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The map label for this gene is fepA [C]

Identifier: 218927375

GI number: 218927375

Start: 180906

End: 182966

Strand: Direct

Name: fepA [C]

Synonym: YPO0164

Alternate gene names: 218927375

Gene position: 180906-182966 (Clockwise)

Preceding gene: 218927373

Following gene: 218927378

Centisome position: 3.89

GC content: 50.51

Gene sequence:

>2061_bases
ATGATATCTGGGAAAAATAAAGTCTGTAAAAAGAAGTTATTAGCGTGTGCGGTTACTTCGGCTATTTCTGCCTTTGCTTC
AAATGCCATTGCTTCAAATGCCATTGCCGATACTACGAGTCTGGCTGCAATGAATCGCTCAGCCATTAATATATCAAGCA
CGCATAACAGTAATAAAAAACTCAATGACGCTGATGTCATCACGGTAACAGCCCCTCTGTATTCGCCACTGGTGGTTGTC
ACATCGCCTAAAGTGCCCCGCCAGCCAGTACCGGCCAGTGACGGTACTGATTATCTGAGGACCATTCCCGGTTTTTCACT
TGTCCGTAACGGGGGGACCAATGGTGATGTGGTGTTCCGTGGCATGTTCGGCTCACGGCTAAAAATTCTGACCGATGGTG
CTGAGATTTTGGGTACCTGCCCATCGCGAATGGATGCGCCAACCTCGTATATTTCACCAGAAAGTTTTGATCTACTCACG
GTTGTCAAAGGGCCGCAATCGGTGCTGTGGGGGCCGGGGGTTTCTGCCGGGACCATTTTATTTGAACGGGAGCGCCCACA
TTTTGACCAGTCTGGCGTCAAAGGTAATGCCAGTGTGTTAGCCGGTTCTAATGGGCGCTGGGATAAAAATCTTGATGCCA
GTTTGGGTAACGAGCAGGGCTATCTGCGGATGATGGGGAATCAGTCTCGGGCTGCTGATTATAAAGACGGTAACAATGTT
CGCGTGCCCTCTCAATGGGATAAGTGGAATGCGGATATGGCGTTGGGCTGGACACCCGATACCGATACATTACTTGAGCT
GTCGGTAGGAAAAGGGAATGGTGAAGCCCGTTATGGCGGTCGCGGTATGGATGGTTCTCAGTTCCTGCGTGAGAGCCTGG
CGGCCCGTGTTGAGAAAAGTAATATTGGCGAGGTGCTGGATAAAATCGAAGCCAAAATTAACTACACCTACGTAGACCAT
ATTATGGATAACAAGACCTTACGTACCCCACCGATGATGGCGATGTCTAGCAATCTGGACCGGCGGATGCTCGGCGGTCG
GGTCATGGGGACCTGGCTGTGGCAGGACCTAAAGCTGGACGCGGGTACCGATATGCAAACCAATACACACCGCAAGAATA
AACAGGGGAACTGGGATAAAAACGCCCGTTTCATGAATAACGGGGTGTTCGGTGAGTTAACCTGGGCGGCAAGTGAACAA
AATAAACTGATCAGCGGGGCGCGTCTTGACCGTCACCAAGTGACGAATTATACCCGCGCAGGTGAGCCGACGCGCTCTGC
TACCCTCCCCGCTGCCTTTATGCGTGTTGAGCATAATCTGGCTAATGCACCGGTGATGTTGTATGCCGGCTTGGGGCATA
CCGAGCGTTTTCCTGACTATTGGGAACTGTTTTCGCCAAAATTCGGGCCAGCAGGCTCTACTAGCGCCTTTGAGGGTGTA
AAAAGCGAAAAAACCACGCAGATTGATATCGGTGGCCAATACAGCGGTGAACAATTTAGGGGGTGGCTCTCCGCTTATAT
TGGCCGGGTTAATGATTTTATCCTGTTTAAATATGATCCAAAAAATCTACGCATCAGCCAGGCCGATAATATTAACGCAA
CCATTATGGGCGGCGAGATGGGGATGGAATATGCCCTCACCCCGTATTGGAAGGCTGATGCCAGTCTGGCTTATGCCTGG
GGGGAAAATACCCGTGATAACCGGCCATTGCCGCAAATTCCACCACTTGAGGCGCGGTTAGGGCTGACATTTGAAGCAGG
CGACTGGAGCAGTTCCGCCTTATGGCGTTTGGTCAATAGCCAGCACCGGGTGGCGATCAACGAAGGGAATGTCGTCGGTA
AAGATTTTTCCAGCAGTGCGGGGTTCGGCGTACTGTCGGCTAACGTCGCCTATAAGGTGAATAAGCAAGTGAAGTTAAGT
AGCGGCATCGATAATTTGCTGAATAAGGCTTACAGCGAACATCTTAATCTGGCGGGTAATAGCGGTTTTGGTTATTCAGT
TAATACCCCTCTGAATGAGCCTGGCCGCACTCTCTGGGCAAAGCTAAACCTAACATTCTAA

Upstream 100 bases:

>100_bases
GATCCAATTATTCCTGATAGAAAGCGAAAAAATATAAAACCACTTTTCTGGTATGGGTAAATATCCCGCCGGAACAATGT
GTATTGCCTAAGGGGAAGTA

Downstream 100 bases:

>100_bases
GGGGCTGAATGCGCTAGCAGAACGTGGCAGGCGATGGCTTGCCACGTTAATAACAATTAATACCAATAACAATTAACACC
AACACCAACACCAACACCAA

Product: putative membrane receptor protein

Products: NA

Alternate protein names: NB-Dependent Receptor; NB Dependent Receptor; Outer Membrane Copper Receptor; NB-Dependent Receptor Protein; Outer Membrane Copper Receptor OprC; Outer Membrane Protein C; Nb-Dependent Receptor; Outer Membrane Protein OprC; Outer Membrane Receptor Protein; NB-Dependent Receptor Plug Domain-Containing; Outer Membrane Insertion C-Terminal Signal; NB-Dependent Outer Membrane Receptor; Outer Membrane Protein Nosa; Outer Membrane Protein; Outer Membrane Receptor Protein Mostly Fe Transport; NosA Protein; NB-Dependent Copper Receptor Protein; Membrane Receptor Protein; B12 Family nB-Dependent Receptor; NB-Dependent Receptor Domain Protein; Outer Membrane Receptor Proteins; Nb-Dependent Copper Receptor; Outer Membrane Protein OprC Complement; N-B Dependent Receptor

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MISGKNKVCKKKLLACAVTSAISAFASNAIASNAIADTTSLAAMNRSAINISSTHNSNKKLNDADVITVTAPLYSPLVVV
TSPKVPRQPVPASDGTDYLRTIPGFSLVRNGGTNGDVVFRGMFGSRLKILTDGAEILGTCPSRMDAPTSYISPESFDLLT
VVKGPQSVLWGPGVSAGTILFERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNV
RVPSQWDKWNADMALGWTPDTDTLLELSVGKGNGEARYGGRGMDGSQFLRESLAARVEKSNIGEVLDKIEAKINYTYVDH
IMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQ
NKLISGARLDRHQVTNYTRAGEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGV
KSEKTTQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYALTPYWKADASLAYAW
GENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLS
SGIDNLLNKAYSEHLNLAGNSGFGYSVNTPLNEPGRTLWAKLNLTF

Sequences:

>Translated_686_residues
MISGKNKVCKKKLLACAVTSAISAFASNAIASNAIADTTSLAAMNRSAINISSTHNSNKKLNDADVITVTAPLYSPLVVV
TSPKVPRQPVPASDGTDYLRTIPGFSLVRNGGTNGDVVFRGMFGSRLKILTDGAEILGTCPSRMDAPTSYISPESFDLLT
VVKGPQSVLWGPGVSAGTILFERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNV
RVPSQWDKWNADMALGWTPDTDTLLELSVGKGNGEARYGGRGMDGSQFLRESLAARVEKSNIGEVLDKIEAKINYTYVDH
IMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQ
NKLISGARLDRHQVTNYTRAGEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGV
KSEKTTQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYALTPYWKADASLAYAW
GENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLS
SGIDNLLNKAYSEHLNLAGNSGFGYSVNTPLNEPGRTLWAKLNLTF
>Mature_686_residues
MISGKNKVCKKKLLACAVTSAISAFASNAIASNAIADTTSLAAMNRSAINISSTHNSNKKLNDADVITVTAPLYSPLVVV
TSPKVPRQPVPASDGTDYLRTIPGFSLVRNGGTNGDVVFRGMFGSRLKILTDGAEILGTCPSRMDAPTSYISPESFDLLT
VVKGPQSVLWGPGVSAGTILFERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNV
RVPSQWDKWNADMALGWTPDTDTLLELSVGKGNGEARYGGRGMDGSQFLRESLAARVEKSNIGEVLDKIEAKINYTYVDH
IMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLDAGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQ
NKLISGARLDRHQVTNYTRAGEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGV
KSEKTTQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEMGMEYALTPYWKADASLAYAW
GENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNSQHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLS
SGIDNLLNKAYSEHLNLAGNSGFGYSVNTPLNEPGRTLWAKLNLTF

Specific function: This Protein Is Involved In The Initial Step Of Iron Uptake By Binding Ferrienterobactin (Fe-Ent), An Iron Chelatin Siderophore That Allows E.Coli To Extract Iron From The Environment. Fepa Also Acts As A Receptor For Colicins B And D. [C]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Integral Membrane Protein. Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 74895; Mature: 74895

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGKNKVCKKKLLACAVTSAISAFASNAIASNAIADTTSLAAMNRSAINISSTHNSNKK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHCCCEEEEECCCCCCCC
LNDADVITVTAPLYSPLVVVTSPKVPRQPVPASDGTDYLRTIPGFSLVRNGGTNGDVVFR
CCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCHHHEECCCCCCCEEEE
GMFGSRLKILTDGAEILGTCPSRMDAPTSYISPESFDLLTVVKGPQSVLWGPGVSAGTIL
ECCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCEEE
FERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNV
EECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCE
RVPSQWDKWNADMALGWTPDTDTLLELSVGKGNGEARYGGRGMDGSQFLRESLAARVEKS
ECCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NIGEVLDKIEAKINYTYVDHIMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLD
HHHHHHHHHHHHEEEEEEHHHHCCCCCCCCCCHHHHCCCCHHHHCCEEEEEHHHEEEEEC
AGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLISGARLDRHQVTNYTRA
CCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCC
GEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGV
CCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCHHHCCC
KSEKTTQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEM
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCEEEEEECCC
GMEYALTPYWKADASLAYAWGENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNS
CCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHCC
QHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDNLLNKAYSEHLNLAGN
CCEEEEECCCEECCCCCCCCCCEEEECCEEEEECCEEEECCCHHHHHHHHHHHHCCCCCC
SGFGYSVNTPLNEPGRTLWAKLNLTF
CCCCEEECCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MISGKNKVCKKKLLACAVTSAISAFASNAIASNAIADTTSLAAMNRSAINISSTHNSNKK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHCCCEEEEECCCCCCCC
LNDADVITVTAPLYSPLVVVTSPKVPRQPVPASDGTDYLRTIPGFSLVRNGGTNGDVVFR
CCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCHHHEECCCCCCCEEEE
GMFGSRLKILTDGAEILGTCPSRMDAPTSYISPESFDLLTVVKGPQSVLWGPGVSAGTIL
ECCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCEEE
FERERPHFDQSGVKGNASVLAGSNGRWDKNLDASLGNEQGYLRMMGNQSRAADYKDGNNV
EECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCE
RVPSQWDKWNADMALGWTPDTDTLLELSVGKGNGEARYGGRGMDGSQFLRESLAARVEKS
ECCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NIGEVLDKIEAKINYTYVDHIMDNKTLRTPPMMAMSSNLDRRMLGGRVMGTWLWQDLKLD
HHHHHHHHHHHHEEEEEEHHHHCCCCCCCCCCHHHHCCCCHHHHCCEEEEEHHHEEEEEC
AGTDMQTNTHRKNKQGNWDKNARFMNNGVFGELTWAASEQNKLISGARLDRHQVTNYTRA
CCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCC
GEPTRSATLPAAFMRVEHNLANAPVMLYAGLGHTERFPDYWELFSPKFGPAGSTSAFEGV
CCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCCHHHCCC
KSEKTTQIDIGGQYSGEQFRGWLSAYIGRVNDFILFKYDPKNLRISQADNINATIMGGEM
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCEEEEEECCC
GMEYALTPYWKADASLAYAWGENTRDNRPLPQIPPLEARLGLTFEAGDWSSSALWRLVNS
CCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHCC
QHRVAINEGNVVGKDFSSSAGFGVLSANVAYKVNKQVKLSSGIDNLLNKAYSEHLNLAGN
CCEEEEECCCEECCCCCCCCCCEEEECCEEEEECCEEEECCCHHHHHHHHHHHHCCCCCC
SGFGYSVNTPLNEPGRTLWAKLNLTF
CCCCEEECCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA