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The map label for this gene is cutC [H]

Identifier: 218929155

GI number: 218929155

Start: 2326253

End: 2327017

Strand: Direct

Name: cutC [H]

Synonym: YPO2048

Alternate gene names: 218929155

Gene position: 2326253-2327017 (Clockwise)

Preceding gene: 218929154

Following gene: 218929160

Centisome position: 49.99

GC content: 49.15

Gene sequence:

>765_bases
ATGACTAAATTGGAAGTTTGTTGCTATAGCGTTGATTGTGCACAAATAGCAGAAAAGGCAGGAGCCGACCGGGTTGAATT
GTGCTGTGGTCAGTCTGAAGGGGGGGTGACGCCGAGTGTCGGCGCATTAATGCAGGCCAGAGAAACCGTGACTATCCCGG
TTCATCCGATAGTTCGGCCACGTGGTGGTGATTTTTGTTACAGCAGCAATGATTTTACTATTATGAAAAATGATATTGCG
CGGATCCGTGACTTGGGCTTTGCTGGCGTCGTCGTTGGCGTACTGGATACGGATGGGCATATCGATATGCCACGGATGCG
GGAGATTATGTCAGTAAGTGGTTCACTGGCGGTAACCTTCCATCGCGCATTTGATATGTGCCAAAATCCGATGATTGCCT
TAAAGCAATTGGCTGAACTTAATGTGGCGCGTATTTTAACCTCAGGGCAGCAGCAAAATGCTGAATTGGGTTTAGCTCTG
TTGAAAGATTTGGTTGCAGCAACCAAGGATCAAGGCCCGATTATTATGGCAGGGGCCGGGGTGCGGTTGACGAATATGCA
GAAGTTTATTGATGCAGGGATTCGTGAATTACACAGTTCTGCCGGGCGGACGGTGCCATCAACCATGCGATACCGTAAAG
CCGGGGTGACGATGTGCGCCGACAGTGATGTCGATGAGTTTTCTCACTATTGTGTTGATGGTGAGGTCGTTGAAGCTATG
AAGAGTTTATTGGTTATGGGGTCGCCTCTTGCCAAGCACACCTAG

Upstream 100 bases:

>100_bases
GAGAGAGATATTCGGCATTTTGTTAATTTGCCAGTGAATCATTAATTTTCAGGTGGTTTACACTCACTGTCGCAGTGAAA
TCTGTCAAACGGGGGAGATA

Downstream 100 bases:

>100_bases
TGCGCCTAATTCAGTACACAATATATTGATATATATCCCTCTTACGTGAAGTTGCAGGGTGGTTAGCTGCTCTCAATTAT
CTGAGTTACGGGTGTGTCAA

Product: copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGVTPSVGALMQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIA
RIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLAL
LKDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAM
KSLLVMGSPLAKHT

Sequences:

>Translated_254_residues
MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGVTPSVGALMQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIA
RIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLAL
LKDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAM
KSLLVMGSPLAKHT
>Mature_253_residues
TKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGVTPSVGALMQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIAR
IRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALL
KDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAMK
SLLVMGSPLAKHT

Specific function: Involved in copper homeostasis [H]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=241, Percent_Identity=42.3236514522822, Blast_Score=185, Evalue=4e-47,
Organism=Escherichia coli, GI87081995, Length=244, Percent_Identity=56.1475409836066, Blast_Score=296, Evalue=9e-82,
Organism=Caenorhabditis elegans, GI17556905, Length=202, Percent_Identity=30.6930693069307, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355415, Length=251, Percent_Identity=36.6533864541833, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 27327; Mature: 27196

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGVTPSVGALMQARETVTIPVHPIVRP
CCCEEEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCCCCC
RGGDFCYSSNDFTIMKNDIARIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTF
CCCCEEECCCCCEEEHHHHHHHHHCCHHHEEEEEEECCCCCCCHHHHHHHHCCCCEEEHH
HRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALLKDLVAATKDQGPIIMAGAG
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
VRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAM
EEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCHHHHHHHCCCHHHHHHH
KSLLVMGSPLAKHT
HHHHHHCCCHHCCC
>Mature Secondary Structure 
TKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGVTPSVGALMQARETVTIPVHPIVRP
CCEEEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCCCCC
RGGDFCYSSNDFTIMKNDIARIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTF
CCCCEEECCCCCEEEHHHHHHHHHCCHHHEEEEEEECCCCCCCHHHHHHHHCCCCEEEHH
HRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALLKDLVAATKDQGPIIMAGAG
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCC
VRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAM
EEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCHHHHHHHCCCHHHHHHH
KSLLVMGSPLAKHT
HHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA