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The map label for this gene is adcB [H]

Identifier: 21909607

GI number: 21909607

Start: 89134

End: 89949

Strand: Direct

Name: adcB [H]

Synonym: SpyM3_0071

Alternate gene names: 21909607

Gene position: 89134-89949 (Clockwise)

Preceding gene: 21909606

Following gene: 21909610

Centisome position: 4.69

GC content: 38.6

Gene sequence:

>816_bases
ATGCTTGATATTTTATCCTATGATTTCATGCAACGGGCGGTAATGGCGGTAGTTGCCATTAGTATTTTTGCTCCGATTTT
AGGTATTTTCCTTATTTTACGTCGTCAAAGTTTGATGAGCGATACCCTTAGTCATGTTTCTTTGGCTGGGGTAGCGCTTG
GGGTAGTTCTTGGTATTTCACCAACCATCACTACTATTATTGTTGTGGTTTTAGCTGCTATTTTGTTAGAATACCTGCGT
GTAGTTTACAAACACTACATGGAGATTTCAACGGCGATTTTGATGTCACTTGGCTTGGCCCTATCTCTGATTATTATGAG
TAAGTCGCATAGTTCATCAAGCATGAGTTTAGAACAATACCTTTTTGGATCGATCATCACGATTAGTATGGAACAAGTTG
TCGCCTTGTTTGCTATTGCTGCGATTATTTTAATCTTGACCGTTCTCTTCATTAGACCGATGTACATTCTGACCTTTGAT
GAAGATACTGCTTTTGTAGATGGTTTGCCCGTTCGCTTGATGTCTGTTCTATTCAATATCGTCACTGGGGTTGCTATTGC
TTTGACCATTCCAGCAGCAGGAGCACTTTTGGTTTCTACCATTATGGTCTTGCCAGCAAGTATCGCAATGAGATTGGGTA
AAAACTTTAAAACAGTTATCTTACTGGGAATTGTCATCGGTTTTAGCGGTATGTTATCTGGTATTTTCTTATCTTATTTC
TTTGAAACGCCAGCTAGTGCCACTATTACCATGATTTTCATTAGCATTTTCCTCTTAGTTAGTCTAGGTGGAATGCTTAA
AAAACGGTTATTTTAA

Upstream 100 bases:

>100_bases
GCTGATCGGAACATTCATTTAGTCAGAAATCAAAAACTTCCTTGGCGTTGTTTCAACATTCATGAAGTTGAAACAGATGA
CGAAAAAGGAGGTCATGGTC

Downstream 100 bases:

>100_bases
TAAGAAAAATCCTCACATGTTTAACATGTGAGGATTTATTTATAAATGCTTTAAAAAGGGGGCAAGGTCCCAATTTTCTT
GATTAATGGTGATGCCCTCC

Product: putative ABC transporter (permease)

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLSHVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLR
VVYKHYMEISTAILMSLGLALSLIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKTVILLGIVIGFSGMLSGIFLSYF
FETPASATITMIFISIFLLVSLGGMLKKRLF

Sequences:

>Translated_271_residues
MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLSHVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLR
VVYKHYMEISTAILMSLGLALSLIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKTVILLGIVIGFSGMLSGIFLSYF
FETPASATITMIFISIFLLVSLGGMLKKRLF
>Mature_271_residues
MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLSHVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLR
VVYKHYMEISTAILMSLGLALSLIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKTVILLGIVIGFSGMLSGIFLSYF
FETPASATITMIFISIFLLVSLGGMLKKRLF

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=245, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 29283; Mature: 29283

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLSHVSLAGVALGVVLGIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALSLIIMSKSHSSSSMSLEQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFDEDTAFVDGLPVRLMSVLFNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHCCHHHHHHHHHHHH
VTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKTVILLGIVIGFSGMLSGIFLSYF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FETPASATITMIFISIFLLVSLGGMLKKRLF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLSHVSLAGVALGVVLGIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALSLIIMSKSHSSSSMSLEQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFDEDTAFVDGLPVRLMSVLFNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHCCHHHHHHHHHHHH
VTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKTVILLGIVIGFSGMLSGIFLSYF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FETPASATITMIFISIFLLVSLGGMLKKRLF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]