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The map label for this gene is hutI [H]

Identifier: 218929084

GI number: 218929084

Start: 2239529

End: 2240749

Strand: Reverse

Name: hutI [H]

Synonym: YPO1972

Alternate gene names: 218929084

Gene position: 2240749-2239529 (Counterclockwise)

Preceding gene: 218929085

Following gene: 218929083

Centisome position: 48.15

GC content: 50.29

Gene sequence:

>1221_bases
ATGGTATCAGTAACTCACTGTGACAGCTTATGGTTCGGGGCCGATATCATTACGATGCGCGGGGGAAATTATCAGTTGAT
TCCGCAAGGGGCAATCGCTGTCACTGGCGATAAGATAGTCTGGATTGGGCCACATGCCGAATTACCGCCTATTCATGCCG
CACGTCAGGTCGTATATGAAGGTGGTCTTATCACCCCTGGATTGATTGACTGTCACACCCATCTCGTGTTTGGCGATGAT
CGTAGCAATGAATTTGAGCAACGCCTTAACGGGGTCAGCTATGCCGAAATTGCTGCTAATGGCGGTGGTATTATTTCAAC
CGTCAGAGCCACACGCCAAGCTAGCGAACAGCAACTACTGGAACAAGCCCTATTTCGTCTGAAGCCCTTACTTGCTGAAG
GGGTGACTACGATTGAGATTAAGTCTGGCTATGGCCTTAATCTTGAAAGTGAAATAAAAATGTTGCGAGTGGCCCGCCGA
TTGGGGGAGTTACTGCCTATTGACGTCAAAACGACTTGTTTGGCCGCCCATGCGCTACCGCCCGAGTTTATCGGGCAGCC
TGATGATTATATTGATGTCGTATGTAATAGCATTATTCCTCAGGTGGCAGTTGAAAACTTAGCCGATGCCGTGGACGCAT
TTTGCGAACATTTAGCTTTTTCACCGGCTCAAGTTGAGCGAGTATTTTTAGCCGCACAAAAAGCCGGGCTACCTGTAAAA
CTGCACGCAGAGCAACTTTCTGCTCTCCGTGGCGCGACTCTGGCCGCTAAATTCCATGCGATATCGGCAGACCATCTGGA
GTACGCGACTGAATCTGATGTCCAGGCTATGGCAAATGCGGGTACTGTCGCAGTCTTACTACCAGGTGCCTACTACTTAT
TGCGGGAAACACAATGCCCCCCAATTGATCTGTTCCGCCAGTATAAGGTCCCCATGGCACTGGCCAGTGATGCCAACCCA
GGGACATCTCCGGTACTTTCACTACGCTTGATGCTCAATATGGCTTGCACGTTATTCCGCATGACACCAGAAGAAGCACT
GGCTGGTGTCACGTGCCACGCAGCTCAAGCTCTTGGTGTACAACAGACTCAAGGTACGTTGGAGACAGGGAAATTAGCTA
ACTGGGTGCATTGGCCCTTATCACACCCAGCCGAGTTAGCTTATTGGTTAGGAGGGCAATTACCTGCCACTGTCGTATTC
CGAGGAGAAGTACGCCCATGA

Upstream 100 bases:

>100_bases
CAAGTTGATTTCGTTCATCCAGTAAATGATTCGGGTGACAAATCTGCCGAGTGCAGCTAACACCGCAGCAACGTCAAATG
AGAAGGGAAAGGGGAAAGAA

Downstream 100 bases:

>100_bases
ATTTAACTGACTCTTACTACTTTCAGGGCGGAAAAATACCTTTGCTCATTAGCATTCCACATGCAGGTACACGCCTGACT
CCCGCAGTTGAAGCTGGCCT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGDD
RSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARR
LGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANP
GTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVF
RGEVRP

Sequences:

>Translated_406_residues
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGDD
RSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARR
LGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANP
GTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVF
RGEVRP
>Mature_406_residues
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYEGGLITPGLIDCHTHLVFGDD
RSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLLEQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARR
LGELLPIDVKTTCLAAHALPPEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCPPIDLFRQYKVPMALASDANP
GTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGVQQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVF
RGEVRP

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=351, Percent_Identity=36.1823361823362, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17555004, Length=339, Percent_Identity=35.1032448377581, Blast_Score=197, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 43822; Mature: 43822

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYE
CCEEEECCCCEECCEEEEEECCCEEEEECCEEEEECCEEEEECCCCCCCCHHHHHHHHHC
GGLITPGLIDCHTHLVFGDDRSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLL
CCCCCCCCEECEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
EQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARRLGELLPIDVKTTCLAAHALP
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
PEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEE
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCP
EEHHHHHHHHCCHHHHHHEECCHHHHHHCCHHHHHHHHCCCEEEEEECCCEEEEECCCCC
PIDLFRQYKVPMALASDANPGTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGV
CHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHCCC
QQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVFRGEVRP
HHCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEECCCCC
>Mature Secondary Structure
MVSVTHCDSLWFGADIITMRGGNYQLIPQGAIAVTGDKIVWIGPHAELPPIHAARQVVYE
CCEEEECCCCEECCEEEEEECCCEEEEECCEEEEECCEEEEECCCCCCCCHHHHHHHHHC
GGLITPGLIDCHTHLVFGDDRSNEFEQRLNGVSYAEIAANGGGIISTVRATRQASEQQLL
CCCCCCCCEECEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
EQALFRLKPLLAEGVTTIEIKSGYGLNLESEIKMLRVARRLGELLPIDVKTTCLAAHALP
HHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
PEFIGQPDDYIDVVCNSIIPQVAVENLADAVDAFCEHLAFSPAQVERVFLAAQKAGLPVK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEE
LHAEQLSALRGATLAAKFHAISADHLEYATESDVQAMANAGTVAVLLPGAYYLLRETQCP
EEHHHHHHHHCCHHHHHHEECCHHHHHHCCHHHHHHHHCCCEEEEEECCCEEEEECCCCC
PIDLFRQYKVPMALASDANPGTSPVLSLRLMLNMACTLFRMTPEEALAGVTCHAAQALGV
CHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHCCC
QQTQGTLETGKLANWVHWPLSHPAELAYWLGGQLPATVVFRGEVRP
HHCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA