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The map label for this gene is argS [H]

Identifier: 218929153

GI number: 218929153

Start: 2323093

End: 2324823

Strand: Reverse

Name: argS [H]

Synonym: YPO2046

Alternate gene names: 218929153

Gene position: 2324823-2323093 (Counterclockwise)

Preceding gene: 218929156

Following gene: 218929147

Centisome position: 49.96

GC content: 49.91

Gene sequence:

>1731_bases
GTGAATATTCAGGCTCTTCTCTCAGATAAAGTCAGCCAGGCGCTGATTGCAGCAGGTGCTCCCGCAGATTGCGAAGCTCA
AGTTCGCCAATCTGCCAAAGCTCAATTTGGCGATTATCAAGCTAACGGTGTGATGGCCGTTGCCAAAAAACTTGGCATGC
AACCCCGACAACTGGCAGAAAGAGTCGTTGAACTGCTCGACCTTACAGGTATCGCCAGTAAGATTGAAATTGCAGGCCCC
GGTTTTATCAATATTTTTCTGGATCGTCAGTGGGTGGCCGAGAAAGTCGAATATGCTCTGACTGCGCCTAAATTGGGCGT
CGCGCCTGTCGAACCGCAAACTATCGTAGTCGATTATTCAGCACCTAACGTGGCTAAACAGATGCACGTTGGTCACCTGC
GATCCACCATTATTGGTGATGCTGCAGTACGGACATTGGCGTTTTTGGGCCATAACGTTATCCGTGCCAACCACGTCGGT
GACTGGGGTACTCAGTTTGGCATGTTGATCGCCTACCTGGAGAAAATGCAGAACGAAAATGCCAGTGATATGGGGCTATC
GGATCTGGAGCTTTTCTATCAACAAGCGAAGAAAACCTACGACGAAGACGAAGAGTTTGCTCTGCGTGCCCGTGCCTATG
TCGTAAAACTGCAAAGTGGGGACGAATACTGCCGTCAAATGTGGCGTAAATTGGTGGATATCACCATGGCACAAAACCAG
GTTGCCTATGACCGCCTGAATGTCACCTTGACCAAAGACGACGTAATGGGTGAAAGCCTGTACAATGCGATGCTGCCAGA
GATTGTCGCGGATTTGAAAGCCAAAGGGTTGGCCGTCGAGAGCGAAGGTGCGACCGTTGTCTATCTGGATGAATATAAGA
ATAAAGACGGTGAGCCAATGGGCGTCATCATCCAGAAAAAAGATGGCGGCTACCTCTACACTACCACCGACATTGCCTGT
GCCAAATACCGTTACGAAACGCTGGGCGCAGACCGGATACTCTATTACATCGATAGCCGCCAGCATCAGCATTTGATGCA
AGCCTGGACCATCGTGCGTAAAGCCGGTTATGTGCCAGAATCCGTGCCACTGGAACACCACATGTTCGGCATGATGCTGG
GCAAAGATGGCAAACCGTTTAAAACCCGCTCTGGTGGTACCGTCAAATTATCCGATTTACTGGACGAGGCGGTTGAACGT
GCTGGCAAGTTGATTGCCGAGAAAAACCCGGATATGCCTGCCGATGAATTGAAGCAAGTGATCAATGCGGTGGGGATTGG
CGCGGTGAAATATGCCGATTTGTCCAAGAGCCGAACCACAGACTATATTTTCGATTGGGATAATATGCTGGCGTTGGATG
GCAATACCGCGCCTTATATGCAATATGCTTATACTCGCGTGGTTTCAGTATTTAGACGTGCGGGTGTTGATGAAACCAGC
CTGACGCTGCCATTAGTGGTTACAGAAGATCGCGAAGCCACCTTGGCGACCCGCCTGTTGCAGTTTGAAGAGATCATCAC
CACGGTGGCACGCGAAGGTACACCGCATGTCATGTGTTCTTATCTCTATGATTTAGCAGGCTTGTTCTCCAGCTTCTACG
AGCATTGCCAGATCCTGAATGCAGAGAGCGAAGAGATCCGCCAAAGCCGCTTGAAATTGGCAATGTTAACCGCTAAAACG
CTGAAACAAGGTCTGGACACCTTGGGTATTCAAACCGTTGAGCGGATGTAA

Upstream 100 bases:

>100_bases
GTAACTGACACAGAAATGAGTCACTGGCACAGAAATGTGACTGATCCAGAATTTTTTGTGCATAATTAATCTGTCTTTCG
TATGTAATTAAGGTAACCCG

Downstream 100 bases:

>100_bases
ATCGTCAAAAAAGGCCCCTCGGGGCCTTAAAAAACGATTAGCTTGTGTGCTTACATTTCATCTTGATTAGCGAGGTTTTG
GGCTAAAAGGGAGTTCATCA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGP
GFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVER
AGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETS
LTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKT
LKQGLDTLGIQTVERM

Sequences:

>Translated_576_residues
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGP
GFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVER
AGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETS
LTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKT
LKQGLDTLGIQTVERM
>Mature_576_residues
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGP
GFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVG
DWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVER
AGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETS
LTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKT
LKQGLDTLGIQTVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=572, Percent_Identity=37.5874125874126, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI197100773, Length=535, Percent_Identity=29.5327102803738, Blast_Score=210, Evalue=3e-54,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=83.0155979202773, Blast_Score=1001, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=597, Percent_Identity=37.3534338358459, Blast_Score=367, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71985068, Length=565, Percent_Identity=37.5221238938053, Blast_Score=354, Evalue=9e-98,
Organism=Caenorhabditis elegans, GI17532153, Length=384, Percent_Identity=28.3854166666667, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=32.3529411764706, Blast_Score=246, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6321883, Length=538, Percent_Identity=27.6951672862454, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI18859963, Length=567, Percent_Identity=38.4479717813051, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI28571570, Length=487, Percent_Identity=29.3634496919918, Blast_Score=170, Evalue=3e-42,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64142; Mature: 64142

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
RVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYS
HHHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
APNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
ASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
CCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCH
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPM
HEEEHEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQV
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
INAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETS
HHHHCCCCEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILN
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
AESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHH
RVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYS
HHHHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECC
APNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
ASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQ
CCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCH
VAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPM
HEEEHEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCE
GVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPE
EEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCC
SVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQV
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
INAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETS
HHHHCCCCEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
LTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILN
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
AESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA