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The map label for this gene is murA [H]

Identifier: 21910038

GI number: 21910038

Start: 552520

End: 553791

Strand: Direct

Name: murA [H]

Synonym: SpyM3_0502

Alternate gene names: 21910038

Gene position: 552520-553791 (Clockwise)

Preceding gene: 21910037

Following gene: 21910039

Centisome position: 29.07

GC content: 41.35

Gene sequence:

>1272_bases
GTGGATAAAATAATCATTGAAGGTGGTCAAACACGCTTAGAAGGAGAAGTTGTTATTGAGGGTGCTAAAAACGCAGTTCT
TCCTTTACTGGCAGCATCTATTTTACCTTCAAAAGGAAAAACAATTCTTAGAAATGTTCCTATTCTATCTGATGTTTTTA
CCATGAATAACGTGGTACGTGGTTTAGATATTCGTGTTGATTTTAATGAAGCAGCTAACGAAATCACAGTTGATGCCTCA
GGACACATTTTAGATGAAGCCCCTTACGAGTACGTGAGCCAAATGCGTGCCTCTATTGTTGTTTTAGGACCAATTTTGGC
ACGTAATGGCCACGCAAAAGTATCAATGCCTGGAGGCTGTACGATTGGCAGTAGGCCTATTAATTTGCACTTAAAAGGAT
TAGAGGCTATGGGGGCAACGATTACTCAAAAAGGTGGAGATATTACCGCTCAAGCAGATCGACTGCAAGGTGCCATGATT
TATATGGACTTCCCATCTGTAGGAGCTACCCAAAACTTGATGATGGCTGCCACTTTAGCTGATGGTGTGACCACTATTGA
AAATGCTGCTCGTGAGCCTGAAATTGTTGATTTAGCTCAATTTTTGAATAAAATGGGAGCTAGAATTCGTGGTGCTGGAA
CAGAGACGTTAACGATAACAGGCGTCACAAGTCTTCATGGGGTGGAGCACGATGTGGTTCAAGACCGTATTGAAGCAGGT
ACTTTTATGGTTGCAGCGGCGATGACTTCAGGCAATGTTTTGATTAGAGATGCTGTTTGGGAACATAATCGTCCATTGAT
TTCAAAATTAATGGAAATGGGTGTTTCTGTAACAGAAGAAGAATATGGTATTCGCGTTCAAGCAAACACGCCAAAGCTCA
AACCTGTAACGGTTAAAACCTTGCCTCATCCAGGTTTTCCAACAGACATGCAAGCTCAATTTACAGCTTTAATGGCAGTG
GTCAATGGAGAGTCTACTATGGTTGAAACTGTCTTTGAAAATCGATTTCAACATCTGGAAGAAATGCGACGCATGGGCTT
ACAATCTGAAATCCTTAGAGAAACTGCCATGATTCATGGTGGAAGACAACTGCAAGGTGCTCCTGTGATGTCAACAGATT
TACGTGCCAGTGCTGCCCTTATCTTGACAGGGATTGTTGCTCAAGGAGTTACAATAGTTAATAATTTGGTTCATTTAGAT
CGTGGCTACTATCAATTTCATGAAAAATTAGCAAAGCTTGGAGCTACTATTAGTCGTAGCAGTGAGGTCTAG

Upstream 100 bases:

>100_bases
CAAATTAGCCAGACGCTCTTTTTTGAGTTCCGCTAATACTGGAATAAAAGAAGTATGGTATAATTTTACTACGACTAAGA
GATAGATAAGGGAGAAAATT

Downstream 100 bases:

>100_bases
CTTATGACAAATGGTTTAAAATATGTCTTAGAACAAATGTTATTACTTTTAGTAATTGCTGCCTTGGCGTGTCTTTTTTT
AGCCATTGGACTTATGATTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDAS
GHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAG
TFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAV
VNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLD
RGYYQFHEKLAKLGATISRSSEV

Sequences:

>Translated_423_residues
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDAS
GHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAG
TFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAV
VNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLD
RGYYQFHEKLAKLGATISRSSEV
>Mature_423_residues
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDAS
GHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAG
TFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAV
VNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLD
RGYYQFHEKLAKLGATISRSSEV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=49.047619047619, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45601; Mature: 45601

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVR
CCCEEEECCCCEECCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHC
GLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGC
CEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHCEEEEEHHHCCCCCEEEECCCCC
TIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMIYMDFPSVGATQNLMMAATLA
EECCCCEEEEEECHHHHCCEEECCCCCEEEEHHHCCCEEEEEECCCCCCCCHHEEEHHHH
DGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAG
CCHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCEEEEEEEHHHCCCHHHHHHHHHHCC
TFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKT
EEEEEEEECCCCEEEEECHHCCCCHHHHHHHHCCCEEECHHCCEEEECCCCCCCEEEEEE
LPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHG
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLDRGYYQFHEKLAKLGATISRS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
SEV
CCC
>Mature Secondary Structure
MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILRNVPILSDVFTMNNVVR
CCCEEEECCCCEECCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHC
GLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGC
CEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHCEEEEEHHHCCCCCEEEECCCCC
TIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMIYMDFPSVGATQNLMMAATLA
EECCCCEEEEEECHHHHCCEEECCCCCEEEEHHHCCCEEEEEECCCCCCCCHHEEEHHHH
DGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLTITGVTSLHGVEHDVVQDRIEAG
CCHHHHHHHCCCCHHHHHHHHHHHHCCEEECCCCCEEEEEEEHHHCCCHHHHHHHHHHCC
TFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVTEEEYGIRVQANTPKLKPVTVKT
EEEEEEEECCCCEEEEECHHCCCCHHHHHHHHCCCEEECHHCCEEEECCCCCCCEEEEEE
LPHPGFPTDMQAQFTALMAVVNGESTMVETVFENRFQHLEEMRRMGLQSEILRETAMIHG
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GRQLQGAPVMSTDLRASAALILTGIVAQGVTIVNNLVHLDRGYYQFHEKLAKLGATISRS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
SEV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]