Click here to switch to the map view.

The map label for this gene is nrdD [H]

Identifier: 218930468

GI number: 218930468

Start: 3860916

End: 3863054

Strand: Direct

Name: nrdD [H]

Synonym: YPO3454

Alternate gene names: 218930468

Gene position: 3860916-3863054 (Clockwise)

Preceding gene: 218930467

Following gene: 218930469

Centisome position: 82.96

GC content: 49.32

Gene sequence:

>2139_bases
GTGAAAACAGTAGTGATTAAACGGGACGGCTGCCAGGTACCTTTTGATGAAGTTCGTATCAAAGAGGCTGTTGAGCGCGC
AGCATTAGCTGTTGGCGTGGTCGATGCCGATTATTGTGCAACCGTTGCCCGAGTGGTCGCTCAAACGATGGAAAACCAGC
CGAAGGTTGATATCCGTGAAATTCAAAACGCGGTAGAAAACCAACTGATGGCGGGTCAATACAAACAGTTAGCCCGGGCT
TACATCGAATATCGTCATGATCGTGATATCTCACGGGAACTGCGTGGCCGCTTGAATCAGGAAATTCAAGGGTTAGTGGA
GCAAAGCAACAAAGCACTGCTGAACGAAAATGCCAACAAAGACAGCAAAGTGATCCCTACCCAGCGCGATCTGTTGGCCG
GTATTGTTGCCAAGCACTACGCTAAACAGCATCTTTTGCCCCGCGATGTGGTGCTGGCCCATGAGCGCGGCGAAATTCAC
TATCATGATCTGGATTACGCGCCGTTCTTCCCGATGTTCAACTGTATGTTGATTGATTTGGAAGGCATGTTAACCCAAGG
TTTTAAAATGGGTAATGCGGAAATAGAGCCGCCAAAATCCATTTCTACCGCAACCGCTGTAACCGCACAAATTATCGCGC
AGGTTGCCAGCCATATCTATGGTGGCACCACCATTAACCGTATTGATGAAGTTTTGGCCCCTTTTGTCACGGAAAGCTTT
AATAAACATAAGGCTGTCGCCGAAGAGTGGCAGATCCCTGATGTTGCAGGTTATGCCATGTCGCGTACCGAAAAAGAGTG
TTACGACGCCTTCCAGTCACTGGAGTATGAGGTCAATACACTGCATACCGCGAATGGCCAAACGCCCTTCGTCACCTTCG
GTTTTGGCTTGGGCACCAGTTGGCAATCACGCATGATCCAGCAGGCTATTTTGCGTAATCGTATTGCGGGCTTGGGTAAA
AACCGTAAAACGGCGGTATTCCCAAAACTGGTATTTGCTATCCGCGATGGCCTGAACCACAAATTTGGCGATGCTAACTA
CGATATCAAACAGTTGGCGCTGGAGTGCGCAACCAAGCGCATGTATCCAGATATTCTTAATTATGATCAAGTGGTTAAGG
TCACTGGCTCCTTTAAAACGCCAATGGGCTGCCGTAGCTTCCTCGGCGTGTATGAGGAGGAGGGTCAACAAATCCACGAT
GGCCGGAATAATTTGGGAGTGATCAGCCTTAATCTGCCACGTATCGCGTTGGAAGCAAAAGGGGATGAAAACCAATTTTG
GCAGTTGCTGGATGAGCGCCTGCTTATCGCGAAAAAAGCGCTAATGACCCGAATTGCCCGTTTAGAAGGGATCAAAGCAC
GAGTCGCCCCCATTCTGTATATGGAAGGTGCTTGCGGTGTACGCTTACAAGCGGATGATAATATTGCCGAAATCTTTAAA
AATGGCCGTGCGTCGATCTCGCTGGGCTATATCGGGATACATGAAACCATTAATGCCTTATTCGGCCATCAGACCCATCT
CTTTGATGACCAGAAGCTGCGCGAAAAAGCCATCGCCATTGTGGCTCATTTGAAACAGGCTACCGATGATTGGAAAGATG
AAACCGGTTATGCCTTTAGCCTATACAGCACCCCAAGTGAAAACTTGTGTGACCGCTTCTGCCGCCTTGATACCGCTGAA
TTTGGTGTGGTTGAAGGGGTGACGGACAAAGGCTATTACACCAACAGCTTCCATCTGGATGTTGAGAAAAAAGTGAATCC
CTACGACAAACTGGATTTCGAAGCCCCTTATCCGCCGCTGGCTAACGGTGGTTTCATCTGTTACGGCGAATACCCTAATT
TGCAGCACAACATCCGGGCGCTGGAAGACGTCTGGGATTACAGCTACAGCCGGGTTCCTTATTACGGCACCAACACGCCA
ATTGATGAGTGCTATGAATGCGGCTTCACCGGTGAATTCTCTTGTACCAGCAAAGGCTTTACCTGCCCGAAATGCGGCAA
CCATGAGCCATCGAAAGTGTCGGTCACCCGCCGGGTATGTGGTTATTTGGGTAGCCCAGATGCACGGCCATTTAATGCGG
GTAAACAAGAAGAAGTGAAACGCCGGGTGAAACATCTGGCTAACGGGCAGTTGGGCTGA

Upstream 100 bases:

>100_bases
AGTAGTTATCCACAAAAGCATCCACATCCCCCTCGCAGCCCTGATGTGCTGCGGGTTGCCTTGTGGATAACCCTATGCGG
CGGTATACAGGAGTGACATT

Downstream 100 bases:

>100_bases
AACGCTAAGCAGAATATGACCCAAAGCAGTATTACCCAAAACAGTATTACCCAAAATCATTGGCGTTGTAGGTAGGCGAC
AACCTCAGGCCTCGTCAATG

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 712

Protein sequence:

>712_residues
MKTVVIKRDGCQVPFDEVRIKEAVERAALAVGVVDADYCATVARVVAQTMENQPKVDIREIQNAVENQLMAGQYKQLARA
YIEYRHDRDISRELRGRLNQEIQGLVEQSNKALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHLLPRDVVLAHERGEIH
YHDLDYAPFFPMFNCMLIDLEGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESF
NKHKAVAEEWQIPDVAGYAMSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWQSRMIQQAILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDANYDIKQLALECATKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVYEEEGQQIHD
GRNNLGVISLNLPRIALEAKGDENQFWQLLDERLLIAKKALMTRIARLEGIKARVAPILYMEGACGVRLQADDNIAEIFK
NGRASISLGYIGIHETINALFGHQTHLFDDQKLREKAIAIVAHLKQATDDWKDETGYAFSLYSTPSENLCDRFCRLDTAE
FGVVEGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPLANGGFICYGEYPNLQHNIRALEDVWDYSYSRVPYYGTNTP
IDECYECGFTGEFSCTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLANGQLG

Sequences:

>Translated_712_residues
MKTVVIKRDGCQVPFDEVRIKEAVERAALAVGVVDADYCATVARVVAQTMENQPKVDIREIQNAVENQLMAGQYKQLARA
YIEYRHDRDISRELRGRLNQEIQGLVEQSNKALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHLLPRDVVLAHERGEIH
YHDLDYAPFFPMFNCMLIDLEGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESF
NKHKAVAEEWQIPDVAGYAMSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWQSRMIQQAILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDANYDIKQLALECATKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVYEEEGQQIHD
GRNNLGVISLNLPRIALEAKGDENQFWQLLDERLLIAKKALMTRIARLEGIKARVAPILYMEGACGVRLQADDNIAEIFK
NGRASISLGYIGIHETINALFGHQTHLFDDQKLREKAIAIVAHLKQATDDWKDETGYAFSLYSTPSENLCDRFCRLDTAE
FGVVEGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPLANGGFICYGEYPNLQHNIRALEDVWDYSYSRVPYYGTNTP
IDECYECGFTGEFSCTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLANGQLG
>Mature_712_residues
MKTVVIKRDGCQVPFDEVRIKEAVERAALAVGVVDADYCATVARVVAQTMENQPKVDIREIQNAVENQLMAGQYKQLARA
YIEYRHDRDISRELRGRLNQEIQGLVEQSNKALLNENANKDSKVIPTQRDLLAGIVAKHYAKQHLLPRDVVLAHERGEIH
YHDLDYAPFFPMFNCMLIDLEGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESF
NKHKAVAEEWQIPDVAGYAMSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWQSRMIQQAILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKFGDANYDIKQLALECATKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVYEEEGQQIHD
GRNNLGVISLNLPRIALEAKGDENQFWQLLDERLLIAKKALMTRIARLEGIKARVAPILYMEGACGVRLQADDNIAEIFK
NGRASISLGYIGIHETINALFGHQTHLFDDQKLREKAIAIVAHLKQATDDWKDETGYAFSLYSTPSENLCDRFCRLDTAE
FGVVEGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPLANGGFICYGEYPNLQHNIRALEDVWDYSYSRVPYYGTNTP
IDECYECGFTGEFSCTSKGFTCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLANGQLG

