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The map label for this gene is yadA [H]

Identifier: 218928536

GI number: 218928536

Start: 1566262

End: 1568130

Strand: Direct

Name: yadA [H]

Synonym: YPO1388

Alternate gene names: 218928536

Gene position: 1566262-1568130 (Clockwise)

Preceding gene: 218928535

Following gene: 218928537

Centisome position: 33.66

GC content: 38.74

Gene sequence:

>1869_bases
ATGAATAAGGAAATTAAACGGATGCAACGGATGCAATGCATATATATCGCCACTTGGTTAATCGCAGTATTTACTTCGCC
GATAGTGATAGCTAACAATACGAATATTAATGGCAGTACCAATAATAACGGTAATGGTACAATCAATATTTTTGACGCCA
GCAGTAATAACGATATTCATACACTAACCGGTCTTGGTAATGAGCAGTTGGGAGGATTTAGTAATCATCTTATCGACTCT
CATAATAATACGATAGACGGTGGTCAGAGTAACAACCTGGTAAGTAGCGATGGCAATATGATCAGCGCCATTAGCTTGGG
CGATGGCCTCTTCTACGGCGCGCAGAATAACACGTTAATAAACTCAAACAACAACCTACTTATTGTCACTCAGGGCAGTA
CTATAATAGATTCTGATAGTAATACTGTGTCTGGCATTAGTAATAATCTTATAGAGAGCAACAGCAATATTATCGGTAAT
GAAAATAGTTGTTATTCGGATCCCGCGTCCCCATCAGGAGCGTGGTGCGTTGACAATCAAAATACGCTCATTGGCAGTGA
TAACAATACGATCACTGGTGCGCTGAATGGTCTTCACAACAGTCATAACAATGATATTATTGCTAGCTCTGTAAATAATT
TAATGGATACGCATAATAATATTATCGCGGGAGGGCACTACAACACCATTAGTGGTGGTGGAAACAATGACATTTTTGGG
AGTGAAAACAATGTTACTGACAGCACCGACGCCAATATCAATGGTAGTAATAACTACGTGATAGATGGGAATGGAATTGG
TCGAGATGATTTGACTGAAGATAACTCTATATTGGGCGGCTCTGGCAATATGGGCGTGGGGGATTCAGTAACCGCGATTA
CCAATAGCGTGGTGTTCGGCGGTAATACATCTGGTAATTCAACCGGCTCCACTCTGACAGATTCTGTATCGGTTAGCGGC
AACGGTACATCGGGGAATAATGTCGTTAATATCGGCGGAGCGGCAAACGGTAATAATAGTGCTAGCTTAGGTACAGGCTC
GGTATCCTCTGAAGGAGGAATTGCATTGGGTAGCGGTTCGATTGCTACACGGAATGATGAACTGAATATCGGTGATAGAC
AAATTACCAGCGTTAAAAAAGGTGTTGAGAATACAGATACAATCAATGTTAGTCAGTTAAACGATAGCTTTGATGATGTT
CTGAATTTATCAAATGAATATTCTGACAACTCTTTTTCCACTGTCACTGAAAATATAAATAATTATACTGATGCCTCATT
AGATACTGTGTTGAATACAACTGGTGAATATACCGACAACTCAATATTATTGGTTACTAATGAAAGCAATAATTATACTG
ACAATGGCATGGAGAGTGTTAGTAATTATGCAAATATCTATGCTGATGAATCTTTGTTAGCTATCTATAATGAAGAGGCT
AATTACATGTCTAATCTTATAGATGTGACGTTAAATAATGCTAATAACTATACTGATCTTTCAGTTAATACCATTATATA
TACCGGAAAACAATATACAGACTCTCGAATCAATGAGTACCAACGTACTTTTAAAAATGAATTTTTAACCTATTCTAATG
GAAAATTTGGCGGTTTTGATAAAGATATTAATCAAAAGCAGAAACAATTAAACGCGGGAATAGCGGCGACGATGGCTGCT
GCGGTTATTCCTCAAAAATCGGGTTCTAAAGTCTCTATTGGTGTCGGGCTTGCAGGATATAGCGATCAAGGCGCAGGATC
TGTGGGAGCGATTTGGCATGTAAATCAACGAATCACAATGAATACAACGATGACTTACGATACTCAACGTGGTGTTAGTT
TATTAACGGGTTTATCTATCGGCATATGA

Upstream 100 bases:

>100_bases
ACTGGAACATCAATCATAAAACGATAACGCGAGTCAATGTTTCTGCCGACACTGAAGGCGGTGTCGGTGTTGCAGCGGGT
TTTGCTTTTGGCATTAATTA

Downstream 100 bases:

>100_bases
TCGATACCCGTCGTCCTTCAAGATGTAGGGGGAAGCGGCCCTTATTACTCGGCCCGTCCTTGGGCCTCGCCTCTGCGAGG
CCGCTGCAAGCAGCGTTCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MNKEIKRMQRMQCIYIATWLIAVFTSPIVIANNTNINGSTNNNGNGTINIFDASSNNDIHTLTGLGNEQLGGFSNHLIDS
HNNTIDGGQSNNLVSSDGNMISAISLGDGLFYGAQNNTLINSNNNLLIVTQGSTIIDSDSNTVSGISNNLIESNSNIIGN
ENSCYSDPASPSGAWCVDNQNTLIGSDNNTITGALNGLHNSHNNDIIASSVNNLMDTHNNIIAGGHYNTISGGGNNDIFG
SENNVTDSTDANINGSNNYVIDGNGIGRDDLTEDNSILGGSGNMGVGDSVTAITNSVVFGGNTSGNSTGSTLTDSVSVSG
NGTSGNNVVNIGGAANGNNSASLGTGSVSSEGGIALGSGSIATRNDELNIGDRQITSVKKGVENTDTINVSQLNDSFDDV
LNLSNEYSDNSFSTVTENINNYTDASLDTVLNTTGEYTDNSILLVTNESNNYTDNGMESVSNYANIYADESLLAIYNEEA
NYMSNLIDVTLNNANNYTDLSVNTIIYTGKQYTDSRINEYQRTFKNEFLTYSNGKFGGFDKDINQKQKQLNAGIAATMAA
AVIPQKSGSKVSIGVGLAGYSDQGAGSVGAIWHVNQRITMNTTMTYDTQRGVSLLTGLSIGI

Sequences:

>Translated_622_residues
MNKEIKRMQRMQCIYIATWLIAVFTSPIVIANNTNINGSTNNNGNGTINIFDASSNNDIHTLTGLGNEQLGGFSNHLIDS
HNNTIDGGQSNNLVSSDGNMISAISLGDGLFYGAQNNTLINSNNNLLIVTQGSTIIDSDSNTVSGISNNLIESNSNIIGN
ENSCYSDPASPSGAWCVDNQNTLIGSDNNTITGALNGLHNSHNNDIIASSVNNLMDTHNNIIAGGHYNTISGGGNNDIFG
SENNVTDSTDANINGSNNYVIDGNGIGRDDLTEDNSILGGSGNMGVGDSVTAITNSVVFGGNTSGNSTGSTLTDSVSVSG
NGTSGNNVVNIGGAANGNNSASLGTGSVSSEGGIALGSGSIATRNDELNIGDRQITSVKKGVENTDTINVSQLNDSFDDV
LNLSNEYSDNSFSTVTENINNYTDASLDTVLNTTGEYTDNSILLVTNESNNYTDNGMESVSNYANIYADESLLAIYNEEA
NYMSNLIDVTLNNANNYTDLSVNTIIYTGKQYTDSRINEYQRTFKNEFLTYSNGKFGGFDKDINQKQKQLNAGIAATMAA
AVIPQKSGSKVSIGVGLAGYSDQGAGSVGAIWHVNQRITMNTTMTYDTQRGVSLLTGLSIGI
>Mature_622_residues
MNKEIKRMQRMQCIYIATWLIAVFTSPIVIANNTNINGSTNNNGNGTINIFDASSNNDIHTLTGLGNEQLGGFSNHLIDS
HNNTIDGGQSNNLVSSDGNMISAISLGDGLFYGAQNNTLINSNNNLLIVTQGSTIIDSDSNTVSGISNNLIESNSNIIGN
ENSCYSDPASPSGAWCVDNQNTLIGSDNNTITGALNGLHNSHNNDIIASSVNNLMDTHNNIIAGGHYNTISGGGNNDIFG
SENNVTDSTDANINGSNNYVIDGNGIGRDDLTEDNSILGGSGNMGVGDSVTAITNSVVFGGNTSGNSTGSTLTDSVSVSG
NGTSGNNVVNIGGAANGNNSASLGTGSVSSEGGIALGSGSIATRNDELNIGDRQITSVKKGVENTDTINVSQLNDSFDDV
LNLSNEYSDNSFSTVTENINNYTDASLDTVLNTTGEYTDNSILLVTNESNNYTDNGMESVSNYANIYADESLLAIYNEEA
NYMSNLIDVTLNNANNYTDLSVNTIIYTGKQYTDSRINEYQRTFKNEFLTYSNGKFGGFDKDINQKQKQLNAGIAATMAA
AVIPQKSGSKVSIGVGLAGYSDQGAGSVGAIWHVNQRITMNTTMTYDTQRGVSLLTGLSIGI

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 65281; Mature: 65281

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEIKRMQRMQCIYIATWLIAVFTSPIVIANNTNINGSTNNNGNGTINIFDASSNNDIH
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEE
TLTGLGNEQLGGFSNHLIDSHNNTIDGGQSNNLVSSDGNMISAISLGDGLFYGAQNNTLI
EEECCCCHHCCCCHHHEECCCCCCCCCCCCCCEEECCCCEEEEEEECCCEEECCCCCEEE
NSNNNLLIVTQGSTIIDSDSNTVSGISNNLIESNSNIIGNENSCYSDPASPSGAWCVDNQ
ECCCCEEEEECCCEEEECCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEECCC
NTLIGSDNNTITGALNGLHNSHNNDIIASSVNNLMDTHNNIIAGGHYNTISGGGNNDIFG
CEEEECCCCEEEEEECCCCCCCCCCEEHHHHHHHHHCCCCEEECCCEEECCCCCCCCCCC
SENNVTDSTDANINGSNNYVIDGNGIGRDDLTEDNSILGGSGNMGVGDSVTAITNSVVFG
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEECCCCCCCCCCCHHHEECEEEEC
GNTSGNSTGSTLTDSVSVSGNGTSGNNVVNIGGAANGNNSASLGTGSVSSEGGIALGSGS
CCCCCCCCCCEEECEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCC
IATRNDELNIGDRQITSVKKGVENTDTINVSQLNDSFDDVLNLSNEYSDNSFSTVTENIN
EEECCCCCCCCCHHHHHHHHCCCCCCEEEHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHC
NYTDASLDTVLNTTGEYTDNSILLVTNESNNYTDNGMESVSNYANIYADESLLAIYNEEA
CCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEECCCH
NYMSNLIDVTLNNANNYTDLSVNTIIYTGKQYTDSRINEYQRTFKNEFLTYSNGKFGGFD
HHHHCEEEEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCCCCC
KDINQKQKQLNAGIAATMAAAVIPQKSGSKVSIGVGLAGYSDQGAGSVGAIWHVNQRITM
CHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCEEEE
NTTMTYDTQRGVSLLTGLSIGI
EEEEEECCCCCHHHHHHHCCCC
>Mature Secondary Structure
MNKEIKRMQRMQCIYIATWLIAVFTSPIVIANNTNINGSTNNNGNGTINIFDASSNNDIH
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEE
TLTGLGNEQLGGFSNHLIDSHNNTIDGGQSNNLVSSDGNMISAISLGDGLFYGAQNNTLI
EEECCCCHHCCCCHHHEECCCCCCCCCCCCCCEEECCCCEEEEEEECCCEEECCCCCEEE
NSNNNLLIVTQGSTIIDSDSNTVSGISNNLIESNSNIIGNENSCYSDPASPSGAWCVDNQ
ECCCCEEEEECCCEEEECCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCCEEECCC
NTLIGSDNNTITGALNGLHNSHNNDIIASSVNNLMDTHNNIIAGGHYNTISGGGNNDIFG
CEEEECCCCEEEEEECCCCCCCCCCEEHHHHHHHHHCCCCEEECCCEEECCCCCCCCCCC
SENNVTDSTDANINGSNNYVIDGNGIGRDDLTEDNSILGGSGNMGVGDSVTAITNSVVFG
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEECCCCCCCCCCCHHHEECEEEEC
GNTSGNSTGSTLTDSVSVSGNGTSGNNVVNIGGAANGNNSASLGTGSVSSEGGIALGSGS
CCCCCCCCCCEEECEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCC
IATRNDELNIGDRQITSVKKGVENTDTINVSQLNDSFDDVLNLSNEYSDNSFSTVTENIN
EEECCCCCCCCCHHHHHHHHCCCCCCEEEHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHC
NYTDASLDTVLNTTGEYTDNSILLVTNESNNYTDNGMESVSNYANIYADESLLAIYNEEA
CCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHEEECCCEEEEECCCH
NYMSNLIDVTLNNANNYTDLSVNTIIYTGKQYTDSRINEYQRTFKNEFLTYSNGKFGGFD
HHHHCEEEEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCCCCC
KDINQKQKQLNAGIAATMAAAVIPQKSGSKVSIGVGLAGYSDQGAGSVGAIWHVNQRITM
CHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCEEEE
NTTMTYDTQRGVSLLTGLSIGI
EEEEEECCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2761389; 7934875; 2592347; 1548243 [H]