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The map label for this gene is tonB [H]

Identifier: 218929291

GI number: 218929291

Start: 2469415

End: 2470173

Strand: Direct

Name: tonB [H]

Synonym: YPO2193

Alternate gene names: 218929291

Gene position: 2469415-2470173 (Clockwise)

Preceding gene: 218929289

Following gene: 218929296

Centisome position: 53.06

GC content: 49.28

Gene sequence:

>759_bases
ATGCAGCTAATAAAATTTTTCTCAGATCGACGGTTAACATGGTCACTCATTTTTTCAATAGGGTTGCACGGGAGTGTTGT
TGCGGCACTGCTGTACGTTTCCGTAGAGCAAATGAAAATTCAACCTGAAATTGAGGATACGCCTCTTGCTGTAACGATGG
TCAATATAGCGGAATTTGCTGCACCACAACCGGCTGCCGCCGCGCCAGAGCCAGTTCAAGAAACACCAGCCGTGCCCGAA
GAGACACCGCCTGTGCTTGAAGAGACACCACCGGAACCTGAAGAGCTGCCTGAGCCTGTTCCGGTGCCTGTTCCTGAACC
CGTGAAACCCAAGCCGAAGCCTGTTAAGAAAGAAGTTAAGAAGCCGGAAGTGAAGAAGACGCAAGCACCGCCGGATGACA
AACCGTTTAAATCTGATGAGGCCGCGCTGGTTGCGAACAATGCACCGGTAAAATCGGCACCAGTTGCCTCAACACCTGGC
TTATCAACATCCGCTGGGCCAAAGGCACTGAGTAAGGCTAAACCCTCTTATCCGGCTCGAGCATTGGCTTTAGGGATTGA
AGGGCAGGTTAAAGTACAGTACGACATTGATGAGAGTGGGCGAGTGACGAATGTCAGAGTGTTAGAAGCAACACCACGTA
ATACTTTTGAGCGTGAAGTGAAGCAGGTCATGCGTAAATGGCGTTTTGAAGCGGTCGCTGCTAAAAACTATGTGACTACC
ATTGTGTTCAAGCTCGATGGCAAAATGGAAATGAATTAA

Upstream 100 bases:

>100_bases
CGTCATTTAGCGCTAATTAACGAGAATGTTTGTCGTTCCTTATTGAACATGATTGCTATTTGCATTTAAACTTGGCTGCA
TCAGAGGACATTGAATCATT

Downstream 100 bases:

>100_bases
GAGCCTGTCCATAATTCTGTGTAACTGCCACCGTATTAAAGGTGATCGCTCAGGCGGTCACCGAACTCGATAATAAAACG
GCTCATCGCTAACCGCCAGT

Product: transport protein TonB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFAAPQPAAAAPEPVQETPAVPE
ETPPVLEETPPEPEELPEPVPVPVPEPVKPKPKPVKKEVKKPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPG
LSTSAGPKALSKAKPSYPARALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTT
IVFKLDGKMEMN

Sequences:

>Translated_252_residues
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFAAPQPAAAAPEPVQETPAVPE
ETPPVLEETPPEPEELPEPVPVPVPEPVKPKPKPVKKEVKKPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPG
LSTSAGPKALSKAKPSYPARALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTT
IVFKLDGKMEMN
>Mature_252_residues
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFAAPQPAAAAPEPVQETPAVPE
ETPPVLEETPPEPEELPEPVPVPVPEPVKPKPKPVKKEVKKPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPG
LSTSAGPKALSKAKPSYPARALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTT
IVFKLDGKMEMN

Specific function: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requirin

COG id: COG0810

COG function: function code M; Periplasmic protein TonB, links inner and outer membranes

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB family [H]

Homologues:

Organism=Escherichia coli, GI1787505, Length=126, Percent_Identity=46.031746031746, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003538
- InterPro:   IPR006260 [H]

Pfam domain/function: PF03544 TonB [H]

EC number: NA

Molecular weight: Translated: 27502; Mature: 27502

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFA
CCHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHHHC
APQPAAAAPEPVQETPAVPEETPPVLEETPPEPEELPEPVPVPVPEPVKPKPKPVKKEVK
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHC
KPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTSAGPKALSKAKPSYPAR
CCCCHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCE
ALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTT
EEEECCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
IVFKLDGKMEMN
EEEEECCCEECC
>Mature Secondary Structure
MQLIKFFSDRRLTWSLIFSIGLHGSVVAALLYVSVEQMKIQPEIEDTPLAVTMVNIAEFA
CCHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCEEEEEEHHHHHC
APQPAAAAPEPVQETPAVPEETPPVLEETPPEPEELPEPVPVPVPEPVKPKPKPVKKEVK
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHC
KPEVKKTQAPPDDKPFKSDEAALVANNAPVKSAPVASTPGLSTSAGPKALSKAKPSYPAR
CCCCHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCE
ALALGIEGQVKVQYDIDESGRVTNVRVLEATPRNTFEREVKQVMRKWRFEAVAAKNYVTT
EEEECCCCEEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
IVFKLDGKMEMN
EEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8384290 [H]