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The map label for this gene is 21909636

Identifier: 21909636

GI number: 21909636

Start: 120502

End: 121536

Strand: Direct

Name: 21909636

Synonym: SpyM3_0100

Alternate gene names: NA

Gene position: 120502-121536 (Clockwise)

Preceding gene: 21909635

Following gene: 21909637

Centisome position: 6.34

GC content: 33.82

Gene sequence:

>1035_bases
ATGAAAAAAAACAAATTATTACTTGCTACTGCAATCTTAGCAACTGCTTTAGGAACAGCTTCTTTAAATCAAAACGTAAA
AGCTGAGACGGCAGGAGTGTCCGAAAATGCAAAATTAATAGTAAAAAAGACATTTGACTCTTATACAGACAATGAAGTTT
TAATGCCAAAAGCTGATTATACTTTTAAAGTAGAGGCAGATAGTACAGCTAGTGGCAAAACGAAAGACGGTTTAGAGATT
AAGCCAGGTATTGTTAATGGTTTAACAGAACAGATTATCAGCTATACTAATACTGATAAACCAGATAGTAAAGTTAAAAG
TACAGAGTTTGATTTTTCAAAAGTAGTATTCCCTGGTATTGGTGTTTACCGCTATACTGTTTCAGAAAAACAAGGTGATG
TTGAAGGAATTACCTACGATACTAAGAAGTGGACAGTAGATGTTTATGTTGGAAACAAAGAAGGTGGTGGTTTTGAACCT
AAGTTTATTGTATCTAAGGAACAAGGAACAGACGTCAAAAAACCAGTTAATTTTAACAACTCGTTTGCAACTACTTCGTT
AAAAGTTAAGAAGAATGTATCGGGGAATACTGGAGAATTGCAAAAAGAATTTGACTTTACATTGACGCTTAATGAAAGCA
CGAATTTTAAAAAAGATCAAATTGTTTCTTTACAAAAAGGAAACGAGAAATTTGAAGTTAAGATTGGTACTCCCTACAAG
TTTAAACTCAAAAATGGGGAATCTATTCAACTAGACAAGTTACCAGTTGGTATTACTTATAAAGTCAATGAAATGGAAGC
TAATAAAGATGGGTATAAAACAACAGCATCCTTGAAAGAGGGAGATGGTCAATCTAAAATGTATCAATTGGATATGGAAC
AAAAAACAGACGAATCTGCTGACGAAATCGTTGTCACAAATAAGCGTGACACTCAAGTTCCAACTGGTGTTGTAGGCACC
CTTGCTCCATTTGCAGTTCTTAGCATTGTGGCTATTGGTGGAGTTATCTATATTACAAAACGTAAAAAAGCTTAA

Upstream 100 bases:

>100_bases
ACAGTCGTTATTATGGGGCGTTACCCATCAATCAAATCAAAGGGAAAATCTCAACTCTATTAAGAGTGAGAGGAATTTAA
AAAATTTGGAGAGAGAAAAA

Downstream 100 bases:

>100_bases
GTGATTAGTCAAAGAATGGTGATGACAATTGTACAGGTTATCAATAAAGCCATTGATACTCTCATTCTTATCTTTTGTTT
AGTCGTACTATTTTTAGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Lancefield T antigen; Pilus backbone structural protein [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKKNKLLLATAILATALGTASLNQNVKAETAGVSENAKLIVKKTFDSYTDNEVLMPKADYTFKVEADSTASGKTKDGLEI
KPGIVNGLTEQIISYTNTDKPDSKVKSTEFDFSKVVFPGIGVYRYTVSEKQGDVEGITYDTKKWTVDVYVGNKEGGGFEP
KFIVSKEQGTDVKKPVNFNNSFATTSLKVKKNVSGNTGELQKEFDFTLTLNESTNFKKDQIVSLQKGNEKFEVKIGTPYK
FKLKNGESIQLDKLPVGITYKVNEMEANKDGYKTTASLKEGDGQSKMYQLDMEQKTDESADEIVVTNKRDTQVPTGVVGT
LAPFAVLSIVAIGGVIYITKRKKA

Sequences:

