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The map label for this gene is shlB [H]

Identifier: 218929151

GI number: 218929151

Start: 2316429

End: 2318102

Strand: Direct

Name: shlB [H]

Synonym: YPO2044

Alternate gene names: 218929151

Gene position: 2316429-2318102 (Clockwise)

Preceding gene: 218929150

Following gene: 218929152

Centisome position: 49.78

GC content: 36.8

Gene sequence:

>1674_bases
GTGTTATGGCAAATGAATATTTTTTTTAGAAAAAAATATATGATTATTTTGTTGCTTAGTAATGCTGTTTTAGCAACAGA
GAATAATAAAAATAGATTAAATGATAATGTGGTATCACACGCTGACATAGATGTGCGTAATGAATATAACGAGGAAGGCA
ATAGAGTAGGAAAACGTTTTTTTTCTACAAACCATCATAGTGTTGCATCACAGAAAAAAATCTCCCCAGAGAAAATATGC
CTGCCAATTACTGGGGTATTTTTGCAAGGGAATACATTACTGTCGTCGCAAGACTTAAATCAGATTGATCATATTCTTGG
TGAATGCATTAGTGAAGATGATATTAATATCTTAGCCAAGGAAGTGACTCGATTATATTTGTCTAAAGGTTATCTGGCGG
CCAGAGTCAATTTCATTCCATTAAATAATGCGGGGGAGTTGGGACTGAATGTGACTGAGGGTATTGTTGAAAAAATTGAA
GGTGGAGGACGAAGAGTCAACCCTTATTTTATATTCCCTAACTTTATTGATAAACCCCTTCGGTTATCCGAGCTTGATCA
GGCCATCGATCAGGCTAACAGACTACGATCAAATAAAGTAAACGTCGATATCTTACCAGGAAGTCAGGCGGGCAAATCAA
TTATTAGAATTAATAATGTCAATAATAAACCTTGGAGCTTATCGACCGTCATTGATAATTATGGATATAAAAATTCTGAT
GAGTGGCAAGCAAGAGTGTCACTGGCTTTAGATAGCCCATTCGGACTATCTGATTCTATTAATTTTAATGCTAATCGCAC
GCTAGAGAATGCAAAGAATCGCTATAAGAATGATTTTACTGTTTCTTATTCGGTACCTTATGGTGCATTAACTTTCAGTG
CTCTTGCTAATTATCTGGAATACCGGCGCTATGAGAAATTAAAAAATGGGACAGTGAATTTTAATGGTAACTCACAGCAG
TATAACTTCCGTACTGATTATATGTTCCATCGTACACAAAAGCAGATAAACAGTTTAAGTATGCAAGTAGAGCACAAACA
GATTAATAACTATGTCGATGAGGCAAAAGTAGGTGTCTACAGTTATCGATTTACTAATCTTGAATTAGGTGTCAATCAAT
TTCGTATTCTTCCTCATGGTTCAGTGAATGTTAATGCGGCAATAAAAAGAGGTGTGCCATGGTTTGGTACTCATCAGAAA
AATAAAATAAATGCAGTACAATTTACCACAGGAAAATTGATGGTTAATTTTAATCACAATTTCTCTCTATTAAATTCTCC
GTACCAATTTGATCATGCTTTAGTTGGGCAATACAGTAAGAATTATGCGCCTTCTCCTGAGTGGATAAGTTTGACTGAAC
GTAATGCCATTAGAGGATTTAGTCGTAGTTCACAATCGGCAGATCATGGTTGGTATATGAAAAATACGTTATCCAAGCAC
TTTTTTATGGGGAATATACTTTTTACCCCTCGAATGGGTGTTGATGGCGGACGTGCTTTAAAGCATGGAAGTCAGCAAGG
GTGGCAAAGTAATGCGGGTGTGAGTGCTGGTATATCCATGCGCTATCACCAAGCATTATTTGATGTGGAAGCCAGCCGTG
GTTGGTGGCTTTCCGATAGTAATAAACAGAACGAACCTGTACAGGTATTGGGCCGTATAGCTTATACCTTCTAA

Upstream 100 bases:

>100_bases
ATGATTTTTTTAAGAACTAAATTTTGGTTTAACCCACACATCTAGTGTGTTGTTAATCCTCTGTTTTTTAAATTCTATCG
CACATTGGATTCATTCACGG

Downstream 100 bases:

>100_bases
CTCAACGTAATTTAAATAAGGTTATTTTAATGAAAATAAATAAATTTAAACTTTCCCCAGCAGGAAAGTTGACGGTTATC
TTATCTTTAATTCTTACTCC

Product: putative hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MLWQMNIFFRKKYMIILLLSNAVLATENNKNRLNDNVVSHADIDVRNEYNEEGNRVGKRFFSTNHHSVASQKKISPEKIC
LPITGVFLQGNTLLSSQDLNQIDHILGECISEDDINILAKEVTRLYLSKGYLAARVNFIPLNNAGELGLNVTEGIVEKIE
GGGRRVNPYFIFPNFIDKPLRLSELDQAIDQANRLRSNKVNVDILPGSQAGKSIIRINNVNNKPWSLSTVIDNYGYKNSD
EWQARVSLALDSPFGLSDSINFNANRTLENAKNRYKNDFTVSYSVPYGALTFSALANYLEYRRYEKLKNGTVNFNGNSQQ
YNFRTDYMFHRTQKQINSLSMQVEHKQINNYVDEAKVGVYSYRFTNLELGVNQFRILPHGSVNVNAAIKRGVPWFGTHQK
NKINAVQFTTGKLMVNFNHNFSLLNSPYQFDHALVGQYSKNYAPSPEWISLTERNAIRGFSRSSQSADHGWYMKNTLSKH
FFMGNILFTPRMGVDGGRALKHGSQQGWQSNAGVSAGISMRYHQALFDVEASRGWWLSDSNKQNEPVQVLGRIAYTF

Sequences:

>Translated_557_residues
MLWQMNIFFRKKYMIILLLSNAVLATENNKNRLNDNVVSHADIDVRNEYNEEGNRVGKRFFSTNHHSVASQKKISPEKIC
LPITGVFLQGNTLLSSQDLNQIDHILGECISEDDINILAKEVTRLYLSKGYLAARVNFIPLNNAGELGLNVTEGIVEKIE
GGGRRVNPYFIFPNFIDKPLRLSELDQAIDQANRLRSNKVNVDILPGSQAGKSIIRINNVNNKPWSLSTVIDNYGYKNSD
EWQARVSLALDSPFGLSDSINFNANRTLENAKNRYKNDFTVSYSVPYGALTFSALANYLEYRRYEKLKNGTVNFNGNSQQ
YNFRTDYMFHRTQKQINSLSMQVEHKQINNYVDEAKVGVYSYRFTNLELGVNQFRILPHGSVNVNAAIKRGVPWFGTHQK
NKINAVQFTTGKLMVNFNHNFSLLNSPYQFDHALVGQYSKNYAPSPEWISLTERNAIRGFSRSSQSADHGWYMKNTLSKH
FFMGNILFTPRMGVDGGRALKHGSQQGWQSNAGVSAGISMRYHQALFDVEASRGWWLSDSNKQNEPVQVLGRIAYTF
>Mature_557_residues
MLWQMNIFFRKKYMIILLLSNAVLATENNKNRLNDNVVSHADIDVRNEYNEEGNRVGKRFFSTNHHSVASQKKISPEKIC
LPITGVFLQGNTLLSSQDLNQIDHILGECISEDDINILAKEVTRLYLSKGYLAARVNFIPLNNAGELGLNVTEGIVEKIE
GGGRRVNPYFIFPNFIDKPLRLSELDQAIDQANRLRSNKVNVDILPGSQAGKSIIRINNVNNKPWSLSTVIDNYGYKNSD
EWQARVSLALDSPFGLSDSINFNANRTLENAKNRYKNDFTVSYSVPYGALTFSALANYLEYRRYEKLKNGTVNFNGNSQQ
YNFRTDYMFHRTQKQINSLSMQVEHKQINNYVDEAKVGVYSYRFTNLELGVNQFRILPHGSVNVNAAIKRGVPWFGTHQK
NKINAVQFTTGKLMVNFNHNFSLLNSPYQFDHALVGQYSKNYAPSPEWISLTERNAIRGFSRSSQSADHGWYMKNTLSKH
FFMGNILFTPRMGVDGGRALKHGSQQGWQSNAGVSAGISMRYHQALFDVEASRGWWLSDSNKQNEPVQVLGRIAYTF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 63368; Mature: 63368

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWQMNIFFRKKYMIILLLSNAVLATENNKNRLNDNVVSHADIDVRNEYNEEGNRVGKRF
CEEEEEEEEECCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHH
FSTNHHSVASQKKISPEKICLPITGVFLQGNTLLSSQDLNQIDHILGECISEDDINILAK
HCCCCCHHHHHHCCCCCCEEEEEEEEEEECCEEECCCCHHHHHHHHHHHCCCCCHHHHHH
EVTRLYLSKGYLAARVNFIPLNNAGELGLNVTEGIVEKIEGGGRRVNPYFIFPNFIDKPL
HHHHHHHHCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEECEEEECHHHCCCCC
RLSELDQAIDQANRLRSNKVNVDILPGSQAGKSIIRINNVNNKPWSLSTVIDNYGYKNSD
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCEEHHHHHHCCCCCCCC
EWQARVSLALDSPFGLSDSINFNANRTLENAKNRYKNDFTVSYSVPYGALTFSALANYLE
CCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
YRRYEKLKNGTVNFNGNSQQYNFRTDYMFHRTQKQINSLSMQVEHKQINNYVDEAKVGVY
HHHHHHHCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHEEEE
SYRFTNLELGVNQFRILPHGSVNVNAAIKRGVPWFGTHQKNKINAVQFTTGKLMVNFNHN
EEEEEEEEECCCEEEEECCCCCEEEHHHHCCCCCCCCCCCCCEEEEEEEECEEEEEECCC
FSLLNSPYQFDHALVGQYSKNYAPSPEWISLTERNAIRGFSRSSQSADHGWYMKNTLSKH
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHH
FFMGNILFTPRMGVDGGRALKHGSQQGWQSNAGVSAGISMRYHQALFDVEASRGWWLSDS
EEECEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCEEECCC
NKQNEPVQVLGRIAYTF
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLWQMNIFFRKKYMIILLLSNAVLATENNKNRLNDNVVSHADIDVRNEYNEEGNRVGKRF
CEEEEEEEEECCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHH
FSTNHHSVASQKKISPEKICLPITGVFLQGNTLLSSQDLNQIDHILGECISEDDINILAK
HCCCCCHHHHHHCCCCCCEEEEEEEEEEECCEEECCCCHHHHHHHHHHHCCCCCHHHHHH
EVTRLYLSKGYLAARVNFIPLNNAGELGLNVTEGIVEKIEGGGRRVNPYFIFPNFIDKPL
HHHHHHHHCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEECEEEECHHHCCCCC
RLSELDQAIDQANRLRSNKVNVDILPGSQAGKSIIRINNVNNKPWSLSTVIDNYGYKNSD
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCEEHHHHHHCCCCCCCC
EWQARVSLALDSPFGLSDSINFNANRTLENAKNRYKNDFTVSYSVPYGALTFSALANYLE
CCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
YRRYEKLKNGTVNFNGNSQQYNFRTDYMFHRTQKQINSLSMQVEHKQINNYVDEAKVGVY
HHHHHHHCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHEEEE
SYRFTNLELGVNQFRILPHGSVNVNAAIKRGVPWFGTHQKNKINAVQFTTGKLMVNFNHN
EEEEEEEEECCCEEEEECCCCCEEEHHHHCCCCCCCCCCCCCEEEEEEEECEEEEEECCC
FSLLNSPYQFDHALVGQYSKNYAPSPEWISLTERNAIRGFSRSSQSADHGWYMKNTLSKH
EEECCCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCHHHHHHHH
FFMGNILFTPRMGVDGGRALKHGSQQGWQSNAGVSAGISMRYHQALFDVEASRGWWLSDS
EEECEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCEEECCC
NKQNEPVQVLGRIAYTF
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]