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The map label for this gene is yybE [H]

Identifier: 218906396

GI number: 218906396

Start: 5004217

End: 5005101

Strand: Direct

Name: yybE [H]

Synonym: BCAH820_5310

Alternate gene names: 218906396

Gene position: 5004217-5005101 (Clockwise)

Preceding gene: 218906394

Following gene: 218906399

Centisome position: 94.37

GC content: 39.32

Gene sequence:

>885_bases
ATGGAACTGCTCCAGTTAAAATACTTTCAGACAGTTGCACGACTAGAACATATGACAAAGGCAGCTGAAGAATTGCATAT
CGCGCAACCTTCACTCAGCAAAACAATCGCTAGACTCGAAAAGGATTTAGGAGTCTCTTTATTTGATCGCCAAGGCCGAC
AGATTACTTTAAATTCTTTCGGAAAAGTATTTTTAAAACGAGTAGAGCGTATTTTTCATGAATTAAGTGAAGGGGAACGA
GAAATTAAAGATTTAGCCGAATTACAACAAAGCTCTATTACACTGGCCGTTTCTATTCCGAGAATATTACCAGAACTACT
TGGCTCTTTTTTAATAGAACATCCTAACGTTCGATTTCAACAATTTCTTGCATCTACTCCTTCTATGAAACGACAACTAG
ATAATATAGAAATTGACTTTTGTATCTCCTCTGTGCCAATTGAAGGTGAGGAGATTGTTTGGGAACCACTTATTACAGAA
GAAATTTTCTTAGTCGTCCCTTCAGGCCACCGTTTATCCGGCCGAGCAAATATCCACCTGCATGAAGTAAAAGACGAACC
GTTTATTAGTATGAACACTGGCTACGGATTTCGGCACTTAACGGATGAATTTTGTAAAGAAGCTGGTTTCACTCCGCATA
TTGCTTTTGAAGTAGATGAACCGACCGTGATTAGCGACCTCATTAAGCAAGGTCTCGGCATCGCTTTTGTTCCAAGTTTA
ACTTTATTAAAAAACTCTACTTTAGCATCAAGCAAGTTGCGTATTATTGAACCCACTTGTCAGCGAACCATCGGATTAAG
TTGGTCGAAGAAACGCTACTTATCGAAAACCGCCCAGCAATTCCGTGAATTCGTGATCGATTACTTCTCCAATATTAGGG
CGTAA

Upstream 100 bases:

>100_bases
AATGGTTTAACAGATTTACTATACACGTCCATTTCCATACTGTATAATACATCTTTAATTATCAATTCATTCCTTTTGGT
CTATAGAAAGGAGATTCGAA

Downstream 100 bases:

>100_bases
AATGATATCAATAAATAAAAGATGCCATCCCGATAGGATGGCACCTTCTATTGTTCACTTTTCTCTAATTCTATTTCAGC
TAAAAGCGGTAGTACGTTAT

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVSLFDRQGRQITLNSFGKVFLKRVERIFHELSEGER
EIKDLAELQQSSITLAVSIPRILPELLGSFLIEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIVWEPLITE
EIFLVVPSGHRLSGRANIHLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLASSKLRIIEPTCQRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIRA

Sequences:

>Translated_294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVSLFDRQGRQITLNSFGKVFLKRVERIFHELSEGER
EIKDLAELQQSSITLAVSIPRILPELLGSFLIEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIVWEPLITE
EIFLVVPSGHRLSGRANIHLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLASSKLRIIEPTCQRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIRA
>Mature_294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVSLFDRQGRQITLNSFGKVFLKRVERIFHELSEGER
EIKDLAELQQSSITLAVSIPRILPELLGSFLIEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIVWEPLITE
EIFLVVPSGHRLSGRANIHLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLASSKLRIIEPTCQRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIRA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=29.020979020979, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=25.5972696245734, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=24.2320819112628, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI2367136, Length=238, Percent_Identity=29.8319327731092, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.5720164609054, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=24.8, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788748, Length=303, Percent_Identity=24.7524752475248, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789204, Length=254, Percent_Identity=25.1968503937008, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=288, Percent_Identity=22.9166666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=26.4, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=307, Percent_Identity=23.4527687296417, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081904, Length=261, Percent_Identity=28.3524904214559, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=305, Percent_Identity=23.2786885245902, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789506, Length=297, Percent_Identity=23.5690235690236, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33554; Mature: 33554

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVSLFDRQGRQITLNSF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCEEEHHHH
GKVFLKRVERIFHELSEGEREIKDLAELQQSSITLAVSIPRILPELLGSFLIEHPNVRFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHH
QFLASTPSMKRQLDNIEIDFCISSVPIEGEEIVWEPLITEEIFLVVPSGHRLSGRANIHL
HHHHCCCHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCEEEEEECCCCEECCCCCEEE
HEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEECCCH
TLLKNSTLASSKLRIIEPTCQRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIRA
HHHHCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVSLFDRQGRQITLNSF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCEEEHHHH
GKVFLKRVERIFHELSEGEREIKDLAELQQSSITLAVSIPRILPELLGSFLIEHPNVRFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHH
QFLASTPSMKRQLDNIEIDFCISSVPIEGEEIVWEPLITEEIFLVVPSGHRLSGRANIHL
HHHHCCCHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCEEEEEECCCCEECCCCCEEE
HEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEECCCH
TLLKNSTLASSKLRIIEPTCQRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIRA
HHHHCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]