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The map label for this gene is argI [H]

Identifier: 218930462

GI number: 218930462

Start: 3852930

End: 3853937

Strand: Direct

Name: argI [H]

Synonym: YPO3446

Alternate gene names: 218930462

Gene position: 3852930-3853937 (Clockwise)

Preceding gene: 218930460

Following gene: 218930464

Centisome position: 82.79

GC content: 49.01

Gene sequence:

>1008_bases
ATGAATCAGTTCTATAAACGTCACTTTCTGAGGTTGTTAGATTTTACCCCCGCTGAAATTATTGCCTTGCTTGATTTAGC
TACTGAATTGAAAAAAGACAAGAAATCTGGCTGTGAACAGCAAAAATTGGTCGGTAAGAATATCGCGCTCATCTTCGAAA
AAGACTCGACTCGCACTCGATGCTCTTTCGAAGTTGCCGCATATGACCAAGGTGCTCGCGTCACTTATCTCGGGCCAGGG
GGAAGCCAGATTGGGCATAAAGAATCAATCAAGGATACCGCCCGTGTATTAGGCCGTATGTATGACGGCATTCAATATCG
TGGCTATGGGCAACGCGTGGTGGAAACACTCGCAGAATTTGCCGGCGTACCGGTCTGGAATGGCCTGACCGATGAGTTTC
ATCCAACCCAACTCCTGGCTGATTTGCTGACTATGCGGGAACACCTGCCCAATAAATCGCTGAATAAAATGACGTTGGCG
TACCTCGGTGATACACGTAATAACATGGGGAACAGCCTGTTAGAAGCGGCCGCACTGGTAGGAATGGATTTACGCCTAGT
CGCACCGAAAGCCTGTTGGCCAGAGGAAGCCTTCGTTATCAGTTGCCAGGCACTGGCACAGAAAACGGGGGGCAAAATCA
CCCTGACAGAAGATATTGCCGAGGGAGTGAACGGCGCTGATTTTCTTTATACCGATGTCTGGGTCTCGATGGGGGAACCC
AAAGAGGTCTGGCAGGAACGCATCAACTTACTCAAACCTTATCAGGTCAATATGCGTGTACTGACGCTGACCGGTAACCC
TCAGGTAAAATTTCTGCACTGCCTCCCCGCCTTCCACGATGACCAAACCACCATCGGTAAGCAGATGGCCGAACAATATG
ATTTACCCGGCGGCATGGAAGTGACTGAAGAGGTGTTTGAATCAGCTCATAGCATTGTATTTGATCAGGCAGAAAACCGC
CTGCATACCATCAAAGCCGTGATGGTCGCCACGATGAGCAAAATATAA

Upstream 100 bases:

>100_bases
ATACCTATAAATTGAATTTAAATTCATATTGAAATTCAATTTACCCCCAAATAATTGGTGTTGTAAGCATCAAGGATGAA
GGGCACATGGAGACGAACAG

Downstream 100 bases:

>100_bases
AGGCAGCCGATGACAATAATAAGGGCTGATCCGTTATCTATATCGGCCCTTTACCTATAAAATTCAGACGACGTGCAGCG
CGCAGCCAACGGAGCGTACA

Product: ornithine carbamoyltransferase subunit I

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPG
GSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEFAGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLA
YLGDTRNNMGNSLLEAAALVGMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEP
KEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGMEVTEEVFESAHSIVFDQAENR
LHTIKAVMVATMSKI

Sequences:

>Translated_335_residues
MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPG
GSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEFAGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLA
YLGDTRNNMGNSLLEAAALVGMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEP
KEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGMEVTEEVFESAHSIVFDQAENR
LHTIKAVMVATMSKI
>Mature_335_residues
MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPG
GSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEFAGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLA
YLGDTRNNMGNSLLEAAALVGMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEP
KEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGMEVTEEVFESAHSIVFDQAENR
LHTIKAVMVATMSKI

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=37.9518072289157, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI18105007, Length=338, Percent_Identity=26.0355029585799, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=79.6407185628742, Blast_Score=573, Evalue=1e-165,
Organism=Escherichia coli, GI1786469, Length=334, Percent_Identity=78.1437125748503, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI48994908, Length=380, Percent_Identity=23.9473684210526, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367364, Length=340, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204318, Length=224, Percent_Identity=31.25, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=329, Percent_Identity=32.5227963525836, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322331, Length=167, Percent_Identity=31.1377245508982, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642586, Length=328, Percent_Identity=25.9146341463415, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37479; Mature: 37479

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCCE
CSFEVAAYDQGARVTYLGPGGSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEF
EEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHH
AGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLAYLGDTRNNMGNSLLEAAALV
HCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHH
GMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEP
CCCEEEECCCCCCCCCHHEEEHHHHHHHCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCCH
KEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGME
HHHHHHHHHCCCCEEECEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCH
VTEEVFESAHSIVFDQAENRLHTIKAVMVATMSKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTR
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCCE
CSFEVAAYDQGARVTYLGPGGSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEF
EEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHH
AGVPVWNGLTDEFHPTQLLADLLTMREHLPNKSLNKMTLAYLGDTRNNMGNSLLEAAALV
HCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHH
GMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEP
CCCEEEECCCCCCCCCHHEEEHHHHHHHCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCCH
KEVWQERINLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGME
HHHHHHHHHCCCCEEECEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCH
VTEEVFESAHSIVFDQAENRLHTIKAVMVATMSKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA