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The map label for this gene is yieH [H]

Identifier: 218931084

GI number: 218931084

Start: 4629510

End: 4630178

Strand: Direct

Name: yieH [H]

Synonym: YPO4108

Alternate gene names: 218931084

Gene position: 4629510-4630178 (Clockwise)

Preceding gene: 218931080

Following gene: NA

Centisome position: 99.48

GC content: 47.68

Gene sequence:

>669_bases
GTGAATCAGATTCAATGCGTCATGTTCGATTGCGATGGCACCTTGGTCGACAGCGAAGTCCTGTGTTGCCAGGCTTACGT
CCTAATGTTTGCTCACTACAATATTCACCTGTCGTTAGAAGAGGTGATTAAACGCTTTAAAGGCGTAAAACTGTATGAAA
TTGTTGGGATAGTCTGTAAAGAATATGGATTAGACCAACCGATAAAGGTACTGGAAAAGCTTTACCGTGAAGAAGTAGCA
CGTTTATTCGATGCCGAATTACAGCCTATAGCCGGTGTGAAAGCGCTGTTAGAGCAAATCGTGTTACCCGTCTGTGTGGT
ATCCAACGGGCCAGTCAGCAAAATGCAGCACTCGCTTGGCCTAACCGGATTACTGCCATTCTTTGAGGACCGGCTTTATA
GCAGCTATGATATTCAGCGTTGGAAGCCTGATCCGGCTCTGATTTACCATGCCGCTGAACATATGCAGGTTGCCGCTGAG
CACTGTATTTTGATTGAAGATTCTGCCGCAGGTGCCCAGGCCGGGATTGCCGCCGGTATTCCGGTGTTTTATTACTGTGC
CGATCCGCACAACCAACCGATTAACCACCCGCTAGTGACTACTTTCACGGATATTCAGCAACTGCCTCATTTGTGGAAGG
AAAGAGGCTGGCATATCACCCGCGATTAA

Upstream 100 bases:

>100_bases
TATTAATTTTATTACTAACAGGCTAATAAACATCGCTTTATTTATTAGGATGGTTAGAGTGGGATTAACTGATGTCTATC
TTTTTTAAAGGATTAGTTGC

Downstream 100 bases:

>100_bases
TTTACCTGTAATGAATTAGCCTGCCTATAATCAATTAACTCGATTGCAGTGTTAGCTTGTTACACCACCAGCGCCATGAA
CGTGCCATGGAGCTTTGGTT

Product: 6-phosphogluconate phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIVCKEYGLDQPIKVLEKLYREEVA
RLFDAELQPIAGVKALLEQIVLPVCVVSNGPVSKMQHSLGLTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAE
HCILIEDSAAGAQAGIAAGIPVFYYCADPHNQPINHPLVTTFTDIQQLPHLWKERGWHITRD

Sequences:

>Translated_222_residues
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIVCKEYGLDQPIKVLEKLYREEVA
RLFDAELQPIAGVKALLEQIVLPVCVVSNGPVSKMQHSLGLTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAE
HCILIEDSAAGAQAGIAAGIPVFYYCADPHNQPINHPLVTTFTDIQQLPHLWKERGWHITRD
>Mature_222_residues
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIVCKEYGLDQPIKVLEKLYREEVA
RLFDAELQPIAGVKALLEQIVLPVCVVSNGPVSKMQHSLGLTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAE
HCILIEDSAAGAQAGIAAGIPVFYYCADPHNQPINHPLVTTFTDIQQLPHLWKERGWHITRD

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=220, Percent_Identity=62.7272727272727, Blast_Score=296, Evalue=6e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25123; Mature: 25123

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIVCK
CCCEEEEEEECCCCEECHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCHHHHHHHHHHH
EYGLDQPIKVLEKLYREEVARLFDAELQPIAGVKALLEQIVLPVCVVSNGPVSKMQHSLG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHCC
LTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAEHCILIEDSAAGAQAGIAAGI
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHCCC
PVFYYCADPHNQPINHPLVTTFTDIQQLPHLWKERGWHITRD
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNQIQCVMFDCDGTLVDSEVLCCQAYVLMFAHYNIHLSLEEVIKRFKGVKLYEIVGIVCK
CCCEEEEEEECCCCEECHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCHHHHHHHHHHH
EYGLDQPIKVLEKLYREEVARLFDAELQPIAGVKALLEQIVLPVCVVSNGPVSKMQHSLG
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHCC
LTGLLPFFEDRLYSSYDIQRWKPDPALIYHAAEHMQVAAEHCILIEDSAAGAQAGIAAGI
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHCCC
PVFYYCADPHNQPINHPLVTTFTDIQQLPHLWKERGWHITRD
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]