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The map label for this gene is ntpD [H]

Identifier: 21909658

GI number: 21909658

Start: 144300

End: 144926

Strand: Direct

Name: ntpD [H]

Synonym: SpyM3_0122

Alternate gene names: 21909658

Gene position: 144300-144926 (Clockwise)

Preceding gene: 21909657

Following gene: 21909661

Centisome position: 7.59

GC content: 38.28

Gene sequence:

>627_bases
ATGGCACGATTAAATGTTAAACCAACACGCATGGAACTTAGTAACTTGAAAAATCGCTTGAAGACAGCTACAAGAGGTCA
TAAATTATTAAAGGACAAGCGAGATGAATTGATGCGCCGCTTCGTTGATTTAATTCGTGAAAACAATGAGCTTCGGCAAA
CTATCGAAAAAGAACTTGCTGCCAATATGAAGGAGTTTGTCTTGGCAAAAGCATCTGAAAATAGTCTAATGGTAGAAGAA
CTCTTTGCTGTTCCGGTCCATGAAGTGACCTTATGGATTGATATTGAAAATATCATGAGTGTCAATGTGCCTAAATTTCA
TGTCCAGTCTAATACGGCAAGAGAGCAAGAACAAGGTGAGTTTGCTTATAGTTACCTCAGCTCAAATAGTGAGATGGACA
ATACTATCCAAAAGACAAAAGAACTATTAGAAAAGCTCTTACGGTTAGCTGAAGTTGAAAAAACTTGTCAACTAATGGCT
GATGACATTGAAAAGACTAGACGTCGCGTCAATGGCTTAGAGTATGCTATTATCCCGCAACTGGAAGAGACGATTCACTA
CATTGAGTTGAAATTAGAAGAGGCCGAGCGTGCTAGCCTTGTTCGTATTATGAAAATAACATCATAA

Upstream 100 bases:

>100_bases
GTTATTTGCCTAAAGCAGATACCACGATGACAAAGGTTTTTGTTGCAAATGATTGAGTTGACCATGCAATTTCAAGCCCT
TGACGAAAGGAGTTATATCA

Downstream 100 bases:

>100_bases
AAGATAAGTGCTATATCAAACAAGGCGATTATTCGTTAAGTAGTAAAAAAGCAAGCCATCAAAGGGATTAACCTAACTGA
TGACTTGCTTTTTAAGTAGC

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDLIRENNELRQTIEKELAANMKEFVLAKASENSLMVEE
LFAVPVHEVTLWIDIENIMSVNVPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
DDIEKTRRRVNGLEYAIIPQLEETIHYIELKLEEAERASLVRIMKITS

Sequences:

>Translated_208_residues
MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDLIRENNELRQTIEKELAANMKEFVLAKASENSLMVEE
LFAVPVHEVTLWIDIENIMSVNVPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
DDIEKTRRRVNGLEYAIIPQLEETIHYIELKLEEAERASLVRIMKITS
>Mature_207_residues
ARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDLIRENNELRQTIEKELAANMKEFVLAKASENSLMVEEL
FAVPVHEVTLWIDIENIMSVNVPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMAD
DIEKTRRRVNGLEYAIIPQLEETIHYIELKLEEAERASLVRIMKITS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family [H]

Homologues:

Organism=Homo sapiens, GI7706757, Length=209, Percent_Identity=28.7081339712919, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17553636, Length=213, Percent_Identity=31.924882629108, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320784, Length=211, Percent_Identity=28.9099526066351, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI20128937, Length=207, Percent_Identity=28.5024154589372, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355551, Length=208, Percent_Identity=28.3653846153846, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002699 [H]

Pfam domain/function: PF01813 ATP-synt_D [H]

EC number: 3.6.3.14

Molecular weight: Translated: 24333; Mature: 24201

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDLIRENNELRQTIEKELA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVNVPKFHVQSNTAREQEQGE
HHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEEEEHHHHHHCCCCEEEECCCCHHHHHHHH
FAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMADDIEKTRRRVNGLEYAIIPQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
LEETIHYIELKLEEAERASLVRIMKITS
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDLIRENNELRQTIEKELA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVNVPKFHVQSNTAREQEQGE
HHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEEEEHHHHHHCCCCEEEECCCCHHHHHHHH
FAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMADDIEKTRRRVNGLEYAIIPQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
LEETIHYIELKLEEAERASLVRIMKITS
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]