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=713, Percent_Identity=85.9747545582048, Blast_Score=1299, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 80040; Mature: 80040

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVVIKRDGCQVPFDEVRIKEAVERAALAVGVVDADYCATVARVVAQTMENQPKVDIRE
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
IQNAVENQLMAGQYKQLARAYIEYRHDRDISRELRGRLNQEIQGLVEQSNKALLNENANK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCC
DSKVIPTQRDLLAGIVAKHYAKQHLLPRDVVLAHERGEIHYHDLDYAPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCEEEECCCCCCHHHHHHEEEEEH
EGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESF
HHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NKHKAVAEEWQIPDVAGYAMSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCEEEEECCCCCC
WQSRMIQQAILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDANYDIKQLALECATKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
MYPDILNYDQVVKVTGSFKTPMGCRSFLGVYEEEGQQIHDGRNNLGVISLNLPRIALEAK
HCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCEEEEECC
GDENQFWQLLDERLLIAKKALMTRIARLEGIKARVAPILYMEGACGVRLQADDNIAEIFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHHH
NGRASISLGYIGIHETINALFGHQTHLFDDQKLREKAIAIVAHLKQATDDWKDETGYAFS
CCCCEEEEEEEEHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LYSTPSENLCDRFCRLDTAEFGVVEGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPL
EECCCCHHHHHHHHHCCCCCCCEEECCCCCCEEECEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNLQHNIRALEDVWDYSYSRVPYYGTNTPIDECYECGFTGEFSCTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
TCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLANGQLG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTVVIKRDGCQVPFDEVRIKEAVERAALAVGVVDADYCATVARVVAQTMENQPKVDIRE
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
IQNAVENQLMAGQYKQLARAYIEYRHDRDISRELRGRLNQEIQGLVEQSNKALLNENANK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCC
DSKVIPTQRDLLAGIVAKHYAKQHLLPRDVVLAHERGEIHYHDLDYAPFFPMFNCMLIDL
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCEEEECCCCCCHHHHHHEEEEEH
EGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTESF
HHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
NKHKAVAEEWQIPDVAGYAMSRTEKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCEEEEECCCCCC
WQSRMIQQAILRNRIAGLGKNRKTAVFPKLVFAIRDGLNHKFGDANYDIKQLALECATKR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
MYPDILNYDQVVKVTGSFKTPMGCRSFLGVYEEEGQQIHDGRNNLGVISLNLPRIALEAK
HCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCEEEEECC
GDENQFWQLLDERLLIAKKALMTRIARLEGIKARVAPILYMEGACGVRLQADDNIAEIFK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCCCEEEECCCCHHHHHH
NGRASISLGYIGIHETINALFGHQTHLFDDQKLREKAIAIVAHLKQATDDWKDETGYAFS
CCCCEEEEEEEEHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LYSTPSENLCDRFCRLDTAEFGVVEGVTDKGYYTNSFHLDVEKKVNPYDKLDFEAPYPPL
EECCCCHHHHHHHHHCCCCCCCEEECCCCCCEEECEEEEEECCCCCCCCCCCCCCCCCCC
ANGGFICYGEYPNLQHNIRALEDVWDYSYSRVPYYGTNTPIDECYECGFTGEFSCTSKGF
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCC
TCPKCGNHEPSKVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLANGQLG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]