCCCHHHHHCCCCCCCEEECCCHHHHCCCCHHHHHHHHHHHCCHHHH
SDDLATIAFIKETYHKVEVEKR
HHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure 
SRILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCCCCC
NGQGPIISREQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVCD
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEE
FEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISMAGD
CCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACGTATAF
CEEEEEECCHHHHCCCCHHHHHCCCCCCCEEECCCHHHHCCCCHHHHHHHHHHHCCHHHH
SDDLATIAFIKETYHKVEVEKR
HHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]