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The map label for this gene is selD

Identifier: 218929264

GI number: 218929264

Start: 2433966

End: 2435012

Strand: Direct

Name: selD

Synonym: YPO2164

Alternate gene names: 218929264

Gene position: 2433966-2435012 (Clockwise)

Preceding gene: 218929263

Following gene: 218929265

Centisome position: 52.3

GC content: 48.52

Gene sequence:

>1047_bases
ATGGCATCGCCAGCGATACGTCTTACTCAATACAGCCACGGAGCGGGCTGTGGTTGCAAGATTTCACCAAAAGTTTTGGA
TAAAATTTTGCATACTGAGCAACAAAAGTTTTTTGATCCCCGGTTGCTGGTGGGCAATGAAACGCGTGATGATGCAGCGG
TTTATGATATTGGTAACGGTGTTGGCATTATCAGCACGACTGATTTTTTTATGCCGATCGTTGATGATCCTTTTGATTTT
GGGCGTATTGCCGCCACAAACGCGATCAGCGATGTATATGCTATGGGCGGTAAACCCATAATGGCTATTGCTATTTTGGG
GTGGCCCATTGACAAACTGGCACCCGAAATCGCACAGCAAGTGATCGAGGGTGGGCGATATGTTTGCCAGCAAGCGGGGA
TTTCTTTGGCAGGCGGGCACTCTATTGATGCCCCTGAACCCATTTTGGGTTTGGCTGTTACCGGAATTGTCAGCACTGAA
CAGGTTAAGAAAAACAGTGCTGCAAAGCCAGGATGCAAACTGTTTTTGACCAAGCCATTGGGCATTGGCATCTTAACGAC
AGCCGAAAAGAAAAGTAAATTACGGCCAGAACATCGGGGATTGGCAACGGAAACCATGTGTCAGTTGAATAAGCCCGGCG
CTGATTTTGCGCATATTCCCGGTGTTACCGCCATGACCGATGTCACGGGGTTTGGTCTGTTGGGGCATTTGAGTGAAATT
TGTCAGGGTTCTGGTGTCCAGGCCATTCTGCATTACTCTGCGATCCCACGTTTACCTGCCGTTGAAGACTATATTGCTGA
AGGTTGTGTTCCAGGGGGGACTGGGCGTAATTTCGACAGTTATGGTCACCTGATCGGTAATATGTCTGATTTACAAAAAC
AATTACTTTGTGATCCTCAAACCTCTGGCGGATTACTGTTGGCGGTCTTACCTGATGCTGAAGCCGATGTACAGGCCATT
GCCGCTCAGCACGGAATGACCCTCAGCCCAATTGGTGAATTAACCTCGGCGGATAGTCGCCGGGCGCTGATTGAGATTGT
AGTGTGA

Upstream 100 bases:

>100_bases
CGTCTTAAGCGCTACCATAGGCAATCTGGGGATTATTTTATTGAATCAATCGACGACTTACTAAACTGCTTATCACCGAA
TGACCTAACGGGAGAGTTCT

Downstream 100 bases:

>100_bases
TGGATTGTAGTGTGATGGATTGTAGCGTGATGTTTTCTTTGACGTATTTATGCGGTGAATGATGCGACTGTTTATTGCCG
AAAAACCCAGTTTAGCGCGA

Product: selenophosphate synthetase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MASPAIRLTQYSHGAGCGCKISPKVLDKILHTEQQKFFDPRLLVGNETRDDAAVYDIGNGVGIISTTDFFMPIVDDPFDF
GRIAATNAISDVYAMGGKPIMAIAILGWPIDKLAPEIAQQVIEGGRYVCQQAGISLAGGHSIDAPEPILGLAVTGIVSTE
QVKKNSAAKPGCKLFLTKPLGIGILTTAEKKSKLRPEHRGLATETMCQLNKPGADFAHIPGVTAMTDVTGFGLLGHLSEI
CQGSGVQAILHYSAIPRLPAVEDYIAEGCVPGGTGRNFDSYGHLIGNMSDLQKQLLCDPQTSGGLLLAVLPDAEADVQAI
AAQHGMTLSPIGELTSADSRRALIEIVV

Sequences:

>Translated_348_residues
MASPAIRLTQYSHGAGCGCKISPKVLDKILHTEQQKFFDPRLLVGNETRDDAAVYDIGNGVGIISTTDFFMPIVDDPFDF
GRIAATNAISDVYAMGGKPIMAIAILGWPIDKLAPEIAQQVIEGGRYVCQQAGISLAGGHSIDAPEPILGLAVTGIVSTE
QVKKNSAAKPGCKLFLTKPLGIGILTTAEKKSKLRPEHRGLATETMCQLNKPGADFAHIPGVTAMTDVTGFGLLGHLSEI
CQGSGVQAILHYSAIPRLPAVEDYIAEGCVPGGTGRNFDSYGHLIGNMSDLQKQLLCDPQTSGGLLLAVLPDAEADVQAI
AAQHGMTLSPIGELTSADSRRALIEIVV
>Mature_347_residues
ASPAIRLTQYSHGAGCGCKISPKVLDKILHTEQQKFFDPRLLVGNETRDDAAVYDIGNGVGIISTTDFFMPIVDDPFDFG
RIAATNAISDVYAMGGKPIMAIAILGWPIDKLAPEIAQQVIEGGRYVCQQAGISLAGGHSIDAPEPILGLAVTGIVSTEQ
VKKNSAAKPGCKLFLTKPLGIGILTTAEKKSKLRPEHRGLATETMCQLNKPGADFAHIPGVTAMTDVTGFGLLGHLSEIC
QGSGVQAILHYSAIPRLPAVEDYIAEGCVPGGTGRNFDSYGHLIGNMSDLQKQLLCDPQTSGGLLLAVLPDAEADVQAIA
AQHGMTLSPIGELTSADSRRALIEIVV

Specific function: Synthesizes selenophosphate from selenide and ATP

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily

Homologues:

Organism=Homo sapiens, GI24797148, Length=344, Percent_Identity=30.2325581395349, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI15011844, Length=361, Percent_Identity=27.9778393351801, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788062, Length=346, Percent_Identity=75.4335260115607, Blast_Score=547, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17543426, Length=367, Percent_Identity=29.4277929155313, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24653602, Length=380, Percent_Identity=28.6842105263158, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24653604, Length=380, Percent_Identity=28.6842105263158, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELD_YERPE (Q8ZEK1)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AH0263
- RefSeq:   NP_669468.1
- RefSeq:   NP_993304.1
- RefSeq:   YP_002347139.1
- ProteinModelPortal:   Q8ZEK1
- SMR:   Q8ZEK1
- IntAct:   Q8ZEK1
- GeneID:   1147104
- GeneID:   1174998
- GeneID:   2766369
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2164
- KEGG:   ypk:y2157
- KEGG:   ypm:YP_1964
- HOGENOM:   HBG383791
- OMA:   HKLARAS
- ProtClustDB:   PRK00943
- BioCyc:   YPES187410:Y2157-MONOMER
- BioCyc:   YPES214092:YPO2164-MONOMER
- BRENDA:   2.7.9.3
- HAMAP:   MF_00625
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061
- PIRSF:   PIRSF036407
- TIGRFAMs:   TIGR00476

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =2.7.9.3

Molecular weight: Translated: 36624; Mature: 36492

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: ACT_SITE 17-17

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPAIRLTQYSHGAGCGCKISPKVLDKILHTEQQKFFDPRLLVGNETRDDAAVYDIGNG
CCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCC
VGIISTTDFFMPIVDDPFDFGRIAATNAISDVYAMGGKPIMAIAILGWPIDKLAPEIAQQ
EEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHH
VIEGGRYVCQQAGISLAGGHSIDAPEPILGLAVTGIVSTEQVKKNSAAKPGCKLFLTKPL
HHHCCHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
GIGILTTAEKKSKLRPEHRGLATETMCQLNKPGADFAHIPGVTAMTDVTGFGLLGHLSEI
CCEEEEECHHHHHCCHHHCCCHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
CQGSGVQAILHYSAIPRLPAVEDYIAEGCVPGGTGRNFDSYGHLIGNMSDLQKQLLCDPQ
HCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCC
TSGGLLLAVLPDAEADVQAIAAQHGMTLSPIGELTSADSRRALIEIVV
CCCCEEEEECCCCCHHHHHHHHHCCCEECCCHHHHCCCCCCEEEEEEC
>Mature Secondary Structure 
ASPAIRLTQYSHGAGCGCKISPKVLDKILHTEQQKFFDPRLLVGNETRDDAAVYDIGNG
CCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCC
VGIISTTDFFMPIVDDPFDFGRIAATNAISDVYAMGGKPIMAIAILGWPIDKLAPEIAQQ
EEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHH
VIEGGRYVCQQAGISLAGGHSIDAPEPILGLAVTGIVSTEQVKKNSAAKPGCKLFLTKPL
HHHCCHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
GIGILTTAEKKSKLRPEHRGLATETMCQLNKPGADFAHIPGVTAMTDVTGFGLLGHLSEI
CCEEEEECHHHHHCCHHHCCCHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
CQGSGVQAILHYSAIPRLPAVEDYIAEGCVPGGTGRNFDSYGHLIGNMSDLQKQLLCDPQ
HCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCC
TSGGLLLAVLPDAEADVQAIAAQHGMTLSPIGELTSADSRRALIEIVV
CCCCEEEEECCCCCHHHHHHHHHCCCEECCCHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430