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The map label for this gene is coaE [H]

Identifier: 21909884

GI number: 21909884

Start: 386797

End: 387390

Strand: Direct

Name: coaE [H]

Synonym: SpyM3_0348

Alternate gene names: 21909884

Gene position: 386797-387390 (Clockwise)

Preceding gene: 21909883

Following gene: 21909885

Centisome position: 20.35

GC content: 41.75

Gene sequence:

>594_bases
ATGATTATTGGCATCACAGGAGGCATTGCATCAGGAAAATCGACTGTGGTTAAGGTCATTAGAAAAGCTGGTTATCAGGT
GATTGATGCGGATCAAGTGGTCCATGACTTGCAAGAAAAAGGCGGTCGCCTTTACGAGGCTCTTAGAGAAGCTTTTGGGA
ATCAGATTTTAAAAGCAGATGGTGAGTTAGATCGCACAAAGCTGTCAGAAATGCTTTTTTCAAACCCAGATAATATGGCA
ACATCCTCAGCCATTCAAAATCAAATCATTAAGGAAGAATTGGCGGCTAAGCGTGACCACTTAGCACAGAGCCAAGCCAT
TTTTTTCATGGATATTCCCCTTTTAATGGAATTGGGCTACCAAGACTGGTTTGATGCGATTTGGCTGGTTTATGTAGATG
CTCAGACACAATTGCAGCGCTTAATGGCTAGAAATCGTTTAGACAAAGGAAAAGCAAGGCAGCGAATAGCCAGTCAGTTA
CCAATAGAGGAAAAAAAGCCCTATGCCAGTCTAGTGATTGATAATAATGGAGACATGGAAACGTTAATAAAGCAAGTACA
ATCTGCGTTGTTGTCATTAGCCAATCCGAGGTAG

Upstream 100 bases:

>100_bases
AAACTGGGAAATCGTGTCCTCGTTGTGGACAGGCTATTGTCAAATTAAAAGTTGGAGGAAGGGGGACGCACATTTGTCCA
AAATGCCAGAAAAAAAGACC

Downstream 100 bases:

>100_bases
CTAAGCTGAGAGATTCGTATCATAGCTGTCAAAATCAAGCTATTTCTGTCTAAAACTAGCTGGTCCCTTTTAAATTAGCG
CATCAAGGGTTATATGTTAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMA
TSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
PIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR

Sequences:

>Translated_197_residues
MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMA
TSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
PIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR
>Mature_197_residues
MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMA
TSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
PIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=188, Percent_Identity=34.5744680851064, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI191252795, Length=188, Percent_Identity=34.5744680851064, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI205277394, Length=189, Percent_Identity=26.984126984127, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI110227607, Length=189, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI110227605, Length=160, Percent_Identity=29.375, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI110227603, Length=160, Percent_Identity=29.375, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI110227601, Length=160, Percent_Identity=29.375, Blast_Score=84, Evalue=8e-17,
Organism=Escherichia coli, GI1786292, Length=185, Percent_Identity=32.972972972973, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=200, Percent_Identity=35.5, Blast_Score=129, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI25143409, Length=168, Percent_Identity=30.3571428571429, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644728, Length=201, Percent_Identity=35.3233830845771, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24658602, Length=192, Percent_Identity=31.7708333333333, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22075; Mature: 22075

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKAD
CEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCC
GELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGY
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCH
QDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNNGDME
HHHHHHHHHHEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHH
TLIKQVQSALLSLANPR
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKAD
CEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCC
GELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGY
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCH
QDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNNGDME
HHHHHHHHHHEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHH
TLIKQVQSALLSLANPR
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]