>Translated_344_residues
MKKNKLLLATAILATALGTASLNQNVKAETAGVSENAKLIVKKTFDSYTDNEVLMPKADYTFKVEADSTASGKTKDGLEI
KPGIVNGLTEQIISYTNTDKPDSKVKSTEFDFSKVVFPGIGVYRYTVSEKQGDVEGITYDTKKWTVDVYVGNKEGGGFEP
KFIVSKEQGTDVKKPVNFNNSFATTSLKVKKNVSGNTGELQKEFDFTLTLNESTNFKKDQIVSLQKGNEKFEVKIGTPYK
FKLKNGESIQLDKLPVGITYKVNEMEANKDGYKTTASLKEGDGQSKMYQLDMEQKTDESADEIVVTNKRDTQVPTGVVGT
LAPFAVLSIVAIGGVIYITKRKKA
>Mature_344_residues
MKKNKLLLATAILATALGTASLNQNVKAETAGVSENAKLIVKKTFDSYTDNEVLMPKADYTFKVEADSTASGKTKDGLEI
KPGIVNGLTEQIISYTNTDKPDSKVKSTEFDFSKVVFPGIGVYRYTVSEKQGDVEGITYDTKKWTVDVYVGNKEGGGFEP
KFIVSKEQGTDVKKPVNFNNSFATTSLKVKKNVSGNTGELQKEFDFTLTLNESTNFKKDQIVSLQKGNEKFEVKIGTPYK
FKLKNGESIQLDKLPVGITYKVNEMEANKDGYKTTASLKEGDGQSKMYQLDMEQKTDESADEIVVTNKRDTQVPTGVVGT
LAPFAVLSIVAIGGVIYITKRKKA

Specific function: Major component of the pilus. A stack of the pilin subunits, joined by intermolecular isopeptide bonds, forms the pilus. The pilus is required for bacterial adhesion to host cells, for bacterial aggregation, and for biofilm formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor. Fimbrium. Note=Attached to the cell wall by a peptidoglycan anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Streptococcus pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017503
- InterPro:   IPR022464 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37738; Mature: 37738

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNKLLLATAILATALGTASLNQNVKAETAGVSENAKLIVKKTFDSYTDNEVLMPKADY
CCCCEEEHHHHHHHHHHCCHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCE
TFKVEADSTASGKTKDGLEIKPGIVNGLTEQIISYTNTDKPDSKVKSTEFDFSKVVFPGI
EEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
GVYRYTVSEKQGDVEGITYDTKKWTVDVYVGNKEGGGFEPKFIVSKEQGTDVKKPVNFNN
EEEEEEECCCCCCCCCEEEECCEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCC
SFATTSLKVKKNVSGNTGELQKEFDFTLTLNESTNFKKDQIVSLQKGNEKFEVKIGTPYK
CEEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCHHHEEEEECCCEEEEEEECCCEE
FKLKNGESIQLDKLPVGITYKVNEMEANKDGYKTTASLKEGDGQSKMYQLDMEQKTDESA
EEECCCCEEEEECCCEEEEEEEECEECCCCCCEEEECCCCCCCCCEEEEEECHHCCCCCC
DEIVVTNKRDTQVPTGVVGTLAPFAVLSIVAIGGVIYITKRKKA
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure
MKKNKLLLATAILATALGTASLNQNVKAETAGVSENAKLIVKKTFDSYTDNEVLMPKADY
CCCCEEEHHHHHHHHHHCCHHCCCCCEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCE
TFKVEADSTASGKTKDGLEIKPGIVNGLTEQIISYTNTDKPDSKVKSTEFDFSKVVFPGI
EEEEECCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCC
GVYRYTVSEKQGDVEGITYDTKKWTVDVYVGNKEGGGFEPKFIVSKEQGTDVKKPVNFNN
EEEEEEECCCCCCCCCEEEECCEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCC
SFATTSLKVKKNVSGNTGELQKEFDFTLTLNESTNFKKDQIVSLQKGNEKFEVKIGTPYK
CEEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCHHHEEEEECCCEEEEEEECCCEE
FKLKNGESIQLDKLPVGITYKVNEMEANKDGYKTTASLKEGDGQSKMYQLDMEQKTDESA
EEECCCCEEEEECCCEEEEEEEECEECCCCCCEEEECCCCCCCCCEEEEEECHHCCCCCC
DEIVVTNKRDTQVPTGVVGTLAPFAVLSIVAIGGVIYITKRKKA
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]