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The map label for this gene is gmhA [H]

Identifier: 218930270

GI number: 218930270

Start: 3608676

End: 3609257

Strand: Reverse

Name: gmhA [H]

Synonym: YPO3243

Alternate gene names: 218930270

Gene position: 3609257-3608676 (Counterclockwise)

Preceding gene: 218930272

Following gene: 218930269

Centisome position: 77.56

GC content: 45.7

Gene sequence:

>582_bases
ATGTACCACGATTTAATCCGTAGTGAATTGAACGAAGCAGCAGACACGCTGGCAAATTTTCTGAAAGATGATAGCAATAT
TGATGCCATTCAACGGGCCGCGATATTGCTGGCTGACTCTTTCAAGGCGGGTGGCAAAGTATTGTCATGTGGTAATGGGG
GTTCCCATTGTGATGCCATGCATTTTGCCGAAGAGTTGACGGGGCGTTATCGTGAAAACCGCCCCGGTTATCCAGCCATT
GCAATTTCGGATGTCAGCCATCTGTCATGTGTCAGTAATGACTTTGGCTACGATTATGTTTTCTCTCGCTATGTTGAAGC
GGTGGACCGTGAGGGGGATGTGTTACTGGGCATTTCTACTTCAGGTAATTCTGGTAATATCATTAAGGCGATTGAGGCTG
CTCGTGCCAAAGGCATGAAAGTTATCACGCTAACGGGGAAAGATGGCGGTAAAATGGCCGGCTCTGCGGATATTGAAATC
CGTGTTCCTCATTTCGGTTATGCCGATCGTATTCAGGAAATTCATATCAAAGTCATTCACATCTTGATTCAGTTGATCGA
AAAAGAGATGGTAAAAGCCTGA

Upstream 100 bases:

>100_bases
CATGCTAATGCATCACAGTGCTTCTCGCTGTTTATGCTATCCGGTACACTGATTGAGGAAAAATATTGATGCTATAGGAC
ATATAAAGAGGCCTTCCTTT

Downstream 100 bases:

>100_bases
TGTGCTGGGGTGATCAACCGCGGTATTAATCAAGTTGATCACCTCAATCTTCTGTGAACATTCCGGTTACCTCATAAAGC
GCCAAAAGTCATGCCTGTTT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHLSCVSNDFGYDYVFSRYVEAVDREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA

Sequences:

>Translated_193_residues
MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHLSCVSNDFGYDYVFSRYVEAVDREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
>Mature_193_residues
MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHLSCVSNDFGYDYVFSRYVEAVDREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=192, Percent_Identity=90.625, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1789539, Length=167, Percent_Identity=44.9101796407186, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20987; Mature: 20987

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAM
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHH
HFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVDREGDVLLGIST
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEC
SGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIH
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
ILIQLIEKEMVKA
HHHHHHHHHHHCC
>Mature Secondary Structure
MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAM
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHH
HFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVDREGDVLLGIST
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEC
SGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIH
CCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
ILIQLIEKEMVKA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA