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The map label for this gene is lytF [H]

Identifier: 218906410

GI number: 218906410

Start: 5020245

End: 5022041

Strand: Direct

Name: lytF [H]

Synonym: BCAH820_5324

Alternate gene names: 218906410

Gene position: 5020245-5022041 (Clockwise)

Preceding gene: 218906409

Following gene: 218906411

Centisome position: 94.67

GC content: 39.07

Gene sequence:

>1797_bases
ATGAAAAAATACCTTGCCGGTCTTGCGGCAGTGTCTGTAGCAGGAGGAGCAGCACCTACACTTGATAGTGTTCAAGCTGC
CCCTGAACAAAATACACAAAAAACTGCTACAACTGTCCAAGCTTCTGCATCAAACAGCTCATCTTATACGGTAAACGCTA
GCGTATTACATGTTCGTGCAGGATCAAGTACTTCTCACGACATCATCTCTCGCGTTTATAACGGTCAATCACTAAACGTG
ATTGGCGAAGAAAATGGTTGGTACAAAATTAACATTAATGGAAAAACAGGCTTTGTTAGTGGTGAATTTGTATCAAAAAA
TGGTACAAGCAATTCAAATGTAAGTACAACAGGTGGAAAAAATAAAGTTACTGCTGATGTATTACGTGTACGTACTGCTC
CTAACACTTCTAGTTCTGTTTCAGGACGTGTATATGAAGGACAAACATTAAACGTAATTGGTCAAGAAAATGGTTGGGTA
AAAATCAATCATAATGGACAAGTTGGCTATGTAAGTGGCGAATTCGTATCTGGTGTTTCTTCTAATGCAGGTTCTTCAAA
CAGCAATACGAATAATAATAACCAAGAATCTGTAAAACCAGCAAGCGGAAACTATACAGTAAATGTATCTTCCCTTCGTG
TTCGTACAGGCCCTAGCACTTCTCACACAACTGTAGGTTCTGTTACAAAAGGACAAGTAGTACAAGTTGTTGGCGAAGTG
CAAGATTGGTTCAAAATCAATTATGCAGGTCAAACGGCTTACGTAAGTAAAGACTACGTAACAAAAGGCGGTTCTAGCGA
TAACGTTACACAAGGAAACAACCAAAATAATAATCAAAACAATAATGTAACTGTTCAAACTGGTGGTACTTACGTTGTTA
ACGCAACATCTCTACGCGTTCGTACAGGTCCTGCTACTTACCATAGCGTAATTGGTGGCGTATTAAATGGTACGACATTA
AACGTAATTGGCTCTGAAGGTAGCTGGTTTAAAGTTAACTATCAAGGAAAAACAGGCTACGTTAGTAGCGAATTCATGAA
ATTCGTTAAAGGTGGCACTACTACTCCTGAGCAACCAAAACAACCTGAACAACCTAATCAAGGTGCAATTGGTGACTACT
ACATTAATGCTTCTGCCTTAAATGTACGTAGTGGTGAAGGTACAAATTATAGAATCATAGGCGCACTTCCACAAGGACAG
AAGGTTCAAGTAATCTCTGAAAACTCTGGATGGAGCAAAATTAACTACAACGGTCAAACTGGTTATATCGGAACACGTTA
CCTTTCTAAAACACCAGTTGGCGGCGCAGTAGATAATAATAAGCCTAACAACAACCAAAATAACAATCAAAACAATAACA
ACAATAACAACAATAACAACAATAACAACAATAACAACAATAACAACAATAACAACAATACAGGTAATAATAGCGGCAAC
AGTTCTTCCATACTTGCATATGCAAAAGGAATGCAAGGCGTACCATACGTTTGGGGCGGAACTTCTGCTAACGGTGTGGA
CTGCAGTGGCTACATCTACCACGTATTTAAGAAATTTGGTCATAACATTAGCCGTCAAAGTGTTGCGGGATATTGGGGTA
GCCTACCACAAACTTCAAATCCACAACCAGGCGACTTAATTTATTTCCAAAACACTTATAAATCGGGTCCTTCTCACATG
GGTATTTACCTTGGGGGCGGATCATTTATCCAAGCTGGAGATAAAGGTGTAGCAATCGCTTCATTAAGCAATTCTTATTG
GAGTAAGCACTTCTTAGGTTATACGAAAGCACCTTAA

Upstream 100 bases:

>100_bases
CCCGCATAAGTCTWGACAGTAATCGACATGCTCTTTAGAATTTTTAACAGTTGGTAAATATTTCTTCACTACATTACAGA
CAGAAAGGAATCGACAAATT

Downstream 100 bases:

>100_bases
GTTATATTTTTAGAGCCTTCTAGATTACTAGATGGCTCTTTTTATTATGTTTCACCTATATCCCTCAAAAAATAATGTAT
CTATTTTCCTATTTCATACA

Product: enterotoxin

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MKKYLAGLAAVSVAGGAAPTLDSVQAAPEQNTQKTATTVQASASNSSSYTVNASVLHVRAGSSTSHDIISRVYNGQSLNV
IGEENGWYKININGKTGFVSGEFVSKNGTSNSNVSTTGGKNKVTADVLRVRTAPNTSSSVSGRVYEGQTLNVIGQENGWV
KINHNGQVGYVSGEFVSGVSSNAGSSNSNTNNNNQESVKPASGNYTVNVSSLRVRTGPSTSHTTVGSVTKGQVVQVVGEV
QDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRVRTGPATYHSVIGGVLNGTTL
NVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPKQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQ
KVQVISENSGWSKINYNGQTGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNNNNNNNNNNNNNNNNNNNTGNNSGN
SSSILAYAKGMQGVPYVWGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGPSHM
GIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP

Sequences:

>Translated_598_residues
MKKYLAGLAAVSVAGGAAPTLDSVQAAPEQNTQKTATTVQASASNSSSYTVNASVLHVRAGSSTSHDIISRVYNGQSLNV
IGEENGWYKININGKTGFVSGEFVSKNGTSNSNVSTTGGKNKVTADVLRVRTAPNTSSSVSGRVYEGQTLNVIGQENGWV
KINHNGQVGYVSGEFVSGVSSNAGSSNSNTNNNNQESVKPASGNYTVNVSSLRVRTGPSTSHTTVGSVTKGQVVQVVGEV
QDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRVRTGPATYHSVIGGVLNGTTL
NVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPKQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQ
KVQVISENSGWSKINYNGQTGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNNNNNNNNNNNNNNNNNNNTGNNSGN
SSSILAYAKGMQGVPYVWGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGPSHM
GIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP
>Mature_598_residues
MKKYLAGLAAVSVAGGAAPTLDSVQAAPEQNTQKTATTVQASASNSSSYTVNASVLHVRAGSSTSHDIISRVYNGQSLNV
IGEENGWYKININGKTGFVSGEFVSKNGTSNSNVSTTGGKNKVTADVLRVRTAPNTSSSVSGRVYEGQTLNVIGQENGWV
KINHNGQVGYVSGEFVSGVSSNAGSSNSNTNNNNQESVKPASGNYTVNVSSLRVRTGPSTSHTTVGSVTKGQVVQVVGEV
QDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRVRTGPATYHSVIGGVLNGTTL
NVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPKQPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQ
KVQVISENSGWSKINYNGQTGYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNNNNNNNNNNNNNNNNNNNTGNNSGN
SSSILAYAKGMQGVPYVWGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSNPQPGDLIYFQNTYKSGPSHM
GIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=118, Percent_Identity=37.2881355932203, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786421, Length=145, Percent_Identity=29.6551724137931, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788501, Length=151, Percent_Identity=28.476821192053, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: 3.5.1.28

Molecular weight: Translated: 63220; Mature: 63220

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYLAGLAAVSVAGGAAPTLDSVQAAPEQNTQKTATTVQASASNSSSYTVNASVLHVRA
CHHHHHHHHHEEECCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEEEC
GSSTSHDIISRVYNGQSLNVIGEENGWYKININGKTGFVSGEFVSKNGTSNSNVSTTGGK
CCCCHHHHHHHHHCCCEEEEEECCCCEEEEEECCCEEEEECEEEECCCCCCCCEECCCCC
NKVTADVLRVRTAPNTSSSVSGRVYEGQTLNVIGQENGWVKINHNGQVGYVSGEFVSGVS
CCEEEEEEEEECCCCCCCCCCCEEECCCEEEEEECCCCEEEEECCCCEEEECCHHHCCCC
SNAGSSNSNTNNNNQESVKPASGNYTVNVSSLRVRTGPSTSHTTVGSVTKGQVVQVVGEV
CCCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHH
QDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRV
CCEEEEEECCCEEEEEHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEEEE
RTGPATYHSVIGGVLNGTTLNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPK
EECCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCC
QPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQKVQVISENSGWSKINYNGQT
CCCCCCCCCCEEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCC
GYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNNNNNNNNNNNNNNNNNNNTGNNSGN
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSSILAYAKGMQGVPYVWGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSN
CCEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
PQPGDLIYFQNTYKSGPSHMGIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP
CCCCEEEEEECCCCCCCCEEEEEECCCCEEECCCCCEEEEECCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKKYLAGLAAVSVAGGAAPTLDSVQAAPEQNTQKTATTVQASASNSSSYTVNASVLHVRA
CHHHHHHHHHEEECCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEEEC
GSSTSHDIISRVYNGQSLNVIGEENGWYKININGKTGFVSGEFVSKNGTSNSNVSTTGGK
CCCCHHHHHHHHHCCCEEEEEECCCCEEEEEECCCEEEEECEEEECCCCCCCCEECCCCC
NKVTADVLRVRTAPNTSSSVSGRVYEGQTLNVIGQENGWVKINHNGQVGYVSGEFVSGVS
CCEEEEEEEEECCCCCCCCCCCEEECCCEEEEEECCCCEEEEECCCCEEEECCHHHCCCC
SNAGSSNSNTNNNNQESVKPASGNYTVNVSSLRVRTGPSTSHTTVGSVTKGQVVQVVGEV
CCCCCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHH
QDWFKINYAGQTAYVSKDYVTKGGSSDNVTQGNNQNNNQNNNVTVQTGGTYVVNATSLRV
CCEEEEEECCCEEEEEHHHEECCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEEEE
RTGPATYHSVIGGVLNGTTLNVIGSEGSWFKVNYQGKTGYVSSEFMKFVKGGTTTPEQPK
EECCHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCC
QPEQPNQGAIGDYYINASALNVRSGEGTNYRIIGALPQGQKVQVISENSGWSKINYNGQT
CCCCCCCCCCEEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCC
GYIGTRYLSKTPVGGAVDNNKPNNNQNNNQNNNNNNNNNNNNNNNNNNNNNNNTGNNSGN
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSSILAYAKGMQGVPYVWGGTSANGVDCSGYIYHVFKKFGHNISRQSVAGYWGSLPQTSN
CCEEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCC
PQPGDLIYFQNTYKSGPSHMGIYLGGGSFIQAGDKGVAIASLSNSYWSKHFLGYTKAP
CCCCEEEEEECCCCCCCCEEEEEECCCCEEECCCCCEEEEECCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]