BacMap

Definition	Yersinia pestis CO92 chromosome, complete genome.
Accession	NC_003143
Length	4,653,728

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The map label for this gene is fadD

Identifier: 218929181

GI number: 218929181

Start: 2354492

End: 2356180

Strand: Direct

Name: fadD

Synonym: YPO2074

Alternate gene names: 218929181

Gene position: 2354492-2356180 (Clockwise)

Preceding gene: 218929180

Following gene: 218929182

Centisome position: 50.59

GC content: 48.49

Gene sequence:

>1689_bases
TTGGAAAAAGTATGGCTAAAGCGCTATCCGGCAGATGTCCCCGCAGAGATTGATCCGGACCGCTATTCATCTTTGATAGA
AATGTTTGAGAACGCGGCGTTGCGTTATGCGGACCAACCCGCATTTATTAATATGGGCGAGGTCATGACTTTTCGTAAGC
TGGAAGAGCGCAGCCGTGCTTTTGCTGCCTATCTACAGCAAGGTCTGGGGTTACAGAAAGGTGACCGTGTTGCACTGATG
ATGCCAAATTTACTGCAATATCCTATCGCTTTGTTTGGTGTTCTGCGGGCAGGTATGATTGTCGTGAATGTTAATCCGCT
GTATACCCCGCGTGAACTTGAGCATCAACTTAGTGATAGCGGAGCCGTGGCCATCGTTATTGTTTCCAACTTCGCCCACA
CACTGGAAAAAGTTGTCTTTAAAACCCAGGTCCGGCATGTGATTTTGACCCGAATGGGTGATCAACTCTCGGCAGCAAAA
GGGACGTTGGTTAACTTCGTGGTGAAATACATTAAGCGTCTGGTGCCGAAGTACTATCTGCCCGATGCCATTTCATTTCG
TACCGTATTGCAAAAAGGGCGTCGAATGCAATACGTCAAACCGGATGTTATCAACACGGATACGGCATTCTTGCAATATA
CCGGCGGGACTACGGGTGTCGCGAAAGGTGCCATATTGACACACCGCAACATGCAATCAAATCTGGAACAGGCAAAAGCG
GCCTATGCACCGTTGCTTCAACCTGGCCGTGATTTGGTGGTCACGGCTCTGCCTCTCTACCATATCTTTGCATTGACGGT
AAATTGCCTGCTATTTATCGAGTTGGGGGGGCGCAGTTTATTGATAACCAACCCACGAGATATCCCCGGTATGGTTAAAG
AACTGAGTCGTTATCCATTTACCGCGATAACAGGGGTCAATACGTTATTTAATGCATTATTGAATAATGAAGAGTTTACC
CATTTGGATTTCTCCACCTTGCGCCTTTCGGTGGGCGGCGGTATGCCAGTGCAGAAAGCCGTGGCCGAAAAGTGGGAAAC
GCTGACGGGTAAGCATCTACTGGAGGGTTACGGTTTGACTGAATGCTCACCTTTAGTTACCGGTAACCCTTATGATCTGA
AACATTACAGCGGCAGTATTGGTTTACCGGTACCTTCGACAGATGTTCGGCTGCGCGATGATGATGGCAATGACGTAGAA
TTAGGCAAGCCGGGTGAACTATGGGTGCGTGGGCCACAAGTTATGTTAGGCTATTGGCAGCGGCCAGATGCCACGGATGA
CGTCCTGAAAGACGGCTGGCTGGCGACAGGTGATATTGCGACGATGGATGAGGACGGTTTCTTGCGCATCGTTGACCGTA
AGAAGGACATGATTCTGGTTTCTGGTTTTAACGTCTACCCCAATGAGATTGAAGAGGTGGTAGCGTTACATGCGAAAGTG
CTGGAGTCTGCTGTGATTGGCGTGCCTAATGAGGTCTCCGGCGAGGCAGTAAAAGTCTTTGTTGTTAAAAATGATGCATC
ACTGACACCTGAAGAATTACTAACGCATTGCCGTCGCTACCTTACCGGGTATAAAGTACCGAAAATTGTAGAGTTCCGTG
ACGAATTGCCGAAGTCGAATGTGGGTAAAATATTGCGCAGGGAACTACGTGACGAAGAAGTTAAGGTGGGTACGACAGAC
GCAGCTTAA

Upstream 100 bases:

>100_bases
TTTAAAAACAAACTGGTAAGCTGAGTTAAAATATTGTTAATGTTCTGATGTGAATTTGCGTTTTACCATGGCGACCAATA
ATAATTTTAGGAGTGTTACC

Downstream 100 bases:

>100_bases
CTTGACGGAGTCACTAAATCATCAACAACGCCGGTTATCACCGGCGTTGTTGTGTTTGTTATCGAACTATAGCCAATAGA
TTTTAAGAAACAGGAAGGCG

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRAFAAYLQQGLGLQKGDRVALM
MPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDSGAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAK
GTLVNFVVKYIKRLVPKYYLPDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKA
AYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPFTAITGVNTLFNALLNNEEFT
HLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLTECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVE
LGKPGELWVRGPQVMLGYWQRPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKV
LESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSNVGKILRRELRDEEVKVGTTD
AA

Sequences:

>Translated_562_residues
MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRAFAAYLQQGLGLQKGDRVALM
MPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDSGAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAK
GTLVNFVVKYIKRLVPKYYLPDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKA
AYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPFTAITGVNTLFNALLNNEEFT
HLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLTECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVE
LGKPGELWVRGPQVMLGYWQRPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKV
LESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSNVGKILRRELRDEEVKVGTTD
AA
>Mature_562_residues
MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRAFAAYLQQGLGLQKGDRVALM
MPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDSGAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAK
GTLVNFVVKYIKRLVPKYYLPDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKA
AYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPFTAITGVNTLFNALLNNEEFT
HLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLTECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVE
LGKPGELWVRGPQVMLGYWQRPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKV
LESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSNVGKILRRELRDEEVKVGTTD
AA

Specific function: Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Membrane; Peripheral membrane protein (Potential). Note=Partially membrane-associated (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family

Homologues:

Organism=Homo sapiens, GI156151445, Length=553, Percent_Identity=31.1030741410488, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI38505220, Length=526, Percent_Identity=30.7984790874525, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI42544132, Length=544, Percent_Identity=29.7794117647059, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI115511026, Length=529, Percent_Identity=27.5992438563327, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI157311624, Length=523, Percent_Identity=27.5334608030593, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI157311622, Length=523, Percent_Identity=27.5334608030593, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI58082049, Length=523, Percent_Identity=27.3422562141491, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI187761345, Length=559, Percent_Identity=27.0125223613596, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI187761343, Length=559, Percent_Identity=27.0125223613596, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI122937307, Length=269, Percent_Identity=35.3159851301115, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI40807491, Length=510, Percent_Identity=26.6666666666667, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI42794760, Length=337, Percent_Identity=28.486646884273, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI42794758, Length=337, Percent_Identity=28.486646884273, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI42794756, Length=337, Percent_Identity=28.486646884273, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI57165410, Length=338, Percent_Identity=28.698224852071, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI57165412, Length=335, Percent_Identity=28.0597014925373, Blast_Score=109, Evalue=8e-24,
Organism=Homo sapiens, GI13325057, Length=559, Percent_Identity=24.865831842576, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI62865631, Length=568, Percent_Identity=22.1830985915493, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI13325055, Length=568, Percent_Identity=22.1830985915493, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI42544134, Length=360, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI27477105, Length=560, Percent_Identity=24.4642857142857, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI195947378, Length=426, Percent_Identity=23.7089201877934, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI13236579, Length=518, Percent_Identity=24.1312741312741, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI42794754, Length=382, Percent_Identity=24.869109947644, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI42794752, Length=382, Percent_Identity=24.869109947644, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI28416953, Length=123, Percent_Identity=37.3983739837398, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI13375727, Length=547, Percent_Identity=22.3034734917733, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI8923896, Length=123, Percent_Identity=36.5853658536585, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI253970489, Length=123, Percent_Identity=36.5853658536585, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788107, Length=552, Percent_Identity=80.2536231884058, Blast_Score=934, Evalue=0.0,
Organism=Escherichia coli, GI221142682, Length=554, Percent_Identity=28.3393501805054, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI145693145, Length=551, Percent_Identity=27.2232304900181, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1789201, Length=500, Percent_Identity=25.8, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1786810, Length=534, Percent_Identity=24.3445692883895, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790505, Length=527, Percent_Identity=23.5294117647059, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786801, Length=559, Percent_Identity=23.7924865831843, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786529, Length=571, Percent_Identity=23.8178633975482, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788595, Length=316, Percent_Identity=22.7848101265823, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560308, Length=568, Percent_Identity=29.0492957746479, Blast_Score=208, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI32563687, Length=517, Percent_Identity=28.8201160541586, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17559526, Length=531, Percent_Identity=31.4500941619586, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17558820, Length=522, Percent_Identity=28.3524904214559, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71994694, Length=502, Percent_Identity=27.0916334661355, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71994703, Length=502, Percent_Identity=27.0916334661355, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71994690, Length=502, Percent_Identity=27.0916334661355, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17557194, Length=525, Percent_Identity=28.5714285714286, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17531443, Length=556, Percent_Identity=27.8776978417266, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17538037, Length=544, Percent_Identity=27.9411764705882, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71996755, Length=536, Percent_Identity=25.3731343283582, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71985884, Length=358, Percent_Identity=30.7262569832402, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560140, Length=361, Percent_Identity=28.808864265928, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17556552, Length=491, Percent_Identity=24.6435845213849, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17510401, Length=329, Percent_Identity=26.7477203647416, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17564090, Length=181, Percent_Identity=35.3591160220994, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507435, Length=526, Percent_Identity=24.9049429657795, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147511, Length=359, Percent_Identity=25.0696378830084, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982997, Length=581, Percent_Identity=23.2358003442341, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71983001, Length=581, Percent_Identity=23.2358003442341, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25141359, Length=344, Percent_Identity=23.8372093023256, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17556356, Length=214, Percent_Identity=24.7663551401869, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17553312, Length=221, Percent_Identity=27.6018099547511, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319699, Length=497, Percent_Identity=26.7605633802817, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319264, Length=574, Percent_Identity=25.9581881533101, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323182, Length=588, Percent_Identity=25, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324893, Length=450, Percent_Identity=24.8888888888889, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320852, Length=356, Percent_Identity=25.561797752809, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859661, Length=516, Percent_Identity=35.6589147286822, Blast_Score=254, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24581924, Length=556, Percent_Identity=28.7769784172662, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI21355181, Length=500, Percent_Identity=27.4, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19922652, Length=533, Percent_Identity=26.266416510319, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI62472339, Length=563, Percent_Identity=25.3996447602131, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24667955, Length=547, Percent_Identity=25.5941499085923, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24648260, Length=289, Percent_Identity=31.8339100346021, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24653035, Length=238, Percent_Identity=31.9327731092437, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356947, Length=238, Percent_Identity=32.7731092436975, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24656500, Length=521, Percent_Identity=26.4875239923225, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI161076582, Length=246, Percent_Identity=31.3008130081301, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356441, Length=515, Percent_Identity=23.3009708737864, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28573631, Length=571, Percent_Identity=22.9422066549912, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI20130353, Length=572, Percent_Identity=23.2517482517483, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281365686, Length=239, Percent_Identity=28.4518828451883, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20130357, Length=347, Percent_Identity=23.9193083573487, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667959, Length=515, Percent_Identity=24.4660194174757, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648255, Length=242, Percent_Identity=30.5785123966942, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24648257, Length=231, Percent_Identity=32.9004329004329, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24648253, Length=242, Percent_Identity=30.5785123966942, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21358303, Length=310, Percent_Identity=25.8064516129032, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI62471681, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI62471687, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24586634, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI22026970, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI62471689, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62471679, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62471683, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62471685, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586636, Length=508, Percent_Identity=24.2125984251968, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24666501, Length=323, Percent_Identity=27.8637770897833, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24666497, Length=323, Percent_Identity=27.8637770897833, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281366413, Length=323, Percent_Identity=27.8637770897833, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24583465, Length=565, Percent_Identity=23.716814159292, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583463, Length=565, Percent_Identity=23.716814159292, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364798, Length=565, Percent_Identity=23.716814159292, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LCFA_YERPE (Q8ZES9)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AB0253
- RefSeq:   NP_669545.1
- RefSeq:   NP_993258.1
- RefSeq:   YP_002347056.1
- ProteinModelPortal:   Q8ZES9
- SMR:   Q8ZES9
- GeneID:   1147183
- GeneID:   1174912
- GeneID:   2766250
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO2074
- KEGG:   ypk:y2236
- KEGG:   ypm:YP_1917
- HOGENOM:   HBG547964
- OMA:   IDASPYP
- ProtClustDB:   PRK08974
- BioCyc:   YPES187410:Y2236-MONOMER
- BioCyc:   YPES214092:YPO2074-MONOMER
- BRENDA:   6.2.1.3
- GO:   GO:0016020
- InterPro:   IPR020845
- InterPro:   IPR000873

Pfam domain/function: PF00501 AMP-binding

EC number: =6.2.1.3

Molecular weight: Translated: 62640; Mature: 62640

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHH
FAAYLQQGLGLQKGDRVALMMPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDS
HHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCC
GAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAKGTLVNFVVKYIKRLVPKYYL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCC
PDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKA
CCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCCCHHCCEEEECCCHHHHHHHHHH
AYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPF
HHHHHCCCCCCCEEHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCHHHHHHHHHCCC
TAITGVNTLFNALLNNEEFTHLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLT
HHHHHHHHHHHHHHCCCCCEEEEHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVELGKPGELWVRGPQVMLGYWQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEEECCCEEEEECC
RPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKV
CCCCCHHHHHCCCEECCCEEEECCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
LESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSN
HHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCH
VGKILRRELRDEEVKVGTTDAA
HHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHH
FAAYLQQGLGLQKGDRVALMMPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDS
HHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCC
GAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAKGTLVNFVVKYIKRLVPKYYL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCC
PDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKA
CCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCCCHHCCEEEECCCHHHHHHHHHH
AYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPF
HHHHHCCCCCCCEEHHHHHHHHHHHHHHHHEEEEECCCEEEEECCCCCHHHHHHHHHCCC
TAITGVNTLFNALLNNEEFTHLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLT
HHHHHHHHHHHHHHCCCCCEEEEHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
ECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVELGKPGELWVRGPQVMLGYWQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEEECCCEEEEECC
RPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKV
CCCCCHHHHHCCCEECCCEEEECCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
LESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSN
HHHHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCH
VGKILRRELRDEEVKVGTTDAA
HHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430