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The map label for this gene is pdxH [H]

Identifier: 218929461

GI number: 218929461

Start: 2663279

End: 2663932

Strand: Reverse

Name: pdxH [H]

Synonym: YPO2370

Alternate gene names: 218929461

Gene position: 2663932-2663279 (Counterclockwise)

Preceding gene: 218929462

Following gene: 218929460

Centisome position: 57.24

GC content: 49.08

Gene sequence:

>654_bases
ATGACTGAGAATAATGAGTTTGATGTTGCAGACTTGCGTCGTGAGTATATTCGGGGTGGTCTGCGCCGCAGTGATTTAAC
TGAAAACCCTTTAGAATTATTCGAGCGCTGGTTAAAACAGGCATGTGAAGCTCGCTTGCCCGATCCGACCGCAATGTGTG
TGGCTACCGTTGATACCAATGGTCAGCCCTACCAGCGTATCGTGCTCTTGAAACATTATGATGATCAGGGCTTAGTGTTT
TACACCAATTTAGGTAGCCGCAAAGCACAACAATTGGCTGAGAACCCGCATATCAGCCTATTGTTTCCCTGGCATATGCT
GGATCGGCAAGTGATTTTCCTCGGCAAGGCGGAGCGCCTCTCCACATTGGAAGTCCTGAAGTATTTCCATTCCCGTCCGA
AAGACAGTCAAATTGGTGCTTGGGTTTCCCAGCAATCCTCACGTATTTCTGCTCGTGGTGTCCTGGAAAGCAAATTTCTT
GAGCTGAAACAAAAATTCCAGCAGGGTGACGTACCGCTGCCCAGTTTTTGGGGCGGGTTTCGCGTCAAATTCGATTCCGT
TGAGTTTTGGCAGGGGGGGGAACATCGCCTTCATGACCGTTTTATCTATCAACGGGAAGCCGACGCGTGGAAAATTGACC
GTTTAGCCCCTTAG

Upstream 100 bases:

>100_bases
GATCAAGTAATCTCGTCGTCGTAGGCTCTGGATGATTGTGATTCTGTGGCGGCGAGGGCAGAATGATAACCACAGCTTTC
CTGCGCGTTACAGAGTTTAT

Downstream 100 bases:

>100_bases
GACGATGAAATATTGTGGTTAAACTGTAACGGGCGCTTTATTCTATATGCCGATTAAACGCCTATGCTGATTAAAAGCCT
ATGCCGATTGAAAATATATG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVF
YTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFL
ELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP

Sequences:

>Translated_217_residues
MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVF
YTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFL
ELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
>Mature_216_residues
TENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVFY
TNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLE
LKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=203, Percent_Identity=41.3793103448276, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1787926, Length=218, Percent_Identity=78.4403669724771, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17553712, Length=227, Percent_Identity=35.6828193832599, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=39.2344497607655, Blast_Score=149, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45551845, Length=208, Percent_Identity=40.3846153846154, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24644901, Length=208, Percent_Identity=40.3846153846154, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24644903, Length=178, Percent_Identity=30.8988764044944, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 25383; Mature: 25252

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTN
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERL
CCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHCCCCEEEEECHHHHCCEEEEEECCHHH
STLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGF
HHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
RVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
EEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTN
CCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERL
CCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHCCCCEEEEECHHHHCCEEEEEECCHHH
STLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGF
HHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
RVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
EEEECCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA