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The map label for this gene is moaC [H]

Identifier: 218928324

GI number: 218928324

Start: 1307934

End: 1308413

Strand: Direct

Name: moaC [H]

Synonym: YPO1160

Alternate gene names: 218928324

Gene position: 1307934-1308413 (Clockwise)

Preceding gene: 218928323

Following gene: 218928325

Centisome position: 28.11

GC content: 53.33

Gene sequence:

>480_bases
ATGACCCAACTGACACACATAAACACCGCAGGCGAAGCCCACATGGTCGATGTCTCGGCAAAGAATGAAACGGTCCGCGA
AGCACGCGCAGAAGCGTTTGTTGACATGCAGGCCGCAACACTGGCGATGATTATCGATGGCAGCCATCACAAAGGGGATG
TGTTCGCGACGGCTCGGATAGCCGGTATTCAGGCAGCCAAAAAAACGTGGGAATTGATCCCGCTGTGCCATCCGTTGCTG
CTGACTAAAGTGGAAGTAAAACTGGAAGCACAGCCAGAGCATAACCGGGTGCGGATCGAAACCTGCTGCCGCCTGACCGG
TAAAACCGGGGTAGAAATGGAAGCCCTTACTGCGGCTTCAGTCGCAGCCCTGACGATTTACGATATGTGCAAAGCGGTAC
AAAAAGACATGATCATCGGCCCGGTACGCCTACTGACAAAGAGTGGCGGGAAATCGGGTGATTTCAAGGTGGATATATGA

Upstream 100 bases:

>100_bases
TGTGAGCGAATTAGCGCCGATGAGCTTACATCAGTAAGTGATTCGGGCAAGTGAATGCCGCTAACCCCCCTGTAATGTCA
AGAACGAAGGGATTTTATTG

Downstream 100 bases:

>100_bases
TTCAGATTCTATTTTTTGCTCAGGTACGTGAACTGGTTGGGGTGGATAAATTACAGCTAGCGGCCGAGTTTCCAACTGTT
GAAGCGCTACGTCAATCCCT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLL
LTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI

Sequences:

>Translated_159_residues
MTQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLL
LTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI
>Mature_158_residues
TQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARIAGIQAAKKTWELIPLCHPLLL
TKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=87.9746835443038, Blast_Score=292, Evalue=6e-81,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.2818791946309, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=54.8387096774194, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=55.6338028169014, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17225; Mature: 17094

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARI
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEHH
AGIQAAKKTWELIPLCHPLLLTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEHEEEECCCCCCEEHHHHHHH
VAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI
HHHHHHHHHHHHHHHCCEECHHHHEECCCCCCCCEEEEC
>Mature Secondary Structure 
TQLTHINTAGEAHMVDVSAKNETVREARAEAFVDMQAATLAMIIDGSHHKGDVFATARI
CCEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEHH
AGIQAAKKTWELIPLCHPLLLTKVEVKLEAQPEHNRVRIETCCRLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEHEEEECCCCCCEEHHHHHHH
VAALTIYDMCKAVQKDMIIGPVRLLTKSGGKSGDFKVDI
HHHHHHHHHHHHHHHCCEECHHHHEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA