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The map label for this gene is hofC [H]

Identifier: 218930444

GI number: 218930444

Start: 3831513

End: 3832712

Strand: Direct

Name: hofC [H]

Synonym: YPO3427

Alternate gene names: 218930444

Gene position: 3831513-3832712 (Clockwise)

Preceding gene: 218930443

Following gene: 218930446

Centisome position: 82.33

GC content: 45.5

Gene sequence:

>1200_bases
TTGAGCCGCCATCGTTTATTCAATTGGACAGCTCTCAACAAAACAGGGGAGCTACAGACGGGCATGCTACTGGCAACTGA
GAGAAACAGTGTCTATGAACATATCATCCAACATGGCTTACAGCCCCTAGGCGTGAAAGGGGGAAGGCGGTTATCTGCAC
GCTACTGGCAAGGGGAACGGTTGGTGGCAATGACCCGCCAATTAGCGACTTTATTGCAAGCGGGTTTACCGTTGGTCAAC
AGTTTACAATTATTGGCAAAAGAGGCAGATGACTCAGCATGGCGTTGCCTATTAGATGAGATAAGTCAGCAAGTTGCACA
AGGCCAGTCACTCTCGGAAGTGATGGAACAGTATCCACACGTATTCCCCCGACTGTATCCTCCAGTGGTTGCCGTCGGGG
AGCTTACGGGTAATCTTGAGCAATGTTGTACTCAATTAGTACACCATCAGGAACGGCAGCAAAATTTACACAAAAAAGTC
ATAAAAGCGCTGAAATACCCCGTTGTGGTCTGCATCGTCGCATTGGTAGTCAGTGTCATTATGTTAGTCATGGTGTTACC
CGAATTTGCACAAATATATCAATCGTTTGATACCCCCCTGCCGGGGCTAACTGCAAGCTTACTGTGGCTATCAACTTTTC
TCACTTTTTATGGCCCCTATCTGGCGCTGATAATAGCAATAGTGTGTATTGGGTATTTCTATACATTACGAAAAAAATCT
CGCTGGCAGCAATGGGAACAGACCATTCTATTAAGCATTCCCTTAGTCTCAACATTAATCCGTGGTAGCTGCCTCAGCCA
AATTTTTCAAACGTTAGCTATCACACAACAAGCCGGGCTACCCCTGTCAGCCGGGTTAGATGCAGCGGCTCGATCCATTC
ACAACTACAATTATCAGCAAGCCTTAAGGTGTATTCAAAAACAAATTAGCCAAGGTATACCGCTGTATACCACTCTTAAT
CAGCACCCTTTATTTCCTGCCATTTGTCAGCAGCTCATTAGGGTTGGTGAAGAATCAGGCTCACAGGATGTGTTGCTGGA
AAAGTTAGCCTGTTGGCATCAGCAACAAACTCAGAATTTGGCAGATAACGTCACTCAAATGCTAGAGCCACTTCTTATGC
TGATTATTGGCAGTATTGTCGGCGTACTGGTGATCGCCATGTATTTACCCATATTCCAGTTAGGTGATGTTATTGGATAA

Upstream 100 bases:

>100_bases
CCTTACTCTGCTCAGGTTTAGCTTTAATCGAAAAAGGCATCACTACCCTTAGTGAAATTAATCGTGTTGTGGGCTTCGTA
GCAGAAACAGAGGTCACCTC

Downstream 100 bases:

>100_bases
CCTCATTATGGACCTAGTGGATGGTAAACTGGGCATAGTGGAGTGCATGGCATGCCATGGCGGGATGTAATGGCACGATC
AGGTGCAAGACCAGAGAGGC

Product: type IV pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSRHRLFNWTALNKTGELQTGMLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGERLVAMTRQLATLLQAGLPLVN
SLQLLAKEADDSAWRCLLDEISQQVAQGQSLSEVMEQYPHVFPRLYPPVVAVGELTGNLEQCCTQLVHHQERQQNLHKKV
IKALKYPVVVCIVALVVSVIMLVMVLPEFAQIYQSFDTPLPGLTASLLWLSTFLTFYGPYLALIIAIVCIGYFYTLRKKS
RWQQWEQTILLSIPLVSTLIRGSCLSQIFQTLAITQQAGLPLSAGLDAAARSIHNYNYQQALRCIQKQISQGIPLYTTLN
QHPLFPAICQQLIRVGEESGSQDVLLEKLACWHQQQTQNLADNVTQMLEPLLMLIIGSIVGVLVIAMYLPIFQLGDVIG

Sequences:

>Translated_399_residues
MSRHRLFNWTALNKTGELQTGMLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGERLVAMTRQLATLLQAGLPLVN
SLQLLAKEADDSAWRCLLDEISQQVAQGQSLSEVMEQYPHVFPRLYPPVVAVGELTGNLEQCCTQLVHHQERQQNLHKKV
IKALKYPVVVCIVALVVSVIMLVMVLPEFAQIYQSFDTPLPGLTASLLWLSTFLTFYGPYLALIIAIVCIGYFYTLRKKS
RWQQWEQTILLSIPLVSTLIRGSCLSQIFQTLAITQQAGLPLSAGLDAAARSIHNYNYQQALRCIQKQISQGIPLYTTLN
QHPLFPAICQQLIRVGEESGSQDVLLEKLACWHQQQTQNLADNVTQMLEPLLMLIIGSIVGVLVIAMYLPIFQLGDVIG
>Mature_398_residues
SRHRLFNWTALNKTGELQTGMLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGERLVAMTRQLATLLQAGLPLVNS
LQLLAKEADDSAWRCLLDEISQQVAQGQSLSEVMEQYPHVFPRLYPPVVAVGELTGNLEQCCTQLVHHQERQQNLHKKVI
KALKYPVVVCIVALVVSVIMLVMVLPEFAQIYQSFDTPLPGLTASLLWLSTFLTFYGPYLALIIAIVCIGYFYTLRKKSR
WQQWEQTILLSIPLVSTLIRGSCLSQIFQTLAITQQAGLPLSAGLDAAARSIHNYNYQQALRCIQKQISQGIPLYTTLNQ
HPLFPAICQQLIRVGEESGSQDVLLEKLACWHQQQTQNLADNVTQMLEPLLMLIIGSIVGVLVIAMYLPIFQLGDVIG

Specific function: Unknown

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=398, Percent_Identity=39.1959798994975, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789724, Length=398, Percent_Identity=27.1356783919598, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44753; Mature: 44622

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRHRLFNWTALNKTGELQTGMLLATERNSVYEHIIQHGLQPLGVKGGRRLSARYWQGER
CCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503; 2904262 [H]