Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 218928522

GI number: 218928522

Start: 1544025

End: 1544987

Strand: Reverse

Name: trxB [H]

Synonym: YPO1374

Alternate gene names: 218928522

Gene position: 1544987-1544025 (Counterclockwise)

Preceding gene: 218928529

Following gene: 218928521

Centisome position: 33.2

GC content: 51.51

Gene sequence:

>963_bases
ATGAGCACGGCTAAACATAGCAAATTGATTATTTTGGGTTCTGGCCCTGCGGGTTACACCGCGGCAGTTTATGCCGCACG
TGCCAACCTGAAACCGGTATTGATTACCGGGATGGAAAAGGGCGGGCAGTTGACCACCACCACAGAGGTAGAGAACTGGC
CAGGTGACCCGGAAGGTTTGACCGGGCCAGCACTGATGGAACGTATGCACGAGCATGCTGAAAAATTCCAAACAGAGATT
ATTTTCGACCATATCAGCAGCGTTGATCTGCAAAACCGTCCATTCCGCCTGTTTGGCGACGGTGCAGAATACACTTGTGA
TGCCCTGATTATCGCGACCGGTGCTTCTGCCCGTTATTTAGGGATGGCGTCAGAAGAAGCCTTTAAAGGAAAAGGGGTTT
CTGCCTGTGCAACCTGTGATGGATTCTTCTATCGTAACCAGAAAGTTGCCGTTGTCGGTGGTGGGAATACGGCGGTTGAA
GAGGCGCTGTATCTGGCGAATATTGCCGCTGAAGTCCATTTAATTCATCGCCGTGACACGTTCCGCTCAGAAAAGATCCT
GATCGACCGCCTGATGGAAAAAGTGAAGAACGGCAATATCGTGCTGCACACAGACCGTACTCTGGATGAGGTTCTGGGTG
ATGACATGGGGGTAACGGGTGTACGCCTGAAATCAACCCACAGTGATGAGACCGAAGAGTTAGCCGTTGCGGGTGTGTTC
ATCGCTATCGGCCATAGCCCTAACACCGGTATATTTAGCGACCAACTGGCGTTGGAAAATGGCTATATCAAAGTGCAGTC
TGGCCTCCAAGGCAATGCAACACAGACCTCAATTCCTGGTGTGTTTGCTGCCGGTGATGTGATGGATCATATCTATCGTC
AGGCTATCACCTCCGCGGGGACTGGCTGTATGGCAGCACTGGATGCAGAGCGCTACCTGGACGGGTTGGCAAACGATAAA
TAA

Upstream 100 bases:

>100_bases
TATCAAAAAAATTGCTAACAACATTTTTGTTTGCTTTTTTTAATGTCATATTTTCCCTACAATCACTCATATTATCCGCC
ATTGTGGGAAAGAGGTATTC

Downstream 100 bases:

>100_bases
CGCGCTATTCCATTGAGTTTTTATTGCGACTGATCGCACCGTTTCACCTCGTTCTATACGGGTGGCTACATGGGCCACCC
GCTTTTTTATCTGTTTTCCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSTAKHSKLIILGSGPAGYTAAVYAARANLKPVLITGMEKGGQLTTTTEVENWPGDPEGLTGPALMERMHEHAEKFQTEI
IFDHISSVDLQNRPFRLFGDGAEYTCDALIIATGASARYLGMASEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLANIAAEVHLIHRRDTFRSEKILIDRLMEKVKNGNIVLHTDRTLDEVLGDDMGVTGVRLKSTHSDETEELAVAGVF
IAIGHSPNTGIFSDQLALENGYIKVQSGLQGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLANDK

Sequences:

>Translated_320_residues
MSTAKHSKLIILGSGPAGYTAAVYAARANLKPVLITGMEKGGQLTTTTEVENWPGDPEGLTGPALMERMHEHAEKFQTEI
IFDHISSVDLQNRPFRLFGDGAEYTCDALIIATGASARYLGMASEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLANIAAEVHLIHRRDTFRSEKILIDRLMEKVKNGNIVLHTDRTLDEVLGDDMGVTGVRLKSTHSDETEELAVAGVF
IAIGHSPNTGIFSDQLALENGYIKVQSGLQGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLANDK
>Mature_319_residues
STAKHSKLIILGSGPAGYTAAVYAARANLKPVLITGMEKGGQLTTTTEVENWPGDPEGLTGPALMERMHEHAEKFQTEII
FDHISSVDLQNRPFRLFGDGAEYTCDALIIATGASARYLGMASEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLANIAAEVHLIHRRDTFRSEKILIDRLMEKVKNGNIVLHTDRTLDEVLGDDMGVTGVRLKSTHSDETEELAVAGVFI
AIGHSPNTGIFSDQLALENGYIKVQSGLQGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLANDK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=85.0467289719626, Blast_Score=569, Evalue=1e-163,
Organism=Escherichia coli, GI87081763, Length=300, Percent_Identity=31.6666666666667, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=48.297213622291, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=48, Blast_Score=287, Evalue=2e-78,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34255; Mature: 34124

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAKHSKLIILGSGPAGYTAAVYAARANLKPVLITGMEKGGQLTTTTEVENWPGDPEGL
CCCCCCCEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMHEHAEKFQTEIIFDHISSVDLQNRPFRLFGDGAEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEEECCCCEEE
GMASEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLANIAAEVHLIHRRDT
ECCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCC
FRSEKILIDRLMEKVKNGNIVLHTDRTLDEVLGDDMGVTGVRLKSTHSDETEELAVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCEEEEECCCCCCHHHHEEEEEE
IAIGHSPNTGIFSDQLALENGYIKVQSGLQGNATQTSIPGVFAAGDVMDHIYRQAITSAG
EEECCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDGLANDK
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STAKHSKLIILGSGPAGYTAAVYAARANLKPVLITGMEKGGQLTTTTEVENWPGDPEGL
CCCCCCEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMHEHAEKFQTEIIFDHISSVDLQNRPFRLFGDGAEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEEECCCCEEE
GMASEEAFKGKGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLANIAAEVHLIHRRDT
ECCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCC
FRSEKILIDRLMEKVKNGNIVLHTDRTLDEVLGDDMGVTGVRLKSTHSDETEELAVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCCCCEEEEECCCCCCHHHHEEEEEE
IAIGHSPNTGIFSDQLALENGYIKVQSGLQGNATQTSIPGVFAAGDVMDHIYRQAITSAG
EEECCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDGLANDK
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]