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The map label for this gene is aroH [H]

Identifier: 218929501

GI number: 218929501

Start: 2711967

End: 2713013

Strand: Direct

Name: aroH [H]

Synonym: YPO2411

Alternate gene names: 218929501

Gene position: 2711967-2713013 (Clockwise)

Preceding gene: 218929500

Following gene: 218929523

Centisome position: 58.28

GC content: 50.53

Gene sequence:

>1047_bases
ATGTACAAGATAGATGAACTGCGGACCGCTCGCATCGATAGCTTGATTACACCGCAGCAACTGGCTGAAAAGTTACCGAT
TTCTGAGGTTATTGCAGATAACGTGACGGCGTCACGTAAACGAATAGAGAAAATACTTATTGGTGAAGACCCACGTCTAC
TCGTGGTGATTGGCCCCTGCTCTATTCACGACCTTGATGCAGCCGTTGATTATGCCACCCGGCTCAAGGTGCTACGAGAA
CGCTATCAAGACCGGCTGGAAATCGTGATGCGCACCTATTTCGAGAAACCACGGACTGTAGTGGGTTGGAAGGGGCTGAT
TTCTGATCCGGCACTTGACGGCTCATGCCAGGTGAACTTGGGTATTGAACTGGCACGTAAGCTACTGTTAGCCGTGAATG
AACTCGGGCTGCCGACCGCTACCGAGTTCCTCAATATGGTAACAGGCCAATATATTGCCGACCTCATCAGTTGGGGGGCA
ATAGGCGCACGTACCACCGAAAGCCAGATCCACCGAGAGATGGCCTCGGCACTCTCCTGCCCCGTGGGTTTCAAAAATGG
TACAGATGGCAATGTGCGTATTGCTATTGATGCCATTCGCGCCGCACAAGCCAGCCATATGTTCCTTTCTCCGGATAAAA
CCGGCCAAATGACGATTTACCAAACCAGTGGTAACCCCTATGGGCATATTATTATGCGGGGTGGAAAGCAACCTAACTAT
GATGCCTCTGATATCGCAGCCGCCTGTGACAGCTTGCGGGAATTTGATTTGCCAGAACATCTGGTGGTAGATTTTAGCCA
CGGCAATTGCCAGAAGATGCATCGCCGCCAGTTGGATGTTGCCGAAAATATCGGGCTACAGATCCGTGCGGGTTCAACAG
CGATTGTCGGTGTTATGGCTGAGAGTTTCCTGATTGAGGGCACACAGAAGATTGTTGCCGGACAGCCCTTAACTTATGGG
CAATCCATCACTGACCCTTGCCTGAATTGGGATGATACTGAACAACTGTTAAGCCTATTGGCAGATGCAGTAGACAGCCG
GTTTTAA

Upstream 100 bases:

>100_bases
TACAGTGATGACGGTTGAATTCATGTGATTTTGGTTTATTGTGATCGCCATCACTTCCCGGTATTTCTGCCGCAGAGAAG
AACAGATTTAGAGAGTTTTC

Downstream 100 bases:

>100_bases
TTCATTCGCACGGGCTTTAATGAGTAAACCGTACATTAAATGAATACCTTCGGGATAGGGAAAAGTTAACGTTGTCGGGT
TAACTTTTTCTATCCCTATT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MYKIDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPCSIHDLDAAVDYATRLKVLRE
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNLGIELARKLLLAVNELGLPTATEFLNMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMAESFLIEGTQKIVAGQPLTYG
QSITDPCLNWDDTEQLLSLLADAVDSRF

Sequences:

>Translated_348_residues
MYKIDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPCSIHDLDAAVDYATRLKVLRE
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNLGIELARKLLLAVNELGLPTATEFLNMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMAESFLIEGTQKIVAGQPLTYG
QSITDPCLNWDDTEQLLSLLADAVDSRF
>Mature_348_residues
MYKIDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPCSIHDLDAAVDYATRLKVLRE
RYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNLGIELARKLLLAVNELGLPTATEFLNMVTGQYIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMAESFLIEGTQKIVAGQPLTYG
QSITDPCLNWDDTEQLLSLLADAVDSRF

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=80.1724137931034, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=58.3815028901734, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1788953, Length=326, Percent_Identity=52.4539877300613, Blast_Score=343, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6319726, Length=349, Percent_Identity=46.4183381088825, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=44.1926345609065, Blast_Score=292, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38310; Mature: 38310

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKIDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPC
CCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDLDAAVDYATRLKVLRERYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEE
GIELARKLLLAVNELGLPTATEFLNMVTGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
CCCCCCCCCCCEEEEEEEHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMA
CHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ESFLIEGTQKIVAGQPLTYGQSITDPCLNWDDTEQLLSLLADAVDSRF
HHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYKIDELRTARIDSLITPQQLAEKLPISEVIADNVTASRKRIEKILIGEDPRLLVVIGPC
CCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCC
SIHDLDAAVDYATRLKVLRERYQDRLEIVMRTYFEKPRTVVGWKGLISDPALDGSCQVNL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEE
GIELARKLLLAVNELGLPTATEFLNMVTGQYIADLISWGAIGARTTESQIHREMASALSC
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNVRIAIDAIRAAQASHMFLSPDKTGQMTIYQTSGNPYGHIIMRGGKQPNY
CCCCCCCCCCCEEEEEEEHHHHHCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
DASDIAAACDSLREFDLPEHLVVDFSHGNCQKMHRRQLDVAENIGLQIRAGSTAIVGVMA
CHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ESFLIEGTQKIVAGQPLTYGQSITDPCLNWDDTEQLLSLLADAVDSRF
HHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]