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The map label for this gene is lytH [H]

Identifier: 218906165

GI number: 218906165

Start: 4785606

End: 4786589

Strand: Direct

Name: lytH [H]

Synonym: BCAH820_5077

Alternate gene names: 218906165

Gene position: 4785606-4786589 (Clockwise)

Preceding gene: 218906163

Following gene: 218906169

Centisome position: 90.25

GC content: 41.46

Gene sequence:

>984_bases
ATGCTTCGAAAAATTTCTCTTTTGCTTTCGATTTGCTTTCTTCTCCACCAAAACATCGCTTACGGTGAAGATAATCAGCA
AAGCATATACGAAAAGCGCATGGCACTATATAAAGAAACCGAGCAATCTTCAGGCATTCCGTGGTATTACTTAGCTGCAA
TGGATCAATATGAAAGAAATATACGGAGCGTAAGAAAAGATATTCCGAAAAAACCAGATGCCATCATTTCCCTTTATTTC
AAACCAGAAATATGGGCTGGACCTGTTAATGGTAACGACACTCTCCCCCATACAATTGCTCTATTTGGCGGGTTAGGTTT
AGATGGTGACAAAGATGGATTTGCAAATGCAAATAACGACCGTGACCTTCTGCATACAGCAGCAACAATTTTAAAGAAAC
AAGGAACGTCAGAAGAACGTATCAAAATCATGCTCTGGGAATATTATAGACGTGCAAAAACAGTTGATTTAATTACCGAA
TACGCCCAAATTTATAAACATTATGGCCGTATTAATTTAGAAGGAAATGCTTTTCCCCTTCCTATTCGCAGTGACCATAG
CTACCGTAGTACTTTCGGCGCTGGAAGAAGTTTTGGTGGAAGAAGGGTTCATGAAGGAACCGATATATTCGCAGGCTATG
GCGTACCAGTAAGATCCACTTGCTATGGCATTATTGAAACAAAGGGCTGGAATCGCCTTGGCGGATGGCGCATCGGTATT
CGCGACCTTCATAATAATTATCATTATTACGCTCACTTAGGCGGGTTCTCAAAAGAAATACAGCTTGGACAAATTGTCGA
GCCCGGAAAAGTAATCGGATTTGTTGGTAGCACCGGTTACGGTCCTCCCGGCACAGCTGGAAAATTCCCGCCTCACTTAC
ATTTCGGCATGTATAAAGACAACGGTTATACAGAATGGGCTTTCGATCCATACATGCATTTAAGTCTTTGGGAGCGAAAA
GAACGCGCAAATACAAAACGATAA

Upstream 100 bases:

>100_bases
TCAAATGAAGATTCTAAGATTTTTTCCAATCGTTCCCTATAATGAAATACTCCGTATATCCCACACTAAAAAGAGTGATG
TTGTGAAAGGAGTCTATTTC

Downstream 100 bases:

>100_bases
CCGTAGCACATTGCTACGGTTATTTTTCATTTACAACTAACTATCCGTTTTCTTTTTATTAGGTACAACAACACTTCCGC
TTCCATAATAAGTAGGCACT

Product: peptidase, M23/M37 family

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDAIISLYF
KPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITE
YAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLGGWRIGI
RDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHLSLWERK
ERANTKR

Sequences:

>Translated_327_residues
MLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDAIISLYF
KPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITE
YAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLGGWRIGI
RDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHLSLWERK
ERANTKR
>Mature_327_residues
MLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERNIRSVRKDIPKKPDAIISLYF
KPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANNDRDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITE
YAQIYKHYGRINLEGNAFPLPIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLGGWRIGI
RDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKDNGYTEWAFDPYMHLSLWERK
ERANTKR

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 37327; Mature: 37327

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERN
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
IRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANND
HHHHHHHCCCCCCEEEEEEECCCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
RDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLEGNAFPL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCEEEC
PIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLGGWRIGI
CCCCCCCHHHHHCCCCCCCCCEECCCCCEEEECCCCHHHHEEEEEECCCCCCCCCEEEEH
RDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKD
HHHCCCEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEC
NGYTEWAFDPYMHLSLWERKERANTKR
CCEEEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLRKISLLLSICFLLHQNIAYGEDNQQSIYEKRMALYKETEQSSGIPWYYLAAMDQYERN
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
IRSVRKDIPKKPDAIISLYFKPEIWAGPVNGNDTLPHTIALFGGLGLDGDKDGFANANND
HHHHHHHCCCCCCEEEEEEECCCEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
RDLLHTAATILKKQGTSEERIKIMLWEYYRRAKTVDLITEYAQIYKHYGRINLEGNAFPL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCEEEC
PIRSDHSYRSTFGAGRSFGGRRVHEGTDIFAGYGVPVRSTCYGIIETKGWNRLGGWRIGI
CCCCCCCHHHHHCCCCCCCCCEECCCCCEEEECCCCHHHHEEEEEECCCCCCCCCEEEEH
RDLHNNYHYYAHLGGFSKEIQLGQIVEPGKVIGFVGSTGYGPPGTAGKFPPHLHFGMYKD
HHHCCCEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEC
NGYTEWAFDPYMHLSLWERKERANTKR
CCEEEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]