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The map label for this gene is sstT [H]

Identifier: 21909773

GI number: 21909773

Start: 276895

End: 278034

Strand: Direct

Name: sstT [H]

Synonym: SpyM3_0237

Alternate gene names: 21909773

Gene position: 276895-278034 (Clockwise)

Preceding gene: 21909771

Following gene: 21909777

Centisome position: 14.57

GC content: 38.16

Gene sequence:

>1140_bases
ATGTTGGGCATTTTGGCTCCTGATCTTACAGGTTTTAGTATTTTAGGAAAGTTATTTGTTGGTGGTTTAAAGGCTATCGC
ACCTTTGCTTGTATTTGCTTTGGTTTCCCAAGCCATCTCCCATCAGAAAAAAGGGAAACAGACTAATATGACATTAATCA
TTGTTCTGTATTTATTTGGTACCTTTGCGTCAGCTTTAGTAGCAGTACTGACAGCTTATCTATTCCCTTTGACGTTAGTG
TTAAATACACCTGTAAATACAGAATTATCACCACCTCAAGGTGTTGCTGAAGTTTTTCAGTCACTTCTATTAAAATTAGT
GGATAATCCGATCAATGCTTTAGCTACTGCCAATTATATTGGTGTGCTATCATGGGCAATTATTTTTGGACTAGCATTAA
AGGCTGCAAGTCAAGAAACAAAGCATCTTATAAAAACAGCGGCAGAAGTTACTTCACAAATAGTTGTTTGGATCATCAAT
CTGGCACCTATTGGGATTATGAGTCTGGTGTTCACTACGATTTCTGAAAACGGTGTTGGAATCTTATCTGATTATGCTTT
TTTGATACTAGTTTTAGTAGGAACAATGGTTTTTGTCGCCTTAGTGGTTAATCCACTTATTGCGGTTTTGATTACACGAC
AAAATCCTTATCCCCTTGTCTTGAGATGTTTACGTGAGTCAGGTCTTACAGCATTTTTCACACGAAGTTCTGCAGCCAAT
ATTCCAGTCAATATGCAATTATGCCAAAAAATTGGATTGAGTAAAGATACTTATTCAGTGTCAATTCCACTTGGAGCAAC
TATTAATATGGGTGGGGCAGCAATTACCATCAATGTCCTAACGCTTGCTGCTGTACACACTTTTGGTATTCCTATTGATT
TTCTAACAGCCCTCTTACTTAGCGTTGTTGCTGCTGTCTCTGCTTGTGGTGCTTCTGGTGTTGCTGGGGGATCGTTGTTA
CTTATTCCTGTAGCATGTAGTTTGTTTGGCATTTCAAATGATCTTGCGATGCAGGTGGTTGGTGTTGGTTTTATTGTTGG
TGTTATCCAGGATTCTTGTGAGACAGCCTTAAATTCGTCAACCGATGTTCTTTTTACAGCTATTGCTGAAAATGCTTTTT
GGAAACGTAAAAAAGCATAG

Upstream 100 bases:

>100_bases
TGTAACTTTAGTAAGGATGTAACGTATGAAAAAAATATATGATTTATGGGTTAGGGTTAGTCTAATCAAAAAAATAGGTA
TCGGTGTTGTAATAGGAGTC

Downstream 100 bases:

>100_bases
CTAGATTTAACATAGTAAAAAACATCCTTGGAAAACGCCAAGGATGTTTTTTTACTATTTAAGATAGCCAAGATAATCAA
ATTTTTCAAAGGTGTGGTCA

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPLTLV
LNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIIN
LAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAAN
IPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSACGASGVAGGSLL
LIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWKRKKA

Sequences:

>Translated_379_residues
MLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPLTLV
LNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIIN
LAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAAN
IPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSACGASGVAGGSLL
LIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWKRKKA
>Mature_379_residues
MLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPLTLV
LNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIIN
LAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAAN
IPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSACGASGVAGGSLL
LIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWKRKKA

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI223468564, Length=261, Percent_Identity=31.8007662835249, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI223468566, Length=261, Percent_Identity=31.8007662835249, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI5032093, Length=261, Percent_Identity=31.8007662835249, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI21314632, Length=274, Percent_Identity=30.6569343065693, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI169790839, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4827012, Length=268, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789473, Length=373, Percent_Identity=59.5174262734584, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1789947, Length=254, Percent_Identity=29.5275590551181, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790514, Length=309, Percent_Identity=24.5954692556634, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996953, Length=290, Percent_Identity=24.4827586206897, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=270, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=285, Percent_Identity=25.9649122807018, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=285, Percent_Identity=25.9649122807018, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=267, Percent_Identity=24.7191011235955, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583025, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17137668, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24583023, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 39730; Mature: 39730

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCC
IPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLL
CCCCHHHHHHCCCCCCCEEEEECCCCEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHHHH
SVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSS
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDVLFTAIAENAFWKRKKA
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCC
IPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLL
CCCCHHHHHHCCCCCCCEEEEECCCCEEECCCCEEEHHHHHHHHHHHHCCCHHHHHHHHH
SVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSS
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TDVLFTAIAENAFWKRKKA
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]