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The map label for this gene is valS

Identifier: 218930459

GI number: 218930459

Start: 3848237

End: 3851134

Strand: Direct

Name: valS

Synonym: YPO3443

Alternate gene names: 218930459

Gene position: 3848237-3851134 (Clockwise)

Preceding gene: 218930458

Following gene: 218930460

Centisome position: 82.69

GC content: 51.97

Gene sequence:

>2898_bases
ATGGAAAATACACCTTCTCATATCAACAAAACTGAGCCGTCCCTCGATAAAACATACAGCCCGCAGGAAATTGAGCAGCC
GCTGTATGAACATTGGGAGAAACAGGGTTATTTCAAACCAAACGGCGATACCAGCAAAGAAAGCTACTGCATCATGATCC
CGCCGCCGAACGTGACCGGCAGCCTGCATATGGGTCATGCATTCCAGCAGACAATCATGGATACCTTGATTCGCTATCAG
CGTATGCAGGGGAAAAATACCCTCTGGCAGGCAGGTACTGATCATGCAGGTATCGCGACCCAGATGGTTGTGGAACGCAA
GATTGCCGCCGAAGAAGGCAAGACCCGCCACGATTACGGCCGTGATGCGTTTATCGATAAAATCTGGGAGTGGAAAGGCG
AATCCGGCGGCACCATTACTCGCCAAATGCGTCGTTTGGGTAACTCCGTGGACTGGGAACGTGAACGTTTCACTATGGAT
GAAGGCTTGTCCAACGCAGTTAAAGAAGTGTTCGTGCGCCTTCATAAAGAAGATCTGATTTACCGTGGCAAGCGCCTGGT
GAACTGGGATCCGAAACTGCGTACTGCCATTTCTGATCTGGAAGTAGAAAACCGCGAATCCAAAGGTTCCATGTGGCACC
TGCGTTATCCGCTGGCCGATGGTGCCAAGACTGCGGAAGGCAAAGATTATCTGGTGGTGGCAACCACCCGTCCAGAAACC
GTTCTGGGTGATACTGGTGTCGCGGTTAACCCGGAAGATCCACGTTATAAAGATCTGATCGGCAAAGAAGTGATCCTGCC
GCTGGTTGGCCGCCGTATTCCGATCCTCGGTGACGAACACGCCGATATGGAGAAGGGCACCGGTTGTGTGAAAATCACCC
CAGCCCACGACTTTAATGACTATGAAGTCGGTAAGCGCCATGCCCTGCCAATGATCAACATTCTGACCTTCGACGGGGAT
ATCCGCTCAGAAGCCGAGGTATTTGATACCCACGGTGAAGCAACTGATGCATTCAGTAACGCTATTCCTGCGCAGTTCCA
AGGGCTAGAACGTTTTGCTGCCCGTAAAGCGGTGGTCGCGGAATTCGAGAAACTCGGTCTGTTGGAAGAGGTTAAACCTC
ATGACCTGACAGTACCTTATGGCGACCGTGGCGGCGTGGTTATCGAACCCATGCTGACCGATCAATGGTACGTGCACACC
GCCCCGCTGGCCAAAGTCGCGATTGAAGCCGTAGAGAACGGCGAGATCCAGTTCGTCCCTAAACAGTACGAAAACATGTA
TTACTCATGGATGCGCGATATCCAGGACTGGTGTATCTCACGTCAATTGTGGTGGGGCCACCGTATTCCGGCCTGGTATG
ACGAGCAGGGTAATGTGTATGTTGGCCGCGACGAAGCCGAAGTGCGTCGCGACAATAATCTGGGCGCAGAGGTTGCTTTG
CGTCAGGACGAAGATGTGTTGGACACCTGGTTCTCATCCGGCCTGTGGACATTCTCTACACTGGGCTGGCCTGAACAAAC
CGACGCACTGAAAACCTTCCATCCGACCAGCGTGGTCGTCAGTGGTTTTGATATTATTTTCTTCTGGATTGCCCGCATGA
TCATGCTGACCATGCACTTTATGAAAGATGAAAATGGTAAACCACAGGTGCCGTTCAAAACGGTCTACATGACCGGTCTG
ATCCGTGATGACGAAGGGCAGAAAATGTCCAAGTCCAAAGGTAACGTGATCGATCCACTGGATATGGTTGACGGTATCTC
TTTGGAAGCGTTGCTGGAAAAACGTACCGGCAATATGATGCAGCCACAGTTGGCGGAGAAAATTCGCAAGCGCACTGAAA
AGCAGTTCCCGAACGGTATCGAGCCGCACGGCACTGATGCACTGCGCTTCACGTTGGCGGCACTGGCCTCAACTGGCCGT
GATATCAACTGGGATATGAAACGCCTGGAAGGGTATCGCAACTTCTGTAATAAGCTGTGGAATGCCAGCCGTTTCGTGCT
GATGAATACCGAAGGGCAGGATTGTGGGCAGAACGGTGGCGAAATGGTGTTATCACTGGCTGACCGCTGGATTTTGGCGG
AATTCAACCAGACCATCAAAGCCTACCGTGAAGCGATGGACACCTACCGCTTCGATCTGGCGGCCGGTATTCTGTATGAA
TTCACCTGGAACCAGTTCTGTGACTGGTATCTGGAACTGACCAAGCCGGTGATGAACAGTGGCTCTGAAGCTGAACTGCG
AGGCACTCGCCACACGCTGATTCAGGTGCTGGAAGCCTTGCTACGCTTGGCGCACCCCATCATTCCTTACATCACTGAAA
CTATCTGGCAGCGGGTGAAAAACCTGAAAGGCATTACTGCAGACACGATTATGTTGCAGCCTTTCCCAGAATATGATGCC
AGCCAAGTCGATGAACAAGCACTCAGTGATTTAGAGTGGATTAAGCAAACCATTATCGCGGTGCGTAATATCCGGGCGGA
AATGAACATTGCACCGGGTAAACCACTTGAGGTCATGCTGCGGGGTGCCAACGCACAAGCACAGCGTCGGGTGCTGGAAA
ACCAGAGTTTTATCCAGTCATTGGCGCGCTTGTCCTCTCTCACCTTGCTAGCTGAAGGTGATAAAGGCCCAGTATCGGTC
ACTAAATTGGTTGAAGGTGCTGAAGTGCTGATCCCAATGGCAGGCCTGATCGATAAAGCCACCGAGTTGGATCGTCTGGC
GAAGGAAGTGGCGAAACTGGATGCTGAAATTGAGCGCATCGAAGGCAAACTGGGTAACGAAGGTTTTGTGGCGCGGGCGC
CAGAAGCGGTAGTTGCCAAAGAGCGTGAAAGACTGGCCGCTTGTGCTGAAGCCAAACAGAAGTTAATTGAGCAGCAGGCA
ACTATCGCTGCACTATAA

Upstream 100 bases:

>100_bases
AAATTTGAAACAGTTGGCGCGCGACCGATATAAATCTTATCGCAGCGTCGGCTTCCACTTGACCACGGCAACGCCGCCAA
CTAATTGAAATAAAAAGAAA

Downstream 100 bases:

>100_bases
TTAATCAAACTATCAGTCAGTCGTCACCAGGGGCCATGATAATTATTCACTATCATGGCCCCTGCTTTTTACCATTGCAC
CCTGGCACCATTCGATGGTA

Product: valyl-tRNA synthetase

Products: NA

Alternate protein names: Valine--tRNA ligase; ValRS

Number of amino acids: Translated: 965; Mature: 965

Protein sequence:

>965_residues
MENTPSHINKTEPSLDKTYSPQEIEQPLYEHWEKQGYFKPNGDTSKESYCIMIPPPNVTGSLHMGHAFQQTIMDTLIRYQ
RMQGKNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYGRDAFIDKIWEWKGESGGTITRQMRRLGNSVDWERERFTMD
EGLSNAVKEVFVRLHKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHLRYPLADGAKTAEGKDYLVVATTRPET
VLGDTGVAVNPEDPRYKDLIGKEVILPLVGRRIPILGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGD
IRSEAEVFDTHGEATDAFSNAIPAQFQGLERFAARKAVVAEFEKLGLLEEVKPHDLTVPYGDRGGVVIEPMLTDQWYVHT
APLAKVAIEAVENGEIQFVPKQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVGRDEAEVRRDNNLGAEVAL
RQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTSVVVSGFDIIFFWIARMIMLTMHFMKDENGKPQVPFKTVYMTGL
IRDDEGQKMSKSKGNVIDPLDMVDGISLEALLEKRTGNMMQPQLAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGR
DINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGQNGGEMVLSLADRWILAEFNQTIKAYREAMDTYRFDLAAGILYE
FTWNQFCDWYLELTKPVMNSGSEAELRGTRHTLIQVLEALLRLAHPIIPYITETIWQRVKNLKGITADTIMLQPFPEYDA
SQVDEQALSDLEWIKQTIIAVRNIRAEMNIAPGKPLEVMLRGANAQAQRRVLENQSFIQSLARLSSLTLLAEGDKGPVSV
TKLVEGAEVLIPMAGLIDKATELDRLAKEVAKLDAEIERIEGKLGNEGFVARAPEAVVAKERERLAACAEAKQKLIEQQA
TIAAL

Sequences:

>Translated_965_residues
MENTPSHINKTEPSLDKTYSPQEIEQPLYEHWEKQGYFKPNGDTSKESYCIMIPPPNVTGSLHMGHAFQQTIMDTLIRYQ
RMQGKNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYGRDAFIDKIWEWKGESGGTITRQMRRLGNSVDWERERFTMD
EGLSNAVKEVFVRLHKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHLRYPLADGAKTAEGKDYLVVATTRPET
VLGDTGVAVNPEDPRYKDLIGKEVILPLVGRRIPILGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGD
IRSEAEVFDTHGEATDAFSNAIPAQFQGLERFAARKAVVAEFEKLGLLEEVKPHDLTVPYGDRGGVVIEPMLTDQWYVHT
APLAKVAIEAVENGEIQFVPKQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVGRDEAEVRRDNNLGAEVAL
RQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTSVVVSGFDIIFFWIARMIMLTMHFMKDENGKPQVPFKTVYMTGL
IRDDEGQKMSKSKGNVIDPLDMVDGISLEALLEKRTGNMMQPQLAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGR
DINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGQNGGEMVLSLADRWILAEFNQTIKAYREAMDTYRFDLAAGILYE
FTWNQFCDWYLELTKPVMNSGSEAELRGTRHTLIQVLEALLRLAHPIIPYITETIWQRVKNLKGITADTIMLQPFPEYDA
SQVDEQALSDLEWIKQTIIAVRNIRAEMNIAPGKPLEVMLRGANAQAQRRVLENQSFIQSLARLSSLTLLAEGDKGPVSV
TKLVEGAEVLIPMAGLIDKATELDRLAKEVAKLDAEIERIEGKLGNEGFVARAPEAVVAKERERLAACAEAKQKLIEQQA
TIAAL
>Mature_965_residues
MENTPSHINKTEPSLDKTYSPQEIEQPLYEHWEKQGYFKPNGDTSKESYCIMIPPPNVTGSLHMGHAFQQTIMDTLIRYQ
RMQGKNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYGRDAFIDKIWEWKGESGGTITRQMRRLGNSVDWERERFTMD
EGLSNAVKEVFVRLHKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHLRYPLADGAKTAEGKDYLVVATTRPET
VLGDTGVAVNPEDPRYKDLIGKEVILPLVGRRIPILGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGD
IRSEAEVFDTHGEATDAFSNAIPAQFQGLERFAARKAVVAEFEKLGLLEEVKPHDLTVPYGDRGGVVIEPMLTDQWYVHT
APLAKVAIEAVENGEIQFVPKQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVGRDEAEVRRDNNLGAEVAL
RQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTSVVVSGFDIIFFWIARMIMLTMHFMKDENGKPQVPFKTVYMTGL
IRDDEGQKMSKSKGNVIDPLDMVDGISLEALLEKRTGNMMQPQLAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGR
DINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGQNGGEMVLSLADRWILAEFNQTIKAYREAMDTYRFDLAAGILYE
FTWNQFCDWYLELTKPVMNSGSEAELRGTRHTLIQVLEALLRLAHPIIPYITETIWQRVKNLKGITADTIMLQPFPEYDA
SQVDEQALSDLEWIKQTIIAVRNIRAEMNIAPGKPLEVMLRGANAQAQRRVLENQSFIQSLARLSSLTLLAEGDKGPVSV
TKLVEGAEVLIPMAGLIDKATELDRLAKEVAKLDAEIERIEGKLGNEGFVARAPEAVVAKERERLAACAEAKQKLIEQQA
TIAAL

Specific function: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val)

COG id: COG0525

COG function: function code J; Valyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5454158, Length=990, Percent_Identity=39.4949494949495, Blast_Score=712, Evalue=0.0,
Organism=Homo sapiens, GI268370297, Length=959, Percent_Identity=36.7049009384776, Blast_Score=604, Evalue=1e-172,
Organism=Homo sapiens, GI268370293, Length=959, Percent_Identity=36.7049009384776, Blast_Score=603, Evalue=1e-172,
Organism=Homo sapiens, GI268370295, Length=918, Percent_Identity=37.037037037037, Blast_Score=581, Evalue=1e-166,
Organism=Homo sapiens, GI46852147, Length=822, Percent_Identity=22.7493917274939, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI94721239, Length=954, Percent_Identity=21.6981132075472, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI94721241, Length=954, Percent_Identity=21.6981132075472, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI7661872, Length=192, Percent_Identity=26.0416666666667, Blast_Score=75, Evalue=4e-13,
Organism=Escherichia coli, GI1790708, Length=951, Percent_Identity=87.2765509989485, Blast_Score=1740, Evalue=0.0,
Organism=Escherichia coli, GI2367096, Length=865, Percent_Identity=22.3121387283237, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1786861, Length=434, Percent_Identity=26.7281105990783, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17510661, Length=1014, Percent_Identity=37.67258382643, Blast_Score=669, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72001587, Length=810, Percent_Identity=35.9259259259259, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17541896, Length=995, Percent_Identity=21.8090452261307, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6321531, Length=970, Percent_Identity=41.2371134020619, Blast_Score=695, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319395, Length=908, Percent_Identity=21.0352422907489, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17864482, Length=985, Percent_Identity=39.3908629441624, Blast_Score=707, Evalue=0.0,
Organism=Drosophila melanogaster, GI24653289, Length=985, Percent_Identity=39.3908629441624, Blast_Score=707, Evalue=0.0,
Organism=Drosophila melanogaster, GI21355675, Length=805, Percent_Identity=38.3850931677019, Blast_Score=537, Evalue=1e-152,
Organism=Drosophila melanogaster, GI281366294, Length=846, Percent_Identity=21.9858156028369, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574730, Length=952, Percent_Identity=21.1134453781513, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24668547, Length=952, Percent_Identity=21.1134453781513, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24668543, Length=952, Percent_Identity=21.1134453781513, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21355409, Length=193, Percent_Identity=28.4974093264249, Blast_Score=91, Evalue=4e-18,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYV_YERPE (Q8ZBH1)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AE0418
- RefSeq:   NP_668079.1
- RefSeq:   NP_992032.1
- RefSeq:   YP_002348334.1
- ProteinModelPortal:   Q8ZBH1
- IntAct:   Q8ZBH1
- GeneID:   1145690
- GeneID:   1176261
- GeneID:   2763826
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO3443
- KEGG:   ypk:y0743
- KEGG:   ypm:YP_0641
- HOGENOM:   HBG577712
- OMA:   KAGRPER
- ProtClustDB:   PRK05729
- BioCyc:   YPES187410:Y0743-MONOMER
- BioCyc:   YPES214092:YPO3443-MONOMER
- BRENDA:   6.1.1.9
- GO:   GO:0005737
- HAMAP:   MF_02004
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR014729
- InterPro:   IPR010978
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR019499
- InterPro:   IPR009008
- InterPro:   IPR002303
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF5
- PRINTS:   PR00986
- TIGRFAMs:   TIGR00422

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; PF10458 Val_tRNA-synt_C; SSF46589 tRNA_binding_arm; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.9

Molecular weight: Translated: 109567; Mature: 109567

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 571-571

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTPSHINKTEPSLDKTYSPQEIEQPLYEHWEKQGYFKPNGDTSKESYCIMIPPPNVTG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCC
SLHMGHAFQQTIMDTLIRYQRMQGKNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYG
CEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RDAFIDKIWEWKGESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLHKEDLI
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRGKRLVNWDPKLRTAISDLEVENRESKGSMWHLRYPLADGAKTAEGKDYLVVATTRPET
HCCCEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCE
VLGDTGVAVNPEDPRYKDLIGKEVILPLVGRRIPILGDEHADMEKGTGCVKITPAHDFND
EECCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEEECCCCCCC
YEVGKRHALPMINILTFDGDIRSEAEVFDTHGEATDAFSNAIPAQFQGLERFAARKAVVA
CCCCCHHCCCEEEEEEECCCCCCCHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
EFEKLGLLEEVKPHDLTVPYGDRGGVVIEPMLTDQWYVHTAPLAKVAIEAVENGEIQFVP
HHHHCCCHHHCCCCCEECCCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHCCCCEEECC
KQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVGRDEAEVRRDNNLGAEVAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCHHHHHHCCCCCCEEEE
RQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTSVVVSGFDIIFFWIARMIMLTMHF
CCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKDENGKPQVPFKTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLEALLEKRTGNMM
HHCCCCCCCCCEEEEEEEEEEECCCCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCCCC
QPQLAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLW
CHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
NASRFVLMNTEGQDCGQNGGEMVLSLADRWILAEFNQTIKAYREAMDTYRFDLAAGILYE
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTWNQFCDWYLELTKPVMNSGSEAELRGTRHTLIQVLEALLRLAHPIIPYITETIWQRVK
HHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLKGITADTIMLQPFPEYDASQVDEQALSDLEWIKQTIIAVRNIRAEMNIAPGKPLEVML
HCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
RGANAQAQRRVLENQSFIQSLARLSSLTLLAEGDKGPVSVTKLVEGAEVLIPMAGLIDKA
ECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHH
TELDRLAKEVAKLDAEIERIEGKLGNEGFVARAPEAVVAKERERLAACAEAKQKLIEQQA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIAAL
HHHCC
>Mature Secondary Structure
MENTPSHINKTEPSLDKTYSPQEIEQPLYEHWEKQGYFKPNGDTSKESYCIMIPPPNVTG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCC
SLHMGHAFQQTIMDTLIRYQRMQGKNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYG
CEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RDAFIDKIWEWKGESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLHKEDLI
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRGKRLVNWDPKLRTAISDLEVENRESKGSMWHLRYPLADGAKTAEGKDYLVVATTRPET
HCCCEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCE
VLGDTGVAVNPEDPRYKDLIGKEVILPLVGRRIPILGDEHADMEKGTGCVKITPAHDFND
EECCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCEEEEECCCCCCC
YEVGKRHALPMINILTFDGDIRSEAEVFDTHGEATDAFSNAIPAQFQGLERFAARKAVVA
CCCCCHHCCCEEEEEEECCCCCCCHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
EFEKLGLLEEVKPHDLTVPYGDRGGVVIEPMLTDQWYVHTAPLAKVAIEAVENGEIQFVP
HHHHCCCHHHCCCCCEECCCCCCCCEEEEEEECCCEEEECCHHHHHHHHHHCCCCEEECC
KQYENMYYSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVGRDEAEVRRDNNLGAEVAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCHHHHHHCCCCCCEEEE
RQDEDVLDTWFSSGLWTFSTLGWPEQTDALKTFHPTSVVVSGFDIIFFWIARMIMLTMHF
CCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKDENGKPQVPFKTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLEALLEKRTGNMM
HHCCCCCCCCCEEEEEEEEEEECCCCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCCCC
QPQLAEKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLW
CHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
NASRFVLMNTEGQDCGQNGGEMVLSLADRWILAEFNQTIKAYREAMDTYRFDLAAGILYE
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTWNQFCDWYLELTKPVMNSGSEAELRGTRHTLIQVLEALLRLAHPIIPYITETIWQRVK
HHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLKGITADTIMLQPFPEYDASQVDEQALSDLEWIKQTIIAVRNIRAEMNIAPGKPLEVML
HCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
RGANAQAQRRVLENQSFIQSLARLSSLTLLAEGDKGPVSVTKLVEGAEVLIPMAGLIDKA
ECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHH
TELDRLAKEVAKLDAEIERIEGKLGNEGFVARAPEAVVAKERERLAACAEAKQKLIEQQA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIAAL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430