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The map label for this gene is surE [H]

Identifier: 218930376

GI number: 218930376

Start: 3747003

End: 3747767

Strand: Reverse

Name: surE [H]

Synonym: YPO3358

Alternate gene names: 218930376

Gene position: 3747767-3747003 (Counterclockwise)

Preceding gene: 218930377

Following gene: 218930375

Centisome position: 80.53

GC content: 50.72

Gene sequence:

>765_bases
ATGATACGGATATTATTGAGTAACGATGATGGTATTTCTGCGCCAGGGATCCAGACGCTGGCCAGTGCATTGCGGGGATT
TGCTCAGGTGCAAATTGTGGCACCCGATCGTAACCGTAGTGGCGCTTCCAATGCATTGACTCTGGATAGTGCATTGCGGA
TCACTACCTTATCTAATGGTGATATTGCGGTGCAGCAAGGGACCCCCACCGATTGCGTCTATCTGGGTGTGAATGCGCTG
ATGCGCCCACGGCCTGACATCGTTGTCTCTGGTATTAATGCTGGCCCTAATTTAGGGGATGATGTTATCTATTCGGGTAC
CGTAGCAGCGGCGATGGAAGGGCGTCATTTGGGATACCCAGCCTTGGCTGTCTCGCTCAACGGTCATCAGCATTACGATA
CGGCGGCGGCAGTGACTTGCCGTTTATTACGTGCGTTACAGCGCAAACCACTGCGTACCGGCAAGATCCTCAATATAAAT
GTTCCTGATTTGCCTTTAGCGGAAATTAAAGGGATTCGGGTGACGCGTTGTGGTAGCCGCCATCCGGCAGAGCAGGTATT
TTGTCAGCAAGATCCCAGAGGGCAAGATCTTTATTGGATCGGGCCGCCGGGTGAAAAGTATGATGCAGGGCCAGATACTG
ACTTTGCGGCGGTTGAACAAGGTTATGTATCAATAACGCCGCTTCAAGTCGATTTAACGGCTTATATGGCACAAGAAGTG
GTTGAAAGTTGGTTAGCCAATACTGAGGTTGACGGGGAATGGTAA

Upstream 100 bases:

>100_bases
AACTGGTGGGATGATGTCACTCTTGAGCTGAGTTTCTGGCTCCCTGCGGGGAGCTTTGCGACCAGTGTGGTGAGGGAAAT
AATGAACCAGGATCGGGCTG

Downstream 100 bases:

>100_bases
ATAAACGCATGCAAACATTGTTGATGCAGTTACGTCAGCAAGGTATTCACGATGAACGCCTGTTACAGGCGATCGAAGCG
GTACCGCGTGAGCGTTTTGT

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: 5'/3'-nucleotidase; Nucleoside monophosphate phosphohydrolase; Exopolyphosphatase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MIRILLSNDDGISAPGIQTLASALRGFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNAL
MRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNIN
VPDLPLAEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYMAQEV
VESWLANTEVDGEW

Sequences:

>Translated_254_residues
MIRILLSNDDGISAPGIQTLASALRGFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNAL
MRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNIN
VPDLPLAEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYMAQEV
VESWLANTEVDGEW
>Mature_254_residues
MIRILLSNDDGISAPGIQTLASALRGFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNAL
MRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNIN
VPDLPLAEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYMAQEV
VESWLANTEVDGEW

Specific function: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'- monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase acti

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1789101, Length=253, Percent_Identity=80.2371541501976, Blast_Score=419, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002828 [H]

Pfam domain/function: PF01975 SurE [H]

EC number: =3.1.3.5; =3.1.3.6; =3.6.1.11 [H]

Molecular weight: Translated: 27231; Mature: 27231

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRILLSNDDGISAPGIQTLASALRGFAQVQIVAPDRNRSGASNALTLDSALRITTLSNG
CEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCEEEEEEECCC
DIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYP
CEEEECCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCC
ALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNINVPDLPLAEIKGIRVTRCGSR
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCEEEEECCCC
HPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYMAQEV
CCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEEEHHHHHHHHHH
VESWLANTEVDGEW
HHHHHHCCCCCCCC
>Mature Secondary Structure
MIRILLSNDDGISAPGIQTLASALRGFAQVQIVAPDRNRSGASNALTLDSALRITTLSNG
CEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCEEEEEEECCC
DIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYP
CEEEECCCCCCEEEECHHHHCCCCCCEEEEECCCCCCCCCCEEECCEEEEEECCCCCCCC
ALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNINVPDLPLAEIKGIRVTRCGSR
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCEEEEECCCC
HPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYMAQEV
CCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEEEHHHHHHHHHH
VESWLANTEVDGEW
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA