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The map label for this gene is tlpC [H]

Identifier: 218906272

GI number: 218906272

Start: 4887221

End: 4888723

Strand: Reverse

Name: tlpC [H]

Synonym: BCAH820_5184

Alternate gene names: 218906272

Gene position: 4888723-4887221 (Counterclockwise)

Preceding gene: 218906273

Following gene: 218906271

Centisome position: 92.19

GC content: 35.2

Gene sequence:

>1503_bases
ATGGAATGGTTAAAGAAAACTTGTTTTTCTAACCTGGAGAAAGAATCACAGAAAAATCATTTATTGCTGTTTATTACGAT
TTGTAGTTTCTTCCTTGGAATCATCGCGATTGGGTATTACGGATATATTTTTACAGAGAGAGCAATCGCGTTTTGGGTTT
GTGGTATTTCTGTCGTTGTATTTGGAACGCTTCTTACTTTTATAGAAAGTATGGAAGCGATGTATAAATATATCATGACA
TTTATGTTGCTTATGATGTCTTTCATTATGGTACAAGCATTTAATGAAAGCCCGGCTGTATTTCAAATGGTTTATTTTAC
ACTAGCGGTTTCACTTATCTATTTAAGTGAGCGTCTCGTTGTAATTCTCGGCGGAGTGGCAGTTGTTCTTACATTTATCC
TTTGTAGTTATTGGCCGGAGCAATTTTTTGCTTATACAGCTGCATCTGAAGCTGCAAACTTCGCAAGCTTGTTAGCGATC
GTAACAATCGCTATGTGGGGCGTCACGAAAATTGGTTCTAACCTACTGGCTCGTTTAAGTGATGAGAAGCAAGAAGTAAT
GAGAAAAGCTCAGGAGCTAGAAGAGACGCAAAGGCTTATTGAAGAAACAGTTGTGAAACTAGATAGTAATTTTAATTGTT
TAAGAGAAAATATGAATACATCGATGGAGTCGATGAGTGACATTAATTTTGCTTTTGAAGAGGTGGCAGTTGGTACACAA
TCACAATCAGAGATGATGTCACGTTCAGTAGAAGTATTGAACGATATGGAAGGAAATATTGAACAAATCATTTCTCAAGT
AAGAAATGCATCGATTCGTGTTGATGAAAGCTTAGAAATTTCAAAGGGTAGTGTACATACTCTACGAAATTTTGAAGCGA
ATATGAAAAGTTTAAATGATGTTGTTTCACAATCAGGAGTTATATTTAGAGATTTAATGATGCAATCGAAGCAAATTAAT
GAAATTGTAGATGTAATAACGAATATTTCAAGTCAGACGAGTTTACTAGCTTTAAATGCAAATATTGAAGCTGCAAGAGC
AGGTGAACATGGAAAAGGATTTGCTATTGTAGCGAATGAAGTATTAAAGCTTGCAGAAGAATCGAATCGTTCTGCGGGAA
GAATTCAAGGGATTTTGAAGGAATTTAGTAATCAAGCAAGTAAGGTAGAAGTGCAGGTAGAGAAATCAGAAAGAGTACAA
GAAGAGTGTAACGAAATGTTAGCAAGTGTTTTAACAAATGTAACGGATTTAGGAAAGTTTATTGATGCAATTAATGATGT
AATGAGAGAGATTGTTGGTCATCAAGAAAATTTTCAAGTTAAAACGACGAATATCGTAAAGGATGTTACACATGCTTCCA
ATGTAATCCAGCAAACTTCTGCGGCGACAGAAGAAGTGTTAGCAAGTGTGGAAGAAGAAAAGCATCGAAATGATACATCG
GTGAAGACATTACATACTGTTAGCGAGCAAGTGAAATTGTTAGAAGATATTTTAGAAAAGTAA

Upstream 100 bases:

>100_bases
TGTGCAAGGAAAAGATTTAAAGTTTGAGAATAGTGATCATAACCCAGTGAGTGCGGTATTTAAGTTGAAGTAATTAAAGG
CAGAAGGTGGGACTGTATAT

Downstream 100 bases:

>100_bases
TATCACTTAAAAAGAGTACAACGCTTGTGCTCTTTTTTCATTTAAAAGAAGACTTGCTCGGATTTTAATTGCTTTTCTGC
TCGTTTTCTGCCAAGCTTAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTERAIAFWVCGISVVVFGTLLTFIESMEAMYKYIMT
FMLLMMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLVVILGGVAVVLTFILCSYWPEQFFAYTAASEAANFASLLAI
VTIAMWGVTKIGSNLLARLSDEKQEVMRKAQELEETQRLIEETVVKLDSNFNCLRENMNTSMESMSDINFAFEEVAVGTQ
SQSEMMSRSVEVLNDMEGNIEQIISQVRNASIRVDESLEISKGSVHTLRNFEANMKSLNDVVSQSGVIFRDLMMQSKQIN
EIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANEVLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQ
EECNEMLASVLTNVTDLGKFIDAINDVMREIVGHQENFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
VKTLHTVSEQVKLLEDILEK

Sequences:

>Translated_500_residues
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTERAIAFWVCGISVVVFGTLLTFIESMEAMYKYIMT
FMLLMMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLVVILGGVAVVLTFILCSYWPEQFFAYTAASEAANFASLLAI
VTIAMWGVTKIGSNLLARLSDEKQEVMRKAQELEETQRLIEETVVKLDSNFNCLRENMNTSMESMSDINFAFEEVAVGTQ
SQSEMMSRSVEVLNDMEGNIEQIISQVRNASIRVDESLEISKGSVHTLRNFEANMKSLNDVVSQSGVIFRDLMMQSKQIN
EIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANEVLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQ
EECNEMLASVLTNVTDLGKFIDAINDVMREIVGHQENFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
VKTLHTVSEQVKLLEDILEK
>Mature_500_residues
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTERAIAFWVCGISVVVFGTLLTFIESMEAMYKYIMT
FMLLMMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLVVILGGVAVVLTFILCSYWPEQFFAYTAASEAANFASLLAI
VTIAMWGVTKIGSNLLARLSDEKQEVMRKAQELEETQRLIEETVVKLDSNFNCLRENMNTSMESMSDINFAFEEVAVGTQ
SQSEMMSRSVEVLNDMEGNIEQIISQVRNASIRVDESLEISKGSVHTLRNFEANMKSLNDVVSQSGVIFRDLMMQSKQIN
EIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANEVLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQ
EECNEMLASVLTNVTDLGKFIDAINDVMREIVGHQENFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
VKTLHTVSEQVKLLEDILEK

Specific function: Mediates Taxis Toward Dipeptides VIa An Interaction With The Periplasmic Dipeptide-Binding Protein. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Transduce A Signal From The Outsid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=266, Percent_Identity=25.187969924812, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787690, Length=336, Percent_Identity=25.5952380952381, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788195, Length=263, Percent_Identity=29.277566539924, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367378, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789453, Length=197, Percent_Identity=28.4263959390863, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 56098; Mature: 56098

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTERAIAFWVCGISVVV
CCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGTLLTFIESMEAMYKYIMTFMLLMMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VILGGVAVVLTFILCSYWPEQFFAYTAASEAANFASLLAIVTIAMWGVTKIGSNLLARLS
HHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEKQEVMRKAQELEETQRLIEETVVKLDSNFNCLRENMNTSMESMSDINFAFEEVAVGTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SQSEMMSRSVEVLNDMEGNIEQIISQVRNASIRVDESLEISKGSVHTLRNFEANMKSLND
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VVSQSGVIFRDLMMQSKQINEIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANE
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHH
VLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQEECNEMLASVLTNVTDLGKF
HHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAINDVMREIVGHQENFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VKTLHTVSEQVKLLEDILEK
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWLKKTCFSNLEKESQKNHLLLFITICSFFLGIIAIGYYGYIFTERAIAFWVCGISVVV
CCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGTLLTFIESMEAMYKYIMTFMLLMMSFIMVQAFNESPAVFQMVYFTLAVSLIYLSERLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VILGGVAVVLTFILCSYWPEQFFAYTAASEAANFASLLAIVTIAMWGVTKIGSNLLARLS
HHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEKQEVMRKAQELEETQRLIEETVVKLDSNFNCLRENMNTSMESMSDINFAFEEVAVGTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SQSEMMSRSVEVLNDMEGNIEQIISQVRNASIRVDESLEISKGSVHTLRNFEANMKSLND
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VVSQSGVIFRDLMMQSKQINEIVDVITNISSQTSLLALNANIEAARAGEHGKGFAIVANE
HHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHH
VLKLAEESNRSAGRIQGILKEFSNQASKVEVQVEKSERVQEECNEMLASVLTNVTDLGKF
HHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDAINDVMREIVGHQENFQVKTTNIVKDVTHASNVIQQTSAATEEVLASVEEEKHRNDTS
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VKTLHTVSEQVKLLEDILEK
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]