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The map label for this gene is mbtI [H]

Identifier: 218929088

GI number: 218929088

Start: 2243988

End: 2245964

Strand: Reverse

Name: mbtI [H]

Synonym: YPO1976

Alternate gene names: 218929088

Gene position: 2245964-2243988 (Counterclockwise)

Preceding gene: 218929096

Following gene: 218929085

Centisome position: 48.26

GC content: 46.89

Gene sequence:

>1977_bases
ATGGTCTTCATTAAGTCCACGCCACTAGAACTGACCCGCAGAAAAAACAGACCACCATCCCTATACACCTACACCTACAC
CTACACCTACACACCTCAGGTTATACCTTCCTCATTATCATTTACCCAAGCTATAGAAACTGCCGAAATGGTGAGGCCTC
AGCCATGGGATAAAAATCATTTATCCCGTTGGCCGTTGTTACATGTAGCGCTCATATTGCCTGATATCCGCCGCTATCAA
CAACAATGTGGAACCCTGCCCAACCGACTCAAACACATCACGGGTTGGCCACTCCCCCCTTTTGGTAGGATAGATAGTCA
ACATTTATCTGCTCAGGCCCGAGAGCCTCTCCCAGAGGGAGTAACATCGCCCATGCCCTGCTCTGGAGAACCGCTTTACT
ATGCGCAGTGTCAACAAACGATCTGTGCTCCCCCACTGACAATGGCGACAAAATTAGTCCAGCGTTATCAAGAGGGTGCC
CGCAATATCTCTCACAGTAAAAGCGGCTCAGAAGGATATTCGTCACTCACTGACAATGAAGAATGGCAACCCTACGCTAT
CTATGAAAAAGACGGTGAGTTCTCGGTCGGTATTGGGCTGGCGGCACTGATAACTGCCTATCCTAATTATGTTCACATAC
GTTACCAGCAGCAAAATGCTCATGGCGATAGCTTTAGCGGCGAACAATTTCAAGAGCGTGTTTGGTTATCCTCCGACATC
GTCGGTAATATTTCATCCGCACTGGCAAGTATCCCGATTAAAGAGTGGCGAGCTTATGGTCTCAGCCAATTGGAATTGGT
TCATCTCTTCCATAACCCGGCGTCTCACGCGGCCCCCGGTACCGCACTACTGCAAATTTTCCTTCCGCTGCATGAATATA
GACTCAATCGCGGCAGCGCTATAATACGCAGTTTGCTTCCCTCTCACTTACCCCAACTGCTTACGATGCTGCAGCAATGT
GACAGTGACCAATATGACAACGCGCCCTCTATCAACAAGTCATCTATCTATAAATCATCTAGTTGTGAACCATCTATTTA
TGAGCCATCTATTTATGAACAACCTGGCGATGAATATGATGAAAATAATCAACGTGCCCATAAGCAAGACAGCCACCTGC
AGACACAAGTAGAAAGAAGCGCCATCGAAATGCAGATACGCCAAACTGACCCTACTATTTTCTGTGATCGGGTAGCAAAA
ACCGTTAATGAAATCAGGCAAGGTAAATATCAGAAAGCCATTTTATCGCGCCAGATACCGCTGCCAAATAATATTAATTT
ACTCGCAAGCTACCAACGTGGGCGCATAAATAACACCTCGGCACGCTCCTATGCTTTCCGGATGCAAGGATTTGAATTAA
TGGGCTTTAGCTCAAAGACTGCCGTGACTGTCTCAGCCAATGGCTGTCTGATCACCCAACTTTTAACCGATACACATGCA
CTGTCGTCAGACCAAACTCAATCGGTGCCACTTCATCATGAATTACGAATTAATACTAAAGATATCACTGAACATACCAG
CTCAATCCTCTCTGTTGTTGCAACGCTAACACCAATCTGTGTACCAGGCTCAGTTGCCATTGTTCCGTATATGAAGGTGC
TTACTTGCGGTAAGGTGCAAAATCTGGCCTCCTGTCTGCAAGGCCAGCTACAAAAAGGCATCAGCCACTGGCAAGCTATG
CAATCCCTGTATCCTGTAGCTGCCGATATTCCTAAAGATCATCTGATGCAAGCAACTCTTCATGAACTGGGATCATGGGA
GGCCTATAGCAGCAGCGTGCTAATGGTTGACAGCAATGGTGCATTGGATGCGACGCTAATTTCAGAGAGCCTTTCCCGTA
AGAATAAAAGATTTGGATTACGAGCCGGAACCGAAATCACCCATCAAGCAGACCCCCTACTCAAGCTAGAAGAGACTCAT
GAGACGCTGATCGCGATTGCCCGTTATCTGGTGTTGCAAACAGCAATGACCGATTAA

