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The map label for this gene is aroE [H]

Identifier: 21909914

GI number: 21909914

Start: 422354

End: 423226

Strand: Direct

Name: aroE [H]

Synonym: SpyM3_0378

Alternate gene names: 21909914

Gene position: 422354-423226 (Clockwise)

Preceding gene: 21909912

Following gene: 21909915

Centisome position: 22.22

GC content: 27.95

Gene sequence:

>873_bases
ATGTATTCTGCATTGCTTGGTAATCCAGTTGAACATTCTATATCAGATGAATTATTTGAATATCTAAATCACAACATAGG
AGTTCTGGATGAATATAAACATAAAAAAATTTTGGTAGACTCAGTGTGTTTAGAAGATAAAATCAAACATCTGATAAATG
ATCCAAAATGTATTGGATTAAATATAACTTTACCTTATAAAAGAGAGGTAATGAGGTATATTGACAATTTAGACAGAGTA
GCAGAGATAACTGGATCTGTTAACAATATTTATAAATCTGGAAATATAATTACAGGAACTAATACTGATTGGAAAGGTAT
TTATAATACATTAGTTTTCTTTAATATTAGCCATATAACAAAATGTTGTGTTTTAGGCACTGGCGGTACTGCTAGAGCTG
CTATTTTCACTTTACAAAAACTACAAATCTCACCAACAGTTGTATACAGGGAGCCAATTAGTGAGAATACAAGAAGTTTG
ATAAAGAGTTTCCCTGATTTAAAGTATATTACATATAAGGAATTGGCTGATCAACAAATTTTAAATGATATAGAAATCAT
AATAAATACTACACCAGTTGGTATGATAAATTATGAAGAAAGTTTACCTATAAATTTTGATCATTTGGACAATGTTAATT
ATAAAGATAAATACTTTATGGATGTAGTTTTCAATCCTTTACATACGAAACTTCATGAATATTTTGGTAAAAGAGGAGCA
AAAATAATTGATGGTTTATGGGTTTTGATTTTTCAGGGAATTGAAGCATTTTCATTGTGGAGTGATAAAATTAATGGTGG
TAAATATTTTTTTTCAAAAGATGATGTTGTCCTAATTCATACATTTCTAGAAGGGAAGATAAAAGGAAAATGA

Upstream 100 bases:

>100_bases
TCTTTAGATACTCTAAAGACTTATAGGTAATGGTTAGCTCTGTGTAATGCTTGTACTTTATGTTAGTAGTAAACTAATTA
AACCTAGGAGGATGAAATTT

Downstream 100 bases:

>100_bases
CTTTTCATATTACAGTAAATCTTGATGAAATATCAGACAAACTAGATGATTCATTGAAATTTTTAAATAGATTATCAATT
AAAAGTTGTGAATTACGAAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MYSALLGNPVEHSISDELFEYLNHNIGVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRV
AEITGSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHITKCCVLGTGGTARAAIFTLQKLQISPTVVYREPISENTRSL
IKSFPDLKYITYKELADQQILNDIEIIINTTPVGMINYEESLPINFDHLDNVNYKDKYFMDVVFNPLHTKLHEYFGKRGA
KIIDGLWVLIFQGIEAFSLWSDKINGGKYFFSKDDVVLIHTFLEGKIKGK

Sequences:

>Translated_290_residues
MYSALLGNPVEHSISDELFEYLNHNIGVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRV
AEITGSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHITKCCVLGTGGTARAAIFTLQKLQISPTVVYREPISENTRSL
IKSFPDLKYITYKELADQQILNDIEIIINTTPVGMINYEESLPINFDHLDNVNYKDKYFMDVVFNPLHTKLHEYFGKRGA
KIIDGLWVLIFQGIEAFSLWSDKINGGKYFFSKDDVVLIHTFLEGKIKGK
>Mature_290_residues
MYSALLGNPVEHSISDELFEYLNHNIGVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRV
AEITGSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHITKCCVLGTGGTARAAIFTLQKLQISPTVVYREPISENTRSL
IKSFPDLKYITYKELADQQILNDIEIIINTTPVGMINYEESLPINFDHLDNVNYKDKYFMDVVFNPLHTKLHEYFGKRGA
KIIDGLWVLIFQGIEAFSLWSDKINGGKYFFSKDDVVLIHTFLEGKIKGK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=280, Percent_Identity=27.8571428571429, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789675, Length=268, Percent_Identity=24.6268656716418, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320332, Length=273, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 33196; Mature: 33196

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSALLGNPVEHSISDELFEYLNHNIGVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
NITLPYKREVMRYIDNLDRVAEITGSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHIT
EEECCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCHHHHHHHHHEEEHHHHH
KCCVLGTGGTARAAIFTLQKLQISPTVVYREPISENTRSLIKSFPDLKYITYKELADQQI
EEEEECCCCCHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHH
LNDIEIIINTTPVGMINYEESLPINFDHLDNVNYKDKYFMDVVFNPLHTKLHEYFGKRGA
HCCEEEEEECCCCEEEECCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
KIIDGLWVLIFQGIEAFSLWSDKINGGKYFFSKDDVVLIHTFLEGKIKGK
HHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCEECCC
>Mature Secondary Structure
MYSALLGNPVEHSISDELFEYLNHNIGVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
NITLPYKREVMRYIDNLDRVAEITGSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHIT
EEECCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCHHHHHHHHHEEEHHHHH
KCCVLGTGGTARAAIFTLQKLQISPTVVYREPISENTRSLIKSFPDLKYITYKELADQQI
EEEEECCCCCHHHHHHHHHHEECCCEEEEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHH
LNDIEIIINTTPVGMINYEESLPINFDHLDNVNYKDKYFMDVVFNPLHTKLHEYFGKRGA
HCCEEEEEECCCCEEEECCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
KIIDGLWVLIFQGIEAFSLWSDKINGGKYFFSKDDVVLIHTFLEGKIKGK
HHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]