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The map label for this gene is appA [H]

Identifier: 218928783

GI number: 218928783

Start: 1873753

End: 1875078

Strand: Direct

Name: appA [H]

Synonym: YPO1648

Alternate gene names: 218928783

Gene position: 1873753-1875078 (Clockwise)

Preceding gene: 218928782

Following gene: 218928790

Centisome position: 40.26

GC content: 48.79

Gene sequence:

>1326_bases
ATGTCAGTATTAGAAAATCGTGTACGGCTATCTGGGCTGGTATTGATGCTAAGCGGATTGGCTGCTATTACTGCGCCGGT
AGCCGCCGAGCCATCGGGCTATACTTTAGAACGTGTGGTTATTTTGAGTCGCCATGGTGTTCGCTCGCCGACCAAACAAA
CGCAGCTTATGAATGATGTTACGCCAGATAAGTGGCCACAATGGCCGGTAAAAGCGGGGTATTTAACGCCACGTGGTGCG
GAGTTGGTCACATTGATGGGGGGGTTTTATGGTGATTACTTTCGCAGCCTTGGTTTGTTAGCGGCGGGATGTCCGGCAGA
GGGGGGGGTATATGCACAGGCAGATATCGATCAACGTACCCGCTTAACCGGACAGGCATTTCTTGATGGTGTGGCTCCGG
GGTGTGGTTTGACCGTGCATAATCAGGCCGATTTGAAAAAGACCGATCCCCTGTTCCATCCGGTAGAGGCTGGCGTGTGT
AAGTTAGACGCCGCACAAACAGATAAAGCGATTGAAGAACAGTTGGGCGGGCCGTTAGATACGGTGAGCCAGCGCTACGC
TAAACCTTTTGCCCAGATGGGGGACGTGCTGAATTTTGCGGCTTCTCCTTATTGCAAATCTTTGCAACAGCAAGGAAAAA
CGTGTGATTTTGCCCACTTTGCGGCCAATGAAGTTAACGTTAATAAAGAAGGGACAAAAGTGACCCTCAGTGGGCCACTG
GCGTTATCATCGACATTGGGTGAAATCTTCTTATTACAAAACGCACAAGCCATGCCAGAGGTTGCCTGGCAACGGCTAAA
AGGGGCGGAGAATTGGGTATCCTTATTGTCATTACATAACGCGCAATTTAATTTAATGGCAAAAACACCGTATATCGCCC
GTCATAAAGGGACGCCATTATTACAGCAGATAGATACGGCTTTAACCCTTCAACTGGATGCTCAGGGGCAAAAGCTACCC
ATTTCAGCCCAAAACCGGGTCTTGTTCCTCGGTGGGCATGATACCAATATTGCCAATATTGCGGGTATGCTGGGAGCCGA
CTGGCAGCTACCCGAGCAACCTGATAATACTCCACCAGGTGGGGGATTGGTTTTTGAACTATGGCAAAATCCGGATAACC
ACCAGCGCTACGTTGCGGTGAAGATGTTCTACCAAACGATGGATCAGTTGCGTAATGCCGAAAAATTGGATCTGAAAAAT
AACCCAGCGGGTATTATTTCCGTTGCAGTTGCTGGTTGTGAAAATAACGGTGACGATAAGCTTTGCGAGCTTGATACATT
CCAAAAGAAAGTGGCTAAGGTAATTGAACCTGCCTGCCACATCTAA

Upstream 100 bases:

>100_bases
TTATATCAATCTTATTGTGCTTCTACATTGTTAGCCAGACGATCGTAAACCATACTCGATGAAGTCAAAATATTCGCAGT
TTTAATAAGGATATAGAATC

Downstream 100 bases:

>100_bases
ATGGATATTATCTGGTTGGCATTAACACCAACCGGATTACATATGATGGCATCTTATTATTACGGCGGGTCGTATTCAGG
TAATTACAGTTGATATTATT

Product: phosphoanhydride phosphorylase

Products: NA

Alternate protein names: Phosphoanhydride phosphohydrolase; pH 2.5 acid phosphatase; AP; 4-phytase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSVLENRVRLSGLVLMLSGLAAITAPVAAEPSGYTLERVVILSRHGVRSPTKQTQLMNDVTPDKWPQWPVKAGYLTPRGA
ELVTLMGGFYGDYFRSLGLLAAGCPAEGGVYAQADIDQRTRLTGQAFLDGVAPGCGLTVHNQADLKKTDPLFHPVEAGVC
KLDAAQTDKAIEEQLGGPLDTVSQRYAKPFAQMGDVLNFAASPYCKSLQQQGKTCDFAHFAANEVNVNKEGTKVTLSGPL
ALSSTLGEIFLLQNAQAMPEVAWQRLKGAENWVSLLSLHNAQFNLMAKTPYIARHKGTPLLQQIDTALTLQLDAQGQKLP
ISAQNRVLFLGGHDTNIANIAGMLGADWQLPEQPDNTPPGGGLVFELWQNPDNHQRYVAVKMFYQTMDQLRNAEKLDLKN
NPAGIISVAVAGCENNGDDKLCELDTFQKKVAKVIEPACHI

Sequences:

>Translated_441_residues
MSVLENRVRLSGLVLMLSGLAAITAPVAAEPSGYTLERVVILSRHGVRSPTKQTQLMNDVTPDKWPQWPVKAGYLTPRGA
ELVTLMGGFYGDYFRSLGLLAAGCPAEGGVYAQADIDQRTRLTGQAFLDGVAPGCGLTVHNQADLKKTDPLFHPVEAGVC
KLDAAQTDKAIEEQLGGPLDTVSQRYAKPFAQMGDVLNFAASPYCKSLQQQGKTCDFAHFAANEVNVNKEGTKVTLSGPL
ALSSTLGEIFLLQNAQAMPEVAWQRLKGAENWVSLLSLHNAQFNLMAKTPYIARHKGTPLLQQIDTALTLQLDAQGQKLP
ISAQNRVLFLGGHDTNIANIAGMLGADWQLPEQPDNTPPGGGLVFELWQNPDNHQRYVAVKMFYQTMDQLRNAEKLDLKN
NPAGIISVAVAGCENNGDDKLCELDTFQKKVAKVIEPACHI
>Mature_440_residues
SVLENRVRLSGLVLMLSGLAAITAPVAAEPSGYTLERVVILSRHGVRSPTKQTQLMNDVTPDKWPQWPVKAGYLTPRGAE
LVTLMGGFYGDYFRSLGLLAAGCPAEGGVYAQADIDQRTRLTGQAFLDGVAPGCGLTVHNQADLKKTDPLFHPVEAGVCK
LDAAQTDKAIEEQLGGPLDTVSQRYAKPFAQMGDVLNFAASPYCKSLQQQGKTCDFAHFAANEVNVNKEGTKVTLSGPLA
LSSTLGEIFLLQNAQAMPEVAWQRLKGAENWVSLLSLHNAQFNLMAKTPYIARHKGTPLLQQIDTALTLQLDAQGQKLPI
SAQNRVLFLGGHDTNIANIAGMLGADWQLPEQPDNTPPGGGLVFELWQNPDNHQRYVAVKMFYQTMDQLRNAEKLDLKNN
PAGIISVAVAGCENNGDDKLCELDTFQKKVAKVIEPACHI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histidine acid phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1787215, Length=436, Percent_Identity=45.8715596330275, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1787237, Length=432, Percent_Identity=30.787037037037, Blast_Score=204, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000560 [H]

Pfam domain/function: PF00328 Acid_phosphat_A [H]

EC number: =3.1.3.2; =3.1.3.26 [H]

Molecular weight: Translated: 47785; Mature: 47654

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00616 HIS_ACID_PHOSPHAT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLENRVRLSGLVLMLSGLAAITAPVAAEPSGYTLERVVILSRHGVRSPTKQTQLMNDV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCC
TPDKWPQWPVKAGYLTPRGAELVTLMGGFYGDYFRSLGLLAAGCPAEGGVYAQADIDQRT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCHHH
RLTGQAFLDGVAPGCGLTVHNQADLKKTDPLFHPVEAGVCKLDAAQTDKAIEEQLGGPLD
HHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHCCCEECCHHHHHHHHHHHHCCCHH
TVSQRYAKPFAQMGDVLNFAASPYCKSLQQQGKTCDFAHFAANEVNVNKEGTKVTLSGPL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCEECCCCCCEEEEECCH
ALSSTLGEIFLLQNAQAMPEVAWQRLKGAENWVSLLSLHNAQFNLMAKTPYIARHKGTPL
HHHHHHHHEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCEEECCCCCHH
LQQIDTALTLQLDAQGQKLPISAQNRVLFLGGHDTNIANIAGMLGADWQLPEQPDNTPPG
HHHHCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GGLVFELWQNPDNHQRYVAVKMFYQTMDQLRNAEKLDLKNNPAGIISVAVAGCENNGDDK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
LCELDTFQKKVAKVIEPACHI
EEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLENRVRLSGLVLMLSGLAAITAPVAAEPSGYTLERVVILSRHGVRSPTKQTQLMNDV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHCC
TPDKWPQWPVKAGYLTPRGAELVTLMGGFYGDYFRSLGLLAAGCPAEGGVYAQADIDQRT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEECCCHHH
RLTGQAFLDGVAPGCGLTVHNQADLKKTDPLFHPVEAGVCKLDAAQTDKAIEEQLGGPLD
HHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHCCCEECCHHHHHHHHHHHHCCCHH
TVSQRYAKPFAQMGDVLNFAASPYCKSLQQQGKTCDFAHFAANEVNVNKEGTKVTLSGPL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCCEECCCCCCEEEEECCH
ALSSTLGEIFLLQNAQAMPEVAWQRLKGAENWVSLLSLHNAQFNLMAKTPYIARHKGTPL
HHHHHHHHEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCEEECCCCCHH
LQQIDTALTLQLDAQGQKLPISAQNRVLFLGGHDTNIANIAGMLGADWQLPEQPDNTPPG
HHHHCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GGLVFELWQNPDNHQRYVAVKMFYQTMDQLRNAEKLDLKNNPAGIISVAVAGCENNGDDK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
LCELDTFQKKVAKVIEPACHI
EEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168385; 8905232; 9278503; 3038201; 1658595; 8387749; 10696472; 1429631; 10655611 [H]