Upstream 100 bases:

>100_bases
ACTAACTGGATTAACATAATAATAGTGATGATAGAAATTATCATTAAAATAAATAGAAAAAAATAATTAATCAAAATAAC
TATTACATAAGGATGATGTC

Downstream 100 bases:

>100_bases
CCCCGCTGCCGCCCATTACTACAAAACCAAACCATTATAAAACAAGAGGTCCATATTCGGTTGATGCTCACAATGCCACT
TTGTGAACATAAGGTTAACT

Product: hypothetical protein

Products: NA

Alternate protein names: Mycobactin synthase protein I; Salicylate synthase mbtI [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MVFIKSTPLELTRRKNRPPSLYTYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQ
QQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGA
RNISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDI
VGNISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQC
DSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAK
TVNEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHA
LSSDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQLQKGISHWQAM
QSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETH
ETLIAIARYLVLQTAMTD

Sequences:

>Translated_658_residues
MVFIKSTPLELTRRKNRPPSLYTYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQ
QQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGA
RNISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDI
VGNISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQC
DSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAK
TVNEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHA
LSSDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQLQKGISHWQAM
QSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETH
ETLIAIARYLVLQTAMTD
>Mature_658_residues
MVFIKSTPLELTRRKNRPPSLYTYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNHLSRWPLLHVALILPDIRRYQ
QQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEGVTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGA
RNISHSKSGSEGYSSLTDNEEWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDI
VGNISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSAIIRSLLPSHLPQLLTMLQQC
DSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYDENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAK
TVNEIRQGKYQKAILSRQIPLPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHA
LSSDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQNLASCLQGQLQKGISHWQAM
QSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNGALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETH
ETLIAIARYLVLQTAMTD

Specific function: Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicyl

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family. Salicylate synthase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 700 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR015890
- InterPro:   IPR019996 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 73706; Mature: 73706

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFIKSTPLELTRRKNRPPSLYTYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNH
CEEEECCCHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
LSRWPLLHVALILPDIRRYQQQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEG
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
VTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARNISHSKSGSEGYSSLTDNE
CCCCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDI
CCCCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
VGNISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSA
HHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IIRSLLPSHLPQLLTMLQQCDSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
ENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTVNEIRQGKYQKAILSRQIP
CCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHA
CCCCCCEEEECCCCCCCCCCHHHEEHEECCEEEECCCCCEEEEEECCCEEEHHHHHHHHH
LSSDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQ
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NLASCLQGQLQKGISHWQAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCC
ALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHETLIAIARYLVLQTAMTD
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFIKSTPLELTRRKNRPPSLYTYTYTYTYTPQVIPSSLSFTQAIETAEMVRPQPWDKNH
CEEEECCCHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
LSRWPLLHVALILPDIRRYQQQCGTLPNRLKHITGWPLPPFGRIDSQHLSAQAREPLPEG
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
VTSPMPCSGEPLYYAQCQQTICAPPLTMATKLVQRYQEGARNISHSKSGSEGYSSLTDNE
CCCCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EWQPYAIYEKDGEFSVGIGLAALITAYPNYVHIRYQQQNAHGDSFSGEQFQERVWLSSDI
CCCCEEEEECCCCEEEHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
VGNISSALASIPIKEWRAYGLSQLELVHLFHNPASHAAPGTALLQIFLPLHEYRLNRGSA
HHHHHHHHHHCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
IIRSLLPSHLPQLLTMLQQCDSDQYDNAPSINKSSIYKSSSCEPSIYEPSIYEQPGDEYD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
ENNQRAHKQDSHLQTQVERSAIEMQIRQTDPTIFCDRVAKTVNEIRQGKYQKAILSRQIP
CCCCHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPNNINLLASYQRGRINNTSARSYAFRMQGFELMGFSSKTAVTVSANGCLITQLLTDTHA
CCCCCCEEEECCCCCCCCCCHHHEEHEECCEEEECCCCCEEEEEECCCEEEHHHHHHHHH
LSSDQTQSVPLHHELRINTKDITEHTSSILSVVATLTPICVPGSVAIVPYMKVLTCGKVQ
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
NLASCLQGQLQKGISHWQAMQSLYPVAADIPKDHLMQATLHELGSWEAYSSSVLMVDSNG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCC
ALDATLISESLSRKNKRFGLRAGTEITHQADPLLKLEETHETLIAIARYLVLQTAMTD